GB2564444B - Liquid pharmaceutical composition of flecainide - Google Patents

Liquid pharmaceutical composition of flecainide Download PDF

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Publication number
GB2564444B
GB2564444B GB1711091.7A GB201711091A GB2564444B GB 2564444 B GB2564444 B GB 2564444B GB 201711091 A GB201711091 A GB 201711091A GB 2564444 B GB2564444 B GB 2564444B
Authority
GB
United Kingdom
Prior art keywords
flecainide
pharmaceutical composition
liquid pharmaceutical
liquid
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1711091.7A
Other versions
GB201711091D0 (en
GB2564444A (en
Inventor
Patel Kamlesh
Maganbhai Patel Sanjaykumar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syri Ltd
Original Assignee
Syri Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syri Ltd filed Critical Syri Ltd
Priority to GB1711091.7A priority Critical patent/GB2564444B/en
Publication of GB201711091D0 publication Critical patent/GB201711091D0/en
Publication of GB2564444A publication Critical patent/GB2564444A/en
Application granted granted Critical
Publication of GB2564444B publication Critical patent/GB2564444B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4458Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB1711091.7A 2017-07-10 2017-07-10 Liquid pharmaceutical composition of flecainide Active GB2564444B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1711091.7A GB2564444B (en) 2017-07-10 2017-07-10 Liquid pharmaceutical composition of flecainide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1711091.7A GB2564444B (en) 2017-07-10 2017-07-10 Liquid pharmaceutical composition of flecainide

Publications (3)

Publication Number Publication Date
GB201711091D0 GB201711091D0 (en) 2017-08-23
GB2564444A GB2564444A (en) 2019-01-16
GB2564444B true GB2564444B (en) 2020-09-16

Family

ID=59676702

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1711091.7A Active GB2564444B (en) 2017-07-10 2017-07-10 Liquid pharmaceutical composition of flecainide

Country Status (1)

Country Link
GB (1) GB2564444B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019183470A2 (en) 2018-03-22 2019-09-26 Incarda Therapeutics, Inc. A novel method to slow ventricular rate
US11020384B2 (en) 2019-08-01 2021-06-01 Incarda Therapeutics, Inc. Antiarrhythmic formulation
AU2020323594B2 (en) * 2019-08-01 2022-02-03 Incarda Therapeutics, Inc. Antiarrhythmic formulation

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
American Journal of Health-System Pharmacy, vol. 53, no. 18, 1996, pages 2179-2184 *
European Journal of Clinical Pharmacology, vol. 60, no. 10, 2004, pages 693-701 *
MEDA PHARMACEUTICALS, 2017, Technical Information Leaflet for Patients Tambocor 10 mg/mL solution for injection or infusion, www.medicines.org.uk, [online], Available from https://www.medicines.org.uk/emc/files/pil.1544.pdf [Accessed 28 March 2018] *
ORTHO-McNEIL-JANSSEN PHARMACEUTICALS, 2009, Propulsid - FDA prescribing information, side effects and uses, www.drugs.com, [online], Available from https://www.drugs.com/pro/propulsid.html [Accessed 28 March 2018] *
U.S. Pharmacopeia, 2010, "Vehicle for Oral Solution, Sugar Free", www.pharmacopeia.cn, [online], Available from https://web.archive.org/web/20101127111557/http://www.pharmacopeia.cn/v29240/usp29nf24s0_m383.html [Accessed 28 March 2018] *
U.S. Pharmacopeia, 2014, "Flecainide Acetate Oral Suspension", www.drugfuture.com, [online], Available from https://web.archive.org/web/20140911000345/http://www.drugfuture.com/Pharmacopoeia/USP35/data/v35300/usp35nf30s0_m3930.html [Accessed 28 March 2018] *
University of Michigan College of Pharmacy, 2016, "Michigan Collaborative Standardization of Compounded Oral Liquids: Flecainide Acetate", www.mipedscompounds.org, [online], *

Also Published As

Publication number Publication date
GB201711091D0 (en) 2017-08-23
GB2564444A (en) 2019-01-16

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