GB834256A - Therapeutic bone mixture - Google Patents
Therapeutic bone mixtureInfo
- Publication number
- GB834256A GB834256A GB24808/56A GB2480856A GB834256A GB 834256 A GB834256 A GB 834256A GB 24808/56 A GB24808/56 A GB 24808/56A GB 2480856 A GB2480856 A GB 2480856A GB 834256 A GB834256 A GB 834256A
- Authority
- GB
- United Kingdom
- Prior art keywords
- bone
- plasma
- blood plasma
- clot
- animal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
Abstract
A bone mixture for application to incisions to enhance clotting and for use as a bed or filler between bone sections in general surgery and dentistry consists of pulverized viable non-human animal bone and a plasma clot as a binder for the said pulverized bone, the plasma clot substance, e.g. blood plasma, being obtained from the same species of animal, but not necessarily the same animal, as that from which the bone is obtained. Bone is preserved according to the method of Specification 827,746 by removing bone from a healthy, non-human animal body under sterile conditions and placing the removed bone in a container having therein an antibiotic such as penicillin or a sulpha drug such as sulphadiazine, and blood plasma or blood serum from the same species of animal from which the bone was removed. Bones may be from domestic animals, e.g. sheep, bovine, hogs, dogs, cats and horses. The bone so preserved is divided into small pieces, by e.g. sawing, and is then pulverized without cauterization in a grinder or mixer, and is then mixed with the plasma clot substance under sterile conditions at about 40 DEG F. In the presence of the bone, the blood plasma forms a clot, the calcium from the bone reacting with the prothrombin and thromoplastin from the blood plasma to form thrombin which in turn reacts with the fibrinogen of the blood plasma to form fibrin. A suitable gel is formed with 10 parts of bone and 1 part of plasma clot. If not used immediately, it must be maintained under sterile conditions at 40-50 DEG F. Preferably the mixture is enclosed in an osmotic membrane immersed in blood plasma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1155802XA | 1955-08-18 | 1955-08-18 | |
US834256XA | 1955-08-18 | 1955-08-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB834256A true GB834256A (en) | 1960-05-04 |
Family
ID=34922441
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB24808/56A Expired GB834256A (en) | 1955-08-18 | 1956-08-14 | Therapeutic bone mixture |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR1155802A (en) |
GB (1) | GB834256A (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3514791A (en) * | 1967-07-25 | 1970-06-02 | Charles H Sparks | Tissue grafts |
US4330891A (en) * | 1979-03-07 | 1982-05-25 | Branemark Per Ingvar | Element for implantation in body tissue, particularly bone tissue |
US5100323A (en) * | 1990-09-05 | 1992-03-31 | Impla-Med Incorporated | Dental implant |
WO2002007739A2 (en) * | 2000-07-10 | 2002-01-31 | Bertha Andras | Pharmaceutical preparation for the treatment and diagnosis of tumors and method for the preparation of the lipid free fraction of blood plasma |
US6491723B1 (en) | 1996-02-27 | 2002-12-10 | Implant Innovations, Inc. | Implant surface preparation method |
US6652765B1 (en) | 1994-11-30 | 2003-11-25 | Implant Innovations, Inc. | Implant surface preparation |
US7857987B2 (en) | 1994-11-30 | 2010-12-28 | Biomet 3I, Llc | Implant surface preparation |
US8221499B2 (en) | 1994-11-30 | 2012-07-17 | Biomet 3I, Llc | Infection-blocking dental implant |
US8251700B2 (en) | 2003-05-16 | 2012-08-28 | Biomet 3I, Llc | Surface treatment process for implants made of titanium alloy |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1180889B (en) * | 1961-03-15 | 1964-11-05 | Olin Mathieson | Process for the preparation of animal bones, cartilages, tendons or muscle skins intended for transplantation |
-
1956
- 1956-08-14 GB GB24808/56A patent/GB834256A/en not_active Expired
- 1956-08-17 FR FR1155802D patent/FR1155802A/en not_active Expired
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3514791A (en) * | 1967-07-25 | 1970-06-02 | Charles H Sparks | Tissue grafts |
US4330891A (en) * | 1979-03-07 | 1982-05-25 | Branemark Per Ingvar | Element for implantation in body tissue, particularly bone tissue |
US5100323A (en) * | 1990-09-05 | 1992-03-31 | Impla-Med Incorporated | Dental implant |
US8221499B2 (en) | 1994-11-30 | 2012-07-17 | Biomet 3I, Llc | Infection-blocking dental implant |
US6652765B1 (en) | 1994-11-30 | 2003-11-25 | Implant Innovations, Inc. | Implant surface preparation |
US7857987B2 (en) | 1994-11-30 | 2010-12-28 | Biomet 3I, Llc | Implant surface preparation |
US6491723B1 (en) | 1996-02-27 | 2002-12-10 | Implant Innovations, Inc. | Implant surface preparation method |
WO2002007739A3 (en) * | 2000-07-10 | 2002-10-10 | Andras Bertha | Pharmaceutical preparation for the treatment and diagnosis of tumors and method for the preparation of the lipid free fraction of blood plasma |
EA005415B1 (en) * | 2000-07-10 | 2005-02-24 | Андраш Берта | Pharmaceutical preparation for the treatment, prophylaxis and/or diagnosis of tumors and method for the preparation of its active component |
WO2002007739A2 (en) * | 2000-07-10 | 2002-01-31 | Bertha Andras | Pharmaceutical preparation for the treatment and diagnosis of tumors and method for the preparation of the lipid free fraction of blood plasma |
US8251700B2 (en) | 2003-05-16 | 2012-08-28 | Biomet 3I, Llc | Surface treatment process for implants made of titanium alloy |
US10227697B2 (en) | 2003-05-16 | 2019-03-12 | Biomet 3I, Llc | Surface treatment process for implants made of titanium alloy |
US11015253B2 (en) | 2003-05-16 | 2021-05-25 | Biomet 3I, Llc | Surface treatment process for implants made of titanium alloy |
Also Published As
Publication number | Publication date |
---|---|
FR1155802A (en) | 1958-05-08 |
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