GB690463A - Alkyl riboflavin phosphates and process for the manufacture thereof - Google Patents
Alkyl riboflavin phosphates and process for the manufacture thereofInfo
- Publication number
- GB690463A GB690463A GB21144/51A GB2114451A GB690463A GB 690463 A GB690463 A GB 690463A GB 21144/51 A GB21144/51 A GB 21144/51A GB 2114451 A GB2114451 A GB 2114451A GB 690463 A GB690463 A GB 690463A
- Authority
- GB
- United Kingdom
- Prior art keywords
- riboflavin
- alkyl
- phosphates
- manufacture
- mono
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 title abstract 7
- -1 Alkyl riboflavin phosphates Chemical class 0.000 title abstract 5
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 title abstract 5
- 235000019192 riboflavin Nutrition 0.000 title abstract 5
- 229960002477 riboflavin Drugs 0.000 title abstract 5
- 239000002151 riboflavin Substances 0.000 title abstract 5
- 229910019142 PO4 Inorganic materials 0.000 title abstract 3
- 235000021317 phosphate Nutrition 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 229950001574 riboflavin phosphate Drugs 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- FVTCRASFADXXNN-SCRDCRAPSA-N flavin mononucleotide Chemical compound OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O FVTCRASFADXXNN-SCRDCRAPSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65618—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system, e.g. flavins or analogues
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
Abstract
The invention comprises alkyl riboflavin phosphates, the alkyl group or groups whereof each contain not more than five carbon atoms e.g. mono and diethyl and mono and dimethyl riboflavin phosphates and their preparation by reacting riboflavin with an alkyl chlorophosphate. The reaction may be effected by adding one or two mols. of an alkanol to phosphorus oxychloride with the subsequent addition of riboflavin. The alkyl riboflavin phosphate may be hydrolysed to riboflavin phosphate, e.g. with aqueous hydrochloric acid.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US690463XA | 1951-01-26 | 1951-01-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB690463A true GB690463A (en) | 1953-04-22 |
Family
ID=22086375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB21144/51A Expired GB690463A (en) | 1951-01-26 | 1951-09-07 | Alkyl riboflavin phosphates and process for the manufacture thereof |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB690463A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5095115A (en) * | 1989-09-14 | 1992-03-10 | Basf Aktiengesellschaft | Preparation of riboflavin 5'-phosphate (fmn) and its sodium salt in a lactone |
-
1951
- 1951-09-07 GB GB21144/51A patent/GB690463A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5095115A (en) * | 1989-09-14 | 1992-03-10 | Basf Aktiengesellschaft | Preparation of riboflavin 5'-phosphate (fmn) and its sodium salt in a lactone |
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