GB578682A - Improvements in the process of making sulphaguanidine - Google Patents

Improvements in the process of making sulphaguanidine

Info

Publication number
GB578682A
GB578682A GB7726/44A GB772644A GB578682A GB 578682 A GB578682 A GB 578682A GB 7726/44 A GB7726/44 A GB 7726/44A GB 772644 A GB772644 A GB 772644A GB 578682 A GB578682 A GB 578682A
Authority
GB
United Kingdom
Prior art keywords
alkali
acylsulphanilylguanidine
acetylsulphanilylguanidine
hydrolysis
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7726/44A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of GB578682A publication Critical patent/GB578682A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/64—X and Y being nitrogen atoms, e.g. N-sulfonylguanidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Sulphanilylguanidines are prepared by subjecting an acylsulphanilylguanidine such as N4-acetylsulphanilylguanidine to hydrolysis in an aqueous solution of an alkali metal hydroxide at a temperature within the range 50-100 DEG C., using an amount of alkali corresponding to 50-100 parts by weight of alkali per 100 parts by weight of acylsulphanilylguanidine. It is stated that in the operation of the process of this invention temperature control is important, and the preferred temperature range is 65-85 DEG C. The control of the amount of alkali is also an important feature. Examples are given of the hydrolysis of N4-acetylsulphanilylguanidine under the above conditions, using sodium hydroxide as the hydrolysing agent.
GB7726/44A 1943-05-01 1944-04-25 Improvements in the process of making sulphaguanidine Expired GB578682A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US578682XA 1943-05-01 1943-05-01

Publications (1)

Publication Number Publication Date
GB578682A true GB578682A (en) 1946-07-08

Family

ID=22013215

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7726/44A Expired GB578682A (en) 1943-05-01 1944-04-25 Improvements in the process of making sulphaguanidine

Country Status (1)

Country Link
GB (1) GB578682A (en)

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