GB515412A - Processes of preparing derivatives of aromatic amino-sulfamids - Google Patents
Processes of preparing derivatives of aromatic amino-sulfamidsInfo
- Publication number
- GB515412A GB515412A GB6329/38A GB632938A GB515412A GB 515412 A GB515412 A GB 515412A GB 6329/38 A GB6329/38 A GB 6329/38A GB 632938 A GB632938 A GB 632938A GB 515412 A GB515412 A GB 515412A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sulphonamide
- aminobenzene
- give
- acid
- aminobenzenesulphonamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
515,412. Sulphonamide compounds. RICHTER GEDEON VEGYESZETI GYAR R.T. Feb. 28, 1938, Nos. 6329 and 6330. Void. Convention dates, April 29, 1937, and Jan. 31, 1938. [Class 2(iii)] Aminobenzene-sulphonamides are acylated with aliphatic or aromatic dicarboxylic acids to give products of the formula in which R represents an aliphatic or aromatic residue and X stands for hydrogen, alkyl or aryl, which two latter groups may be split off by saponification. The acid products, which may be converted into salts, possess therapeutic properties. According to the examples (1) p-aminobenzene-sulphonamide is melted with adipic acid to give p-adipinylaminobenzene sulphonamide ; (2) p-aminobenzene-sulphonamide is heated with succinic acid in aqueous solution and produces p-succinylaminobenzenesulphonamide; the product may be converted into its salts with quinine and with phenolazoalpha:alpha - diaminopyridine ; (3) p-aminobenzene - sulphonamide is dissolved in aqueous sodium carbonate and treated with malonic acid monochloride, Whereby p - malonylaminobenzene - sulphonamide is formed ; (4) p-aminobenzenesulphonamide is heated in aqueous solution with phthalic anhydride 'to give p-phthalylaminobenzene-sulphonamide ; (5) p-aminobenzenesulphonamide is boiled with diethyl oxalate and the resulting mono-ester saponified with caustic soda solution to yield p-oxalylaminobenzene-sulphonamide.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU515412X | 1937-04-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB515412A true GB515412A (en) | 1939-12-04 |
Family
ID=10979444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6329/38A Expired GB515412A (en) | 1937-04-29 | 1938-02-28 | Processes of preparing derivatives of aromatic amino-sulfamids |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB515412A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2422170A (en) * | 1943-07-05 | 1947-06-10 | Sharp & Dohme Inc | Sulfanilylsulfanilamide |
| US2423108A (en) * | 1943-07-07 | 1947-07-01 | Sharp & Dohme Inc | N-carboxyacyl-metanilamides |
| US2533033A (en) * | 1943-02-18 | 1950-12-05 | Sharp & Dohme Inc | N4-succinylsulfanilamidodiazines |
-
1938
- 1938-02-28 GB GB6329/38A patent/GB515412A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2533033A (en) * | 1943-02-18 | 1950-12-05 | Sharp & Dohme Inc | N4-succinylsulfanilamidodiazines |
| US2422170A (en) * | 1943-07-05 | 1947-06-10 | Sharp & Dohme Inc | Sulfanilylsulfanilamide |
| US2423108A (en) * | 1943-07-07 | 1947-07-01 | Sharp & Dohme Inc | N-carboxyacyl-metanilamides |
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