GB9113219D0 - Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same - Google Patents
Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the sameInfo
- Publication number
- GB9113219D0 GB9113219D0 GB919113219A GB9113219A GB9113219D0 GB 9113219 D0 GB9113219 D0 GB 9113219D0 GB 919113219 A GB919113219 A GB 919113219A GB 9113219 A GB9113219 A GB 9113219A GB 9113219 D0 GB9113219 D0 GB 9113219D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- processes
- preparation
- same
- pharmaceutical composition
- peptide compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919113219A GB9113219D0 (en) | 1991-06-19 | 1991-06-19 | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same |
| PCT/JP1992/000780 WO1992022569A1 (en) | 1991-06-19 | 1992-06-18 | Peptides with tachykinin antagonist activity |
| EP92913210A EP0590152A1 (en) | 1991-06-19 | 1992-06-18 | Peptides with tachykinin antagonist activity |
| JP5500803A JPH07503701A (en) | 1991-06-19 | 1992-06-18 | Peptides with tachykinin antagonistic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919113219A GB9113219D0 (en) | 1991-06-19 | 1991-06-19 | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB9113219D0 true GB9113219D0 (en) | 1991-08-07 |
Family
ID=10696937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB919113219A Pending GB9113219D0 (en) | 1991-06-19 | 1991-06-19 | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0590152A1 (en) |
| JP (1) | JPH07503701A (en) |
| GB (1) | GB9113219D0 (en) |
| WO (1) | WO1992022569A1 (en) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5610140A (en) * | 1991-04-01 | 1997-03-11 | Cortech, Inc. | Bradykinin receptor antagonists with neurokinin receptor blocking activity |
| DE4243496A1 (en) * | 1992-09-03 | 1994-03-10 | Boehringer Ingelheim Kg | New di:peptide neurokinin antagonists - useful in treating respiratory disorders, inflammatory eye and skin disorders, polyarthritis, osteoarthritis and pain |
| DE59309867D1 (en) * | 1992-09-03 | 1999-12-16 | Boehringer Ingelheim Pharma | NEW AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS |
| US5635510A (en) * | 1993-05-06 | 1997-06-03 | Merrell Pharmaceuticals Inc. | Substituted pyrrolidin-3-yl-alkyl-piperidines |
| WO1995000536A1 (en) * | 1993-06-22 | 1995-01-05 | Fujisawa Pharmaceutical Co., Ltd. | Peptide compounds |
| FR2719312B1 (en) * | 1994-04-28 | 1996-06-14 | Adir | New pseudopeptides derived from neurokinins, process for their preparation and pharmaceutical compositions containing them. |
| CA2198084C (en) | 1994-08-25 | 2000-03-28 | Timothy P. Burkholder | Novel substituted piperidines useful for the treatment of allergic diseases |
| JPH11501289A (en) * | 1994-12-02 | 1999-02-02 | 藤沢薬品工業株式会社 | Peptide compounds for prevention and / or treatment of NO-mediated diseases |
| FR2728169A1 (en) | 1994-12-19 | 1996-06-21 | Oreal | USE OF A SUBSTANCE P ANTAGONIST FOR THE TREATMENT OF PRURITUS AND EYE OR PALPEBRAL DYSESTHESIA |
| FR2728166A1 (en) | 1994-12-19 | 1996-06-21 | Oreal | TOPICAL COMPOSITION CONTAINING AN ANTAGONIST OF SUBSTANCE P |
| FR2728165A1 (en) | 1994-12-19 | 1996-06-21 | Oreal | USE OF AN ANTAGONIST OF SUBSTANCE P FOR THE TREATMENT OF SKIN REDNESS OF NEUROGENIC ORIGIN |
| AU700693B2 (en) * | 1995-04-13 | 1999-01-14 | Aventis Pharmaceuticals Inc. | Novel substituted piperazine derivatives having tachykinin receptor antagonists activity |
| DE19541283A1 (en) * | 1995-11-06 | 1997-05-07 | Boehringer Ingelheim Kg | Novel amino acid derivatives, processes for their preparation and pharmaceutical compositions containing these compounds |
| US6211199B1 (en) | 1995-11-17 | 2001-04-03 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases |
| FR2741262B1 (en) | 1995-11-20 | 1999-03-05 | Oreal | USE OF A TNF-ALPHA ANTAGONIST FOR THE TREATMENT OF CUTANEOUS REDNESS OF NEUROGENIC ORIGIN |
| US5916878A (en) * | 1995-11-28 | 1999-06-29 | Edward T. Wei | γ-glutamyl and β-aspartyl containing immunomodulator compounds and methods therewith |
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US5932571A (en) * | 1996-02-21 | 1999-08-03 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases |
| US5998439A (en) * | 1996-02-21 | 1999-12-07 | Hoescht Marion Roussel, Inc. | Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
| US5922737A (en) * | 1996-02-21 | 1999-07-13 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases |
| JP3191038B2 (en) | 1996-06-26 | 2001-07-23 | 輝夫 西田 | Ophthalmic pharmaceutical composition |
| IT1304898B1 (en) * | 1998-09-08 | 2001-04-05 | Menarini Ricerche Spa | PRODUCTS WITH BASIC CHARACTERISTICS HAVING ANTAGONIST ACTIVITIES ON THE NK-1 RECEIVER AND THEIR USE IN PHARMACEUTICAL PREPARATIONS |
| EP1158996A4 (en) | 1999-02-18 | 2005-01-12 | Kaken Pharma Co Ltd | Novel amide derivatives as growth hormone secretagogues |
| US7163949B1 (en) | 1999-11-03 | 2007-01-16 | Amr Technology, Inc. | 4-phenyl substituted tetrahydroisoquinolines and use thereof |
| ES2304984T3 (en) | 1999-11-03 | 2008-11-01 | Amr Technology, Inc. | TETRA-HYDROISOQUINOLINAS OF ARILICA AND HETEROARILICA SUBSTITUTION AND ITS USE TO BLOCK THE RECOVERY OF NOREPINEFRINE, DOPAMINE AND SEROTONINE. |
| JP3673711B2 (en) | 1999-12-27 | 2005-07-20 | キヤノン株式会社 | Polyhydroxyalkanoate and its production method using microorganism |
| RU2301808C2 (en) | 2000-07-11 | 2007-06-27 | Эймр Текнолоджи, Инк. | 4-phenyl-substituted tetrahydroisoquinolines, pharmaceutical composition and method for treatment based on thereof |
| GEP20094640B (en) | 2004-07-15 | 2009-03-10 | Bristol Myers Squibb Co | Aryl-and heteroaryl-substituted tetrahydro isoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| ATE550019T1 (en) | 2005-05-17 | 2012-04-15 | Merck Sharp & Dohme | CIS-4-Ä(4-CHLOROPHENYL)SULFONYLÜ-4-(2,5-DIFLUOROPHENYL)CYCLOHEXANEPROPANE ACID FOR THE TREATMENT OF CANCER |
| CA2610205A1 (en) * | 2005-06-20 | 2006-12-28 | Astrazeneca Ab | Process for the production of (alkoxycarbonylamino)alkyl sulfonates |
| BRPI0613403A2 (en) | 2005-07-15 | 2009-02-10 | Amr Technology Inc | aryl and heteroaryl substituted tetrahydrobenzodiazepines and their use to block reuptake of norepinephrine, dopamine and serotonin |
| CA2624030A1 (en) | 2005-09-29 | 2007-04-12 | Tianying Jian | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators |
| JP2009515984A (en) | 2005-11-15 | 2009-04-16 | バーテックス ファーマシューティカルズ インコーポレイテッド | Azaindazole useful as a kinase inhibitor |
| GB0603041D0 (en) | 2006-02-15 | 2006-03-29 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| EP2083831B1 (en) | 2006-09-22 | 2013-12-25 | Merck Sharp & Dohme Corp. | Method of treatment using fatty acid synthesis inhibitors |
| US20110218176A1 (en) | 2006-11-01 | 2011-09-08 | Barbara Brooke Jennings-Spring | Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development |
| JP4611444B2 (en) | 2007-01-10 | 2011-01-12 | イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー | Amide substituted indazoles as poly (ADP-ribose) polymerase (PARP) inhibitors |
| EP2117538A1 (en) | 2007-01-24 | 2009-11-18 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
| EP2145884B1 (en) | 2007-04-02 | 2014-08-06 | Msd K.K. | Indoledione derivative |
| US8389553B2 (en) | 2007-06-27 | 2013-03-05 | Merck Sharp & Dohme Corp. | 4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
| JP2011515343A (en) | 2008-03-03 | 2011-05-19 | タイガー ファーマテック | Tyrosine kinase inhibitor |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| UA105182C2 (en) | 2008-07-03 | 2014-04-25 | Ньюрексон, Інк. | Benzoxazines, benzothiazines, and related compounds having nos inhibitory activity |
| US8691825B2 (en) | 2009-04-01 | 2014-04-08 | Merck Sharp & Dohme Corp. | Inhibitors of AKT activity |
| EP2429295B1 (en) | 2009-05-12 | 2013-12-25 | Albany Molecular Research, Inc. | Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof |
| JP5739415B2 (en) | 2009-05-12 | 2015-06-24 | ブリストル−マイヤーズ スクウィブ カンパニー | (S) -7-([1,2,4] triazolo [1,5-a] pyridin-6-yl) -4- (3,4-dichlorophenyl) -1,2,3,4-tetrahydroisoquinoline Crystal forms and uses thereof |
| KR101830447B1 (en) | 2009-05-12 | 2018-02-20 | 알바니 몰레큘라 리써치, 인크. | 7-([1,2,4]TRIAZOLO[1,5-α]PYRIDIN-6-YL)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF |
| CN102638981B (en) | 2009-10-14 | 2015-07-22 | 默沙东公司 | Substituted piperidines that increase p53 activity and the uses thereof |
| US8999957B2 (en) | 2010-06-24 | 2015-04-07 | Merck Sharp & Dohme Corp. | Heterocyclic compounds as ERK inhibitors |
| CA2805265A1 (en) | 2010-08-02 | 2012-02-09 | Merck Sharp & Dohme Corp. | Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina) |
| EP2606134B1 (en) | 2010-08-17 | 2019-04-10 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS B VIRUS (HBV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
| EP2608669B1 (en) | 2010-08-23 | 2016-06-22 | Merck Sharp & Dohme Corp. | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS |
| WO2012030685A2 (en) | 2010-09-01 | 2012-03-08 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
| US9242981B2 (en) | 2010-09-16 | 2016-01-26 | Merck Sharp & Dohme Corp. | Fused pyrazole derivatives as novel ERK inhibitors |
| EP2632472B1 (en) | 2010-10-29 | 2017-12-13 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of gene expression using short interfering nucleic acids (sina) |
| EP2654748B1 (en) | 2010-12-21 | 2016-07-27 | Merck Sharp & Dohme Corp. | Indazole derivatives useful as erk inhibitors |
| JP2014514321A (en) | 2011-04-21 | 2014-06-19 | メルク・シャープ・アンド・ドーム・コーポレーション | Insulin-like growth factor 1 receptor inhibitor |
| WO2013004766A1 (en) | 2011-07-04 | 2013-01-10 | Ferrari Giulio | Nk-1 receptor antagonists for treating corneal neovascularisation |
| US9023865B2 (en) | 2011-10-27 | 2015-05-05 | Merck Sharp & Dohme Corp. | Compounds that are ERK inhibitors |
| EP3453762B1 (en) | 2012-05-02 | 2021-04-21 | Sirna Therapeutics, Inc. | Short interfering nucleic acid (sina) compositions |
| US9233979B2 (en) | 2012-09-28 | 2016-01-12 | Merck Sharp & Dohme Corp. | Compounds that are ERK inhibitors |
| RU2660349C2 (en) | 2012-11-28 | 2018-07-05 | Мерк Шарп И Доум Корп. | Compositions and methods for treatment of malignant tumour |
| BR112015013611A2 (en) | 2012-12-20 | 2017-11-14 | Merck Sharp & Dohme | compound and pharmaceutical composition |
| WO2014120748A1 (en) | 2013-01-30 | 2014-08-07 | Merck Sharp & Dohme Corp. | 2,6,7,8 substituted purines as hdm2 inhibitors |
| US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| EP3706742B1 (en) | 2017-11-08 | 2023-03-15 | Merck Sharp & Dohme LLC | Prmt5 inhibitors |
| US20210015834A1 (en) | 2018-02-26 | 2021-01-21 | Ospedale San Raffaele S.R.L. | Nk-1 antagonists for use in the treatment of ocular pain |
| WO2020033282A1 (en) | 2018-08-07 | 2020-02-13 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
| WO2020033284A1 (en) | 2018-08-07 | 2020-02-13 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
| EP4117673A1 (en) | 2020-03-11 | 2023-01-18 | Ospedale San Raffaele S.r.l. | Treatment of stem cell deficiency |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3226241A1 (en) * | 1982-07-14 | 1984-01-26 | Basf Ag, 6700 Ludwigshafen | N-ACYL DERIVATIVES OF PEPTIDES, THEIR PRODUCTION AND USE IN THE FIGHT AGAINST DISEASES AND MEANS THEREFOR |
| US5164372A (en) * | 1989-04-28 | 1992-11-17 | Fujisawa Pharmaceutical Company, Ltd. | Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same |
-
1991
- 1991-06-19 GB GB919113219A patent/GB9113219D0/en active Pending
-
1992
- 1992-06-18 EP EP92913210A patent/EP0590152A1/en not_active Withdrawn
- 1992-06-18 JP JP5500803A patent/JPH07503701A/en active Pending
- 1992-06-18 WO PCT/JP1992/000780 patent/WO1992022569A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0590152A1 (en) | 1994-04-06 |
| JPH07503701A (en) | 1995-04-20 |
| WO1992022569A1 (en) | 1992-12-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB9113219D0 (en) | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same | |
| IL106600A (en) | Peptides, pharmaceutical compositions containing the same and processes for the preparation thereof | |
| IL116211A0 (en) | Peptide compounds pharmaceutical compositions containing the same and processes for the preparation thereof | |
| IL115484A (en) | Polypeptide derivatives processes for the preparation thereof and pharmaceutical compositions containing the same | |
| IL112193A0 (en) | Phenylpyrazolopyridine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same | |
| IL103612A0 (en) | Peptides,their preparation and pharmaceutical compositions containing them | |
| IL100899A0 (en) | Beta-amino-alpha-hydroxycarboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
| PH31073A (en) | Pharmaceutical composition and process for the preparation thereof. | |
| AU2837089A (en) | New indolylpiperidine compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | |
| GB9123353D0 (en) | New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same | |
| IL107358A0 (en) | a-Phosphonosulfonate derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | |
| GB8917687D0 (en) | Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same | |
| IL99500A0 (en) | Naphthalene compounds,processes for the preparation thereof and pharmaceutical compositions containing the same | |
| EP0515995A3 (en) | N-(5-thioxo-l-prolyl)-l-cysteine, derivatives thereof, processes for the preparation thereof and pharmaceutical compositions containing them | |
| GB9310075D0 (en) | New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same | |
| GB9025509D0 (en) | New amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same | |
| IL102116A0 (en) | Hetaryloxy-beta-carboline derivatives,processes for the preparation thereof,and pharmaceutical compositions containing the same | |
| IL107808A0 (en) | Diarylalkane derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | |
| IL99389A0 (en) | Amino acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
| GB9014532D0 (en) | Thiazole compound,processes for the preparation thereof and pharmaceutical composition comprising the same | |
| IL106433A0 (en) | Furylthiazole derivatives,processes for the preparation thereof and pharmaceutical composition containing the same | |
| IL101566A0 (en) | Isoxazolylimidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
| LTIP606A (en) | Peptide compounds, method for the preparation and use thereof | |
| ZA922354B (en) | Pharmaceutical composition and process for the preparation thereof | |
| ZA9364B (en) | Pyridysulphonylure compound, processes for the preparation thereof, and pharmaceutical compositions containing it |