GB806908A - Improvements in or relating to new aqueous solutions of monosemicarbazone of adrenochrome - Google Patents
Improvements in or relating to new aqueous solutions of monosemicarbazone of adrenochromeInfo
- Publication number
- GB806908A GB806908A GB23019/57A GB2301957A GB806908A GB 806908 A GB806908 A GB 806908A GB 23019/57 A GB23019/57 A GB 23019/57A GB 2301957 A GB2301957 A GB 2301957A GB 806908 A GB806908 A GB 806908A
- Authority
- GB
- United Kingdom
- Prior art keywords
- adrenochrome
- gamma
- beta
- monosemicarbazone
- theophylline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
An aqueous solution contains per ml. at least 0.5 mg. of adrenochrome monosemicarbozone solubilized by a 7-lower alkyl theophylline in which the lower alkyl radical contains from 2 to 6, preferably 2-4, carbon atoms and at least one hydroxyl group such as 7-hydroxyethyl, 7- beta - hydroxypropyl, 7-gamma - hydroxypropyl, 7 - dihydroxypropyl, 7 - polyhydroxybutyl, 7 - polyhydroxyamyl, 7 - polyhydroxyhexyl and preferably 7 - beta - gamma dihydroxy-n-propyl theophylline. An example describes the preparation of an aqueous solution for injection comprising 5 mg./ml. of adrenochrome monosemicarbazone solubilized by 70 mg./ml. of 7-beta, gamma-dihydroxy-n-propyl theophylline and buffered and rendered isotonic by the addition of methyl-p-hydroxybenzoate, sodium phosphate and sodium dihydrogen phosphate. U.S.A. Specifications 2,581,850, 2,575,344 and 2,506,294 are referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US806908XA | 1956-07-20 | 1956-07-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB806908A true GB806908A (en) | 1959-01-07 |
Family
ID=22158996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB23019/57A Expired GB806908A (en) | 1956-07-20 | 1957-07-19 | Improvements in or relating to new aqueous solutions of monosemicarbazone of adrenochrome |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB806908A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3244591A (en) * | 1960-08-10 | 1966-04-05 | Endo Lab | Solutions of adrenochrome monosemicarbazone in 7-dimethylaminoethyl-1, 3-dimethyl xanthine |
-
1957
- 1957-07-19 GB GB23019/57A patent/GB806908A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3244591A (en) * | 1960-08-10 | 1966-04-05 | Endo Lab | Solutions of adrenochrome monosemicarbazone in 7-dimethylaminoethyl-1, 3-dimethyl xanthine |
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