GB804232A - Improvements in or relating to the production of sennosides from folia sennae or folliculi sennae - Google Patents
Improvements in or relating to the production of sennosides from folia sennae or folliculi sennaeInfo
- Publication number
- GB804232A GB804232A GB596/57A GB59657A GB804232A GB 804232 A GB804232 A GB 804232A GB 596/57 A GB596/57 A GB 596/57A GB 59657 A GB59657 A GB 59657A GB 804232 A GB804232 A GB 804232A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sennae
- extract
- water
- per cent
- sennosides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/244—Anthraquinone radicals, e.g. sennosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Sennosides are obtained from folia sennae (senna leaves) or folliculi sennae (senna pods) by extraction with an aqueous water-soluble solvent medium, e.g. containing 5 to 50 per cent water when folia sennae and 30 to 80 per cent water when folliculi sennae is extracted, the organic constituent thereof being selected from the group consisting of aliphatic monohydric alcohols, e.g. methanol, ethanol, propanol or isopropanol, ketones, e.g. acetone, and cyclic ethers, e.g. dioxane or tetrahydrofuran, concentrating the extract, and slowly precipitating the sennosides from the concentrated extract with an aqueous or non-aqueous organic solvent selected from the said group. The extract may be filtered, concentrated to an amount 4 to 5 per cent of its volume in a vacuum of 10 to 40 mm. mercury while maintaining the temperature immediately ambient to the extract at a maximum of 40 DEG C., the concentrate agitated with an adsorption agent, e.g. talc, activated carbon, kieselguhr, active bleaching earth, bolus alba, or animal charcoal, and then filtered. The organic solvent selected from the said group is slowly added to the filtrate to precipitate the water-soluble sennosides without coagulation, the solvent concentration of the resultant solution being within the range 60 to 90 per cent in the case of a monohydric alcohol and 70 to 95 per cent in the case of any other of said organic solvents. The precipitation may be aided by addition of adsorption agents to the aqueous extract or concentrate in which case purification, e.g. filtration, of the extract or concentrate prior to the addition of the organic solvent is not necessary. The precipitate is filtered, washed with water, dissolved in excess water, and again precipitated with an adsorption agent.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE804232X | 1956-01-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB804232A true GB804232A (en) | 1958-11-12 |
Family
ID=6722062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB596/57A Expired GB804232A (en) | 1956-01-09 | 1957-01-07 | Improvements in or relating to the production of sennosides from folia sennae or folliculi sennae |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB804232A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2519253A1 (en) * | 1982-01-05 | 1983-07-08 | Madaus & Co Dr | METHOD FOR ISOLATING SENE MEDICINAL LAXATIVE EFFECT COMPOUNDS, THESE COMPOUNDS AND THEIR THERAPEUTIC USES |
-
1957
- 1957-01-07 GB GB596/57A patent/GB804232A/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2519253A1 (en) * | 1982-01-05 | 1983-07-08 | Madaus & Co Dr | METHOD FOR ISOLATING SENE MEDICINAL LAXATIVE EFFECT COMPOUNDS, THESE COMPOUNDS AND THEIR THERAPEUTIC USES |
AT376368B (en) * | 1982-01-05 | 1984-11-12 | Madaus & Co Dr | METHOD FOR PRODUCING LAXATIVE CONNECTIONS FROM SENNADROGE |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Manske et al. | THE ALKALOIDS OF LYCOPODIUM SPECIES: III. LYCOPODIUM ANNOTINUM L. | |
GB804232A (en) | Improvements in or relating to the production of sennosides from folia sennae or folliculi sennae | |
Russell et al. | The structures of tetraphyllin A and B, two new cyanoglucosides from Tetrapathaea tetrandra | |
GB1430885A (en) | Process for preparing a purified extract of quillaia bark | |
US2786781A (en) | Process of recovering nystatin | |
US2534250A (en) | Process of isolating quercitrin | |
GB929816A (en) | Aescin, and its isolation from horse chestnut extracts | |
US3920663A (en) | Method for the extraction of lysergol and ergot alkaloids from plants of the ipomoea genus | |
Oelrichs | Isolation and purification of trematoxin from Trema aspera | |
US1586116A (en) | Process for the production of glucosides of digitalis | |
US3113128A (en) | Process for the manufacture of dihydrostrophanthin | |
GB735739A (en) | Improvements in or relating to the production of heparin | |
US3057878A (en) | Process for making crystalline potassium salt of gibberellic acid | |
GB757339A (en) | Improvements in the recovery of callicrein | |
SU152276A1 (en) | Method of obtaining glyzirrhizic acid | |
GB781721A (en) | Improvements in or relating to extraction of uranium compounds | |
Manske | THE ALKALOIDS OF PAPAVERACEOUS PLANTS: XLII. DENDROMECON RIGIDA BENTH. | |
SU94292A1 (en) | The method of obtaining hyoscyamine and atropine | |
SU1057060A1 (en) | Method of extraction of gold from metal-bearing solutions | |
JPS5936604B2 (en) | Method for producing calcium salts of sennosides | |
US2099158A (en) | Process of preparing glucosides having an action on the heart obtained from oleander leaves | |
JPS6011687B2 (en) | Method for producing cathartic substances containing sennosides | |
GB1294422A (en) | A process for recovering pure manganese salts from manganese salt solutions containing organic impurities | |
GB959576A (en) | Novel saponin and process for the isolation thereof | |
GB726442A (en) | Improvements in or relating to the preparation of relaxin |