GB734117A - Preparation of a substance for the treatment of malignant tumours - Google Patents
Preparation of a substance for the treatment of malignant tumoursInfo
- Publication number
- GB734117A GB734117A GB1066852A GB1066852A GB734117A GB 734117 A GB734117 A GB 734117A GB 1066852 A GB1066852 A GB 1066852A GB 1066852 A GB1066852 A GB 1066852A GB 734117 A GB734117 A GB 734117A
- Authority
- GB
- United Kingdom
- Prior art keywords
- precipitate
- centrifuged
- few days
- solvent
- substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A substance suitable for the treatment of malignant tumours such as cancer, is prepared by treating (a) female animal blood taken during a period of from a few days before to a few days after delivery or taken during the first few days of menstruation, or (b) colostrum, undiluted with water, with an excess of a substantially non-aqueous water-miscible solvent to precipitate protein bodies containing the active substance, separating the solvent from and drying the precipitate and dispersing the dried precipitate in a neutral to slightly alkaline physiological solution. In the example, human colostrum is centrifuged to remove fat, coated to 0 DEG C. and allowed to stand. Absolute alcohol at 0 DEG C. is added slowly over 10 minutes, the mixture allowed to stand at room temperature for 50 minutes and then cooled to 0 DEG C. The precipitate is centrifuged and alcohol removed in vacuo at 45 DEG C. The precipitate is eluted with physiological saline solution containing disodium phosphate, stirred with bolus alba and centrifuged. The liquid obtained contains the active principle and can be injected, taken orally, or freeze dried to form a powder which is mixed with sterile water as required. Kaolin or fuller's earth may be used in place of bolus alba. The non-aqueous solvent may be absolute ethyl alcohol or acetone. Reference is made to the Cancer Act 1939.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1066852A GB734117A (en) | 1952-04-28 | 1952-04-28 | Preparation of a substance for the treatment of malignant tumours |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1066852A GB734117A (en) | 1952-04-28 | 1952-04-28 | Preparation of a substance for the treatment of malignant tumours |
Publications (1)
Publication Number | Publication Date |
---|---|
GB734117A true GB734117A (en) | 1955-07-27 |
Family
ID=9972078
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1066852A Expired GB734117A (en) | 1952-04-28 | 1952-04-28 | Preparation of a substance for the treatment of malignant tumours |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB734117A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3024623A1 (en) * | 1979-07-02 | 1981-01-22 | Assier De Pompignan | MEDIUM FOR EXTERNAL APPLICATION BASED ON COLOSTRUM |
-
1952
- 1952-04-28 GB GB1066852A patent/GB734117A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3024623A1 (en) * | 1979-07-02 | 1981-01-22 | Assier De Pompignan | MEDIUM FOR EXTERNAL APPLICATION BASED ON COLOSTRUM |
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