GB546596A - A process for the manufacture of quaternary ammonium compounds - Google Patents

A process for the manufacture of quaternary ammonium compounds

Info

Publication number
GB546596A
GB546596A GB1752740A GB1752740A GB546596A GB 546596 A GB546596 A GB 546596A GB 1752740 A GB1752740 A GB 1752740A GB 1752740 A GB1752740 A GB 1752740A GB 546596 A GB546596 A GB 546596A
Authority
GB
United Kingdom
Prior art keywords
pyridine
malonic acid
ammonium chloride
chloride
quaternary ammonium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1752740A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Products Ltd
Original Assignee
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Products Ltd filed Critical Roche Products Ltd
Priority to GB1752740A priority Critical patent/GB546596A/en
Publication of GB546596A publication Critical patent/GB546596A/en
Expired legal-status Critical Current

Links

Abstract

546,596. Crotonic acid betaine compounds. ROCHE PRODUCTS, Ltd., BERGEL, F., COHEN, A., and HINDLEY, N. C. Dec. 10, 1940, No. 17527. [Class 2 (iii)] Crotonic acid betaine compounds and quaternary ammonium compounds of similar constitution are prepared by the condensation of malonic acid with a quaternary ammonium salt of the general formula where R, R<SP>1</SP>, and R" are alkyl aryl; or aralkyl groups and X is halogen. The condensation is preferably carried out in the presence of a base such as pyridine. In examples (1) a reaction mixture comprising malonic acid, anhydrous pyridine and the hydrate of trimethylethylal-ammonium chloride is heated on the water bath, evaporated to dryness, and purified by. fractional precipitation to give crotonic acid betaine chloride. (2) Triethylethylalammonium chloride, malonic acid and dry pyridine are heated on a hot water bath and worked up as in example (1) and the product purified by formation of a reineckate to form γ-carboxyallyl-triethyl ammonium chloride. (3) Trimethyl-#-propional-ammonium chloride, malonic acid and dry 'pyridine are treated as in example (1) to produce #-carboxy-# γ-#- butenyltrimethyl ammonium chloride.
GB1752740A 1940-12-10 1940-12-10 A process for the manufacture of quaternary ammonium compounds Expired GB546596A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1752740A GB546596A (en) 1940-12-10 1940-12-10 A process for the manufacture of quaternary ammonium compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1752740A GB546596A (en) 1940-12-10 1940-12-10 A process for the manufacture of quaternary ammonium compounds

Publications (1)

Publication Number Publication Date
GB546596A true GB546596A (en) 1942-07-21

Family

ID=10096732

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1752740A Expired GB546596A (en) 1940-12-10 1940-12-10 A process for the manufacture of quaternary ammonium compounds

Country Status (1)

Country Link
GB (1) GB546596A (en)

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