GB698767A - Readily soluble dry preparations of swelling substances - Google Patents
Readily soluble dry preparations of swelling substancesInfo
- Publication number
- GB698767A GB698767A GB16143/51A GB1614351A GB698767A GB 698767 A GB698767 A GB 698767A GB 16143/51 A GB16143/51 A GB 16143/51A GB 1614351 A GB1614351 A GB 1614351A GB 698767 A GB698767 A GB 698767A
- Authority
- GB
- United Kingdom
- Prior art keywords
- solution
- sucrose
- per cent
- freeze
- drying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13B—PRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
- C13B50/00—Sugar products, e.g. powdered, lump or liquid sugar; Working-up of sugar
- C13B50/002—Addition of chemicals or other foodstuffs
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
Abstract
Dry alimentary and medicinal preparations intended to be dissolved immediately before use and containing swelling substances which tend to agglutinate upon addition of water are made by adding a crystallizable, readily water-soluble substance such as a sugar, a salt, citric acid or urea to an aqueous solution of the swelling substance and subjecting the solution to freeze-drying. Combinations of vitamins or hormones with polyvinyl pyrrolidone, and the suitability of sucrose, glucose or sorbite in preparations for parenteral application are referred to. Examples are concerned with freeze-drying a 2 1/2 per cent aqueous gelatine solution with an addition of 4 per cent of sucrose, calculated on the weight of the solution, and a 2 1/2 per cent aqueous gelatine solution with an addition of 5 per cent of sodium chloride, calculated on the weight of the solution, and the freeze-drying, in ampoules containing 2.6 ml., of an aqueous solution of 25,000 I.U. of the hormone of the anterior pituitary gland, 2.5 g. of polyvinyl pyrrolidone and 4.5 g. of sucrose per 100 ml., and in ampoules containing 1.5 ml., of an aqueous solution of 10,000 units of the circulatory hormone callicrein, 9 g. of sucrose and 5 g. of polyvinyl pyrrolidone per 100 ml.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE698767X | 1950-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB698767A true GB698767A (en) | 1953-10-21 |
Family
ID=6608238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB16143/51A Expired GB698767A (en) | 1950-07-06 | 1951-07-06 | Readily soluble dry preparations of swelling substances |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB698767A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149042A (en) * | 1959-07-09 | 1964-09-15 | Colgate Palmolive Co | Hair preparations |
| WO1993023017A1 (en) | 1992-05-06 | 1993-11-25 | Janssen Pharmaceutica, Inc. | Pharmaceutical and other dosage forms |
-
1951
- 1951-07-06 GB GB16143/51A patent/GB698767A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149042A (en) * | 1959-07-09 | 1964-09-15 | Colgate Palmolive Co | Hair preparations |
| WO1993023017A1 (en) | 1992-05-06 | 1993-11-25 | Janssen Pharmaceutica, Inc. | Pharmaceutical and other dosage forms |
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