GB288628A - Process for the manufacture of hydroxypyridine compounds - Google Patents

Process for the manufacture of hydroxypyridine compounds

Info

Publication number
GB288628A
GB288628A GB10037/28A GB1003728A GB288628A GB 288628 A GB288628 A GB 288628A GB 10037/28 A GB10037/28 A GB 10037/28A GB 1003728 A GB1003728 A GB 1003728A GB 288628 A GB288628 A GB 288628A
Authority
GB
United Kingdom
Prior art keywords
nitropyridine
groups
acid
hydroxypyridine
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB10037/28A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schering Kahlbaum AG
Original Assignee
Schering Kahlbaum AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Kahlbaum AG filed Critical Schering Kahlbaum AG
Publication of GB288628A publication Critical patent/GB288628A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

288,628. Schering-Kahlbaum Akt.- Ges., (Assignees of Rõth, C.). April 14, 1927, [Convention date]. 2-Hydroxypyridines and their derivatives are obtained by treating a 2-halogenpyridine which has no hydrolysable group in the 5-position or a derivative thereof with an alkaline or acid hydrolyzing agent, in the presence or absence of a solvent or diluent. Suitable starting materials are 2-halogenpyridines which may contain 3- or 5- arsinic acid groups, or nitro groups, or further halogen groups. The products possess therapeutic properties. Examples are given of the treatment of 2-chloropyridine with caustic potash to give 2-hydroxypyridine, and of both the hydrochloric acid and caustic soda saponification of 2- chloro-5-nitropyridine to from 2-bydroxy-5-nitropyridine. Specification 288,629 is referred to.
GB10037/28A 1927-04-14 1928-04-03 Process for the manufacture of hydroxypyridine compounds Expired GB288628A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE288628X 1927-04-14

Publications (1)

Publication Number Publication Date
GB288628A true GB288628A (en) 1929-07-03

Family

ID=6059650

Family Applications (1)

Application Number Title Priority Date Filing Date
GB10037/28A Expired GB288628A (en) 1927-04-14 1928-04-03 Process for the manufacture of hydroxypyridine compounds

Country Status (1)

Country Link
GB (1) GB288628A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040355A1 (en) * 1997-03-07 1998-09-17 Zeneca Limited Process for preparing 2-hydroxy-6-trifluoromethylpyridine
WO2000014068A1 (en) * 1998-09-03 2000-03-16 Syngenta Limited Chemical process for preparing 2-hydroxy-6-trifluoromethylpyridine

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998040355A1 (en) * 1997-03-07 1998-09-17 Zeneca Limited Process for preparing 2-hydroxy-6-trifluoromethylpyridine
US5973159A (en) * 1997-03-07 1999-10-26 Zeneca Limited Chemical process
WO2000014068A1 (en) * 1998-09-03 2000-03-16 Syngenta Limited Chemical process for preparing 2-hydroxy-6-trifluoromethylpyridine
US6143899A (en) * 1998-09-03 2000-11-07 Zeneca Limited Chemical process

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