GB844946A - New 2-(n-substituted)-acylamino-1,3,4-thiadiazole-5-sulfonamides - Google Patents

New 2-(n-substituted)-acylamino-1,3,4-thiadiazole-5-sulfonamides

Info

Publication number
GB844946A
GB844946A GB843657A GB843657A GB844946A GB 844946 A GB844946 A GB 844946A GB 843657 A GB843657 A GB 843657A GB 843657 A GB843657 A GB 843657A GB 844946 A GB844946 A GB 844946A
Authority
GB
United Kingdom
Prior art keywords
thiadiazole
acylamino
substituted
methyl
sulfonamides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB843657A
Inventor
Richard William Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Priority to GB843657A priority Critical patent/GB844946A/en
Publication of GB844946A publication Critical patent/GB844946A/en
Expired legal-status Critical Current

Links

Abstract

The invention comprises 2-acylamino-1:3:4-thiadiazole-5-sulphonamides of the formula: <FORM:0844946/IV(b)/1> wherein R1 is a hydrogen, alkyl or monocyclic aralkyl and R2 is alkyl or monocyclic aralkyl and their preparation by chlorinating the appropriate 2 - (N - substituted) acylamino - 5 - benzylmercapto-1:3:4-thiadiazole, which maybe obtained by the action of a halide R2-Halogen on a 2-acylamino-5-benzylmercapto-thiadiazole, to give a 2-(N-substituted-acylamino-1:3:4-thiadiazole sulphonyl chloride, and reacting the latter with ammonia. Specified products include 2-N-methyl-acetyl-, N-methyl-formyl-, N-methyl, propionyl-, N-propyl-butyryl-, N-benzyl-acetyl and N-methyl-phenacetyl- 1:3:4-thiadiazole-5-sulphonamide and the corresponding intermediate compounds.
GB843657A 1957-03-14 1957-03-14 New 2-(n-substituted)-acylamino-1,3,4-thiadiazole-5-sulfonamides Expired GB844946A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB843657A GB844946A (en) 1957-03-14 1957-03-14 New 2-(n-substituted)-acylamino-1,3,4-thiadiazole-5-sulfonamides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB843657A GB844946A (en) 1957-03-14 1957-03-14 New 2-(n-substituted)-acylamino-1,3,4-thiadiazole-5-sulfonamides

Publications (1)

Publication Number Publication Date
GB844946A true GB844946A (en) 1960-08-17

Family

ID=9852456

Family Applications (1)

Application Number Title Priority Date Filing Date
GB843657A Expired GB844946A (en) 1957-03-14 1957-03-14 New 2-(n-substituted)-acylamino-1,3,4-thiadiazole-5-sulfonamides

Country Status (1)

Country Link
GB (1) GB844946A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0209996A2 (en) * 1985-06-25 1987-01-28 Siska Diagnostics,Inc. Nucleic acid probes comprising N4 -(substituted amino)cytidines
EP0210021A2 (en) * 1985-07-09 1987-01-28 Siska Diagnostics,Inc. Carbonic anhydrase inhibitor-tagged nucleic acid probes
US4833251A (en) * 1985-06-25 1989-05-23 Siska Diagnostics, Inc. Compounds for tagging nucleic acid probes
US9808531B2 (en) 2015-09-22 2017-11-07 Graybug Vision, Inc. Compounds and compositions for the treatment of ocular disorders
US11548861B2 (en) 2017-03-23 2023-01-10 Graybug Vision, Inc. Drugs and compositions for the treatment of ocular disorders

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0209996A2 (en) * 1985-06-25 1987-01-28 Siska Diagnostics,Inc. Nucleic acid probes comprising N4 -(substituted amino)cytidines
EP0209996A3 (en) * 1985-06-25 1987-09-02 Siska Diagnostics,Inc. Nucleic acid probes comprising n4 -(substituted amino)cytidines
US4833251A (en) * 1985-06-25 1989-05-23 Siska Diagnostics, Inc. Compounds for tagging nucleic acid probes
EP0210021A2 (en) * 1985-07-09 1987-01-28 Siska Diagnostics,Inc. Carbonic anhydrase inhibitor-tagged nucleic acid probes
EP0210021A3 (en) * 1985-07-09 1987-09-02 Siska Diagnostics,Inc. Carbonic anhydrase inhibitor-tagged nucleic acid probes
US9956302B2 (en) 2015-09-22 2018-05-01 Graybug Vision, Inc. Compounds and compositions for the treatment of ocular disorders
US9808531B2 (en) 2015-09-22 2017-11-07 Graybug Vision, Inc. Compounds and compositions for the treatment of ocular disorders
US10098965B2 (en) 2015-09-22 2018-10-16 Graybug Vision, Inc. Compounds and compositions for the treatment of ocular disorders
US10111964B2 (en) 2015-09-22 2018-10-30 Graybug Vision, Inc. Compounds and compositions for the treatment of ocular disorders
US10117950B2 (en) 2015-09-22 2018-11-06 Graybug Vision, Inc. Compounds and compositions for the treatment of ocular disorders
US10159747B2 (en) 2015-09-22 2018-12-25 Graybug Visioon, Inc. Compounds and compositions for the treatment of ocular disorders
US10485876B2 (en) 2015-09-22 2019-11-26 Graybug Vision, Inc. Compounds and compositions for the treatment of ocular disorders
US11548861B2 (en) 2017-03-23 2023-01-10 Graybug Vision, Inc. Drugs and compositions for the treatment of ocular disorders

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