GB863765A - Preparation of l-threonine - Google Patents
Preparation of l-threonineInfo
- Publication number
- GB863765A GB863765A GB7496/59A GB749659A GB863765A GB 863765 A GB863765 A GB 863765A GB 7496/59 A GB7496/59 A GB 7496/59A GB 749659 A GB749659 A GB 749659A GB 863765 A GB863765 A GB 863765A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nutrient medium
- coli
- per litre
- threonine
- diaminopimelic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
L-Threonine is prepared by cultivating Escherichia coli A.T.C.C. 13070 or 13071 under submerged aerobic conditions at temperatures between 20 and 40 DEG C. and at a pH of between 6 and 8 in an aqueous nutrient medium comprising sorbitol or mannitol, sources of nitrogen, magnesium, potassium and trace metals together with from 100 to 140 mg. of diaminopimelic acid per litre of nutrient medium when E. coli A.T.C.C. 13071 is used, or with from 100 to 250 m. of diaminopimelic acid and up to 100 mg. of L-methionine per litre of nutrient medium when E. coli A.T.C.C. 13070 is used. Yields are improved by the addition of Llycine, sucrose, cornsteep liquor and/or crude beet molasses to the nutrient medium. The product is purified by ion exchange techniques, small amounts of glycine, serine and glutamic acid being separated as by-products. Specification 610,527 is referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US863765XA | 1958-03-10 | 1958-03-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB863765A true GB863765A (en) | 1961-03-29 |
Family
ID=22198161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7496/59A Expired GB863765A (en) | 1958-03-10 | 1959-03-04 | Preparation of l-threonine |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB863765A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1806386B1 (en) * | 1968-08-17 | 1970-07-23 | Kyowa Hakko Kogyo Kk | Process for the production of L-threonine |
-
1959
- 1959-03-04 GB GB7496/59A patent/GB863765A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1806386B1 (en) * | 1968-08-17 | 1970-07-23 | Kyowa Hakko Kogyo Kk | Process for the production of L-threonine |
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