GB369062A - Improvements in anti-leprotic drugs - Google Patents

Improvements in anti-leprotic drugs

Info

Publication number
GB369062A
GB369062A GB1414431A GB1414431A GB369062A GB 369062 A GB369062 A GB 369062A GB 1414431 A GB1414431 A GB 1414431A GB 1414431 A GB1414431 A GB 1414431A GB 369062 A GB369062 A GB 369062A
Authority
GB
United Kingdom
Prior art keywords
esters
acids
alcohol
mixed
alcohols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1414431A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HUMPHREY PAGET
Wellcome Foundation Ltd
Original Assignee
HUMPHREY PAGET
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HUMPHREY PAGET, Wellcome Foundation Ltd filed Critical HUMPHREY PAGET
Priority to GB1414431A priority Critical patent/GB369062A/en
Publication of GB369062A publication Critical patent/GB369062A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The fatty acids, mainly chaulmoogric and hydnocarpic acids, obtained by saponification of the oils of flacourtiaceous seeds are purified by crystallization from alcohol and esterified with aliphatic, hydroaromatic or aromaticaliphatic alcohols to form the corresponding esters. Reduction of these esters gives the corresponding mixed alcohols, which may then be treated with acylating agents to produce their acyl esters. Flacourtiaceous plants mentioned are Taraktogenos kurzii, Hydnocarpus wightiana, Hydnocarpus anthelmintica, Carpotroche brasiliensis and Caloncoba echinata. The products are useful therapeutically. According to the examples, (1) the total fatty acids derived from the said oils are dissolved in hot alcohol and the crystalline acids which separate out on cooling are filtered off, washed with alcohol and dried; the mixed acids are then converted into their ethyl, cyclohexanyl, benzyl, thymyl, methyl and cinnamyl esters; (2) the ethyl esters of the mixed crystalline acids are reduced with sodium and alcohol; (3) the mixed alcohols prepared according to (2) are heated with benzoyl and cinnamoyl chlorides to give the corresponding esters. Specifications 1984/09 and 311,236, [both in Class 2 (iii), Dyes &c.], are referred to.
GB1414431A 1931-05-13 1931-05-13 Improvements in anti-leprotic drugs Expired GB369062A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1414431A GB369062A (en) 1931-05-13 1931-05-13 Improvements in anti-leprotic drugs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1414431A GB369062A (en) 1931-05-13 1931-05-13 Improvements in anti-leprotic drugs

Publications (1)

Publication Number Publication Date
GB369062A true GB369062A (en) 1932-03-17

Family

ID=10035814

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1414431A Expired GB369062A (en) 1931-05-13 1931-05-13 Improvements in anti-leprotic drugs

Country Status (1)

Country Link
GB (1) GB369062A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011028214A1 (en) * 2009-09-02 2011-03-10 Momentive Performance Materials Inc. Silicone modified fatty acids, method of preparation and usage thereof
US9492372B2 (en) 2007-06-27 2016-11-15 Natura Cosmeticos S.A. Process for preparing sapucainha oil or butter, cosmetic or pharmaceutical composition and use of the sapucainha oil or butter

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9492372B2 (en) 2007-06-27 2016-11-15 Natura Cosmeticos S.A. Process for preparing sapucainha oil or butter, cosmetic or pharmaceutical composition and use of the sapucainha oil or butter
WO2011028214A1 (en) * 2009-09-02 2011-03-10 Momentive Performance Materials Inc. Silicone modified fatty acids, method of preparation and usage thereof
US8846843B2 (en) 2009-09-02 2014-09-30 Momentive Performance Materials Inc. Silicone modified fatty acids, method of preparation and usage thereof
US8975357B2 (en) 2009-09-02 2015-03-10 Natura Inovacao E Tecnologia De Produtos Ltda. Silicone modified fatty acids, method of preparation and usage thereof

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