GB2525709B - Optimized multiple reaction monitoring or single ion recording method - Google Patents

Optimized multiple reaction monitoring or single ion recording method

Info

Publication number
GB2525709B
GB2525709B GB1501848.4A GB201501848A GB2525709B GB 2525709 B GB2525709 B GB 2525709B GB 201501848 A GB201501848 A GB 201501848A GB 2525709 B GB2525709 B GB 2525709B
Authority
GB
United Kingdom
Prior art keywords
recording method
multiple reaction
reaction monitoring
single ion
ion recording
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1501848.4A
Other versions
GB201501848D0 (en
GB2525709A (en
Inventor
Raymond Green Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201401881A external-priority patent/GB201401881D0/en
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Priority to GB1501848.4A priority Critical patent/GB2525709B/en
Publication of GB201501848D0 publication Critical patent/GB201501848D0/en
Publication of GB2525709A publication Critical patent/GB2525709A/en
Application granted granted Critical
Publication of GB2525709B publication Critical patent/GB2525709B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8624—Detection of slopes or peaks; baseline correction
    • G01N30/8644—Data segmentation, e.g. time windows
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
GB1501848.4A 2014-02-04 2015-02-04 Optimized multiple reaction monitoring or single ion recording method Active GB2525709B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1501848.4A GB2525709B (en) 2014-02-04 2015-02-04 Optimized multiple reaction monitoring or single ion recording method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201401881A GB201401881D0 (en) 2014-02-04 2014-02-04 Optimized multiple reaction monitoring or single ion recording method
GB1501848.4A GB2525709B (en) 2014-02-04 2015-02-04 Optimized multiple reaction monitoring or single ion recording method

Publications (3)

Publication Number Publication Date
GB201501848D0 GB201501848D0 (en) 2015-03-18
GB2525709A GB2525709A (en) 2015-11-04
GB2525709B true GB2525709B (en) 2018-07-11

Family

ID=52706380

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1501848.4A Active GB2525709B (en) 2014-02-04 2015-02-04 Optimized multiple reaction monitoring or single ion recording method

Country Status (1)

Country Link
GB (1) GB2525709B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020535599A (en) * 2017-09-29 2020-12-03 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド Assessment of MRM peak purity using isotope-selective MS / MS
US10892152B1 (en) * 2019-08-27 2021-01-12 Thermo Finnigan Llc Adjustable dwell time for SRM acquisition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006189279A (en) * 2005-01-05 2006-07-20 Shimadzu Corp Chromatograph mass spectrometer
US20070114374A1 (en) * 2005-10-20 2007-05-24 Prest Harry F Dynamic adjustment of ion monitoring periods
US20100276586A1 (en) * 2009-04-30 2010-11-04 Senko Michael W Intrascan data dependency

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006189279A (en) * 2005-01-05 2006-07-20 Shimadzu Corp Chromatograph mass spectrometer
US20070114374A1 (en) * 2005-10-20 2007-05-24 Prest Harry F Dynamic adjustment of ion monitoring periods
US20100276586A1 (en) * 2009-04-30 2010-11-04 Senko Michael W Intrascan data dependency

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Agilent Technologies, May 2010, "Agilent 6400 Series Triple Quad LC/MS System " [Online]. Available from http://www.agilent.com/cs/library/usermanuals/Public/g3335-90086_qqq_quickstart.pdf [Accessed 25th August 2015] *

Also Published As

Publication number Publication date
GB201501848D0 (en) 2015-03-18
GB2525709A (en) 2015-11-04

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