GB2440081A - A method of measuring the glomerular filtration rate of a human or animal patient a self-use kit for providing blood samples - Google Patents
A method of measuring the glomerular filtration rate of a human or animal patient a self-use kit for providing blood samples Download PDFInfo
- Publication number
- GB2440081A GB2440081A GB0721595A GB0721595A GB2440081A GB 2440081 A GB2440081 A GB 2440081A GB 0721595 A GB0721595 A GB 0721595A GB 0721595 A GB0721595 A GB 0721595A GB 2440081 A GB2440081 A GB 2440081A
- Authority
- GB
- United Kingdom
- Prior art keywords
- patient
- human
- filtration rate
- glomerular filtration
- measuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
- A61B5/1405—Devices for taking blood samples
- A61B5/1411—Devices for taking blood samples by percutaneous method, e.g. by lancet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
- A61B5/1405—Devices for taking blood samples
- A61B5/1427—Multiple blood sampling, e.g. at periodic or pre-established intervals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150305—Packages specially adapted for piercing devices or blood sampling devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150358—Strips for collecting blood, e.g. absorbent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15142—Devices intended for single use, i.e. disposable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15146—Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15101—Details
- A61B5/15103—Piercing procedure
- A61B5/15107—Piercing being assisted by a triggering mechanism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Physiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
A method of measuring glomerular filtration rate in a human or animal patient comprising: (i) intravenously administering a known amount of filtration marker to the patient at a known time; (ii) taking a sample of capillary blood from the patient at a known time after administration and absorbing a droplet of blood on an absorbent substrate to form a blood spot on the substrate; (iii) causing or allowing the blood spot to dry on the substrate; (iv) removing a portion of said substrate, said portion having a predetermined, substantially constant volume, and being substantially uniformly impregnated with the blood spot; (v) extracting an analyte from the portion; (vi) quantitating the amount of said filtration marker in said analyte; and (vii) determining the glomerular filtration rate of the patient from the quantitated amount of said filtration marker.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1005968A GB2466737B (en) | 2005-04-18 | 2006-04-18 | A self use kit for providing blood samples for use in measuring glomerular filtration rate of a patient |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0507838.1A GB0507838D0 (en) | 2005-04-18 | 2005-04-18 | A method of measuring the glomerular filtration rate of an human or animal patient, a self-use kit for providing blood samples for use in measuring glomerular |
PCT/GB2006/001426 WO2006111741A1 (en) | 2005-04-18 | 2006-04-18 | A method of measuring the glomerular filtration rate of a human or animal patient, a self-use kit for providing blood samples for use in measuring the glomerular filtration rate of a patient, and a method of collecting timed samples of capillary blood from a patient |
Publications (3)
Publication Number | Publication Date |
---|---|
GB0721595D0 GB0721595D0 (en) | 2007-12-12 |
GB2440081A true GB2440081A (en) | 2008-01-16 |
GB2440081B GB2440081B (en) | 2010-08-25 |
Family
ID=34630888
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB0507838.1A Ceased GB0507838D0 (en) | 2005-04-18 | 2005-04-18 | A method of measuring the glomerular filtration rate of an human or animal patient, a self-use kit for providing blood samples for use in measuring glomerular |
GB0721595A Active GB2440081B (en) | 2005-04-18 | 2006-04-18 | A method of measuring the glomerular filtration rate of a patient and a self-use kit for providing blood samples |
GB1005968A Active GB2466737B (en) | 2005-04-18 | 2006-04-18 | A self use kit for providing blood samples for use in measuring glomerular filtration rate of a patient |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB0507838.1A Ceased GB0507838D0 (en) | 2005-04-18 | 2005-04-18 | A method of measuring the glomerular filtration rate of an human or animal patient, a self-use kit for providing blood samples for use in measuring glomerular |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1005968A Active GB2466737B (en) | 2005-04-18 | 2006-04-18 | A self use kit for providing blood samples for use in measuring glomerular filtration rate of a patient |
Country Status (2)
Country | Link |
---|---|
GB (3) | GB0507838D0 (en) |
WO (1) | WO2006111741A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101679525B (en) * | 2007-03-26 | 2013-06-19 | 诺瓦提斯公司 | Predictive renal safety biomarkers and biomarker signatures to monitor kidney function |
US9033898B2 (en) | 2010-06-23 | 2015-05-19 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
US9295417B2 (en) | 2011-04-29 | 2016-03-29 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
US9041541B2 (en) | 2010-01-28 | 2015-05-26 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
WO2010101620A2 (en) | 2009-03-02 | 2010-09-10 | Seventh Sense Biosystems, Inc. | Systems and methods for creating and using suction blisters or other pooled regions of fluid within the skin |
WO2011065972A2 (en) * | 2009-11-24 | 2011-06-03 | Seventh Sense Biosystems, Inc. | Patient-enacted sampling technique |
US8775095B2 (en) | 2010-06-18 | 2014-07-08 | Roche Diagnostics Operations, Inc. | Methods and apparatus for decentralized diabetes monitoring |
EP2593014B1 (en) | 2010-07-16 | 2015-11-04 | Seventh Sense Biosystems, Inc. | Low-pressure environment for fluid transfer devices |
US20120039809A1 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
EP2637562B1 (en) | 2010-11-09 | 2016-01-27 | Seventh Sense Biosystems, Inc. | Systems and interfaces for blood sampling |
ES2597081T3 (en) | 2011-04-29 | 2017-01-13 | Seventh Sense Biosystems, Inc. | Delivery and / or reception of fluids |
EP2702406B1 (en) | 2011-04-29 | 2017-06-21 | Seventh Sense Biosystems, Inc. | Plasma or serum production and removal of fluids under reduced pressure |
US20130158468A1 (en) | 2011-12-19 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
WO2016025429A1 (en) * | 2014-08-15 | 2016-02-18 | The Johns Hopkins University | Precise estimation of glomerular filtration rate from multiple biomarkers |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4908202A (en) * | 1988-02-02 | 1990-03-13 | Cassella Aktiengesellschaft | Use of 2-oxo-1-pyrrolidineacetamide for the determination of the glomerular filtration rate in humans |
WO2004064637A1 (en) * | 2003-01-23 | 2004-08-05 | Epsom & St Helier University Hospitals Nhs Trust | A lancet holding device |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4731726A (en) * | 1986-05-19 | 1988-03-15 | Healthware Corporation | Patient-operated glucose monitor and diabetes management system |
US5518006A (en) * | 1994-08-09 | 1996-05-21 | International Technidyne Corp. | Blood sampling device |
US5951492A (en) * | 1996-05-17 | 1999-09-14 | Mercury Diagnostics, Inc. | Methods and apparatus for sampling and analyzing body fluid |
US5989198A (en) * | 1997-05-30 | 1999-11-23 | Mayo Foundation For Medical Education And Research | Use of capillary electrophoresis to determine glomerular filtration rate using iothalamate |
US20020055176A1 (en) * | 2000-11-08 | 2002-05-09 | Ray Robert A. | Diagnostic assay system |
US6474694B1 (en) * | 2001-06-05 | 2002-11-05 | Moore North America, Inc. | Medical test form |
US20030195435A1 (en) * | 2002-04-12 | 2003-10-16 | Williams Arthur G. | Method and apparatus for collecting and transporting capillary blood samples for diagnostic and research evaluation |
-
2005
- 2005-04-18 GB GBGB0507838.1A patent/GB0507838D0/en not_active Ceased
-
2006
- 2006-04-18 GB GB0721595A patent/GB2440081B/en active Active
- 2006-04-18 WO PCT/GB2006/001426 patent/WO2006111741A1/en active Application Filing
- 2006-04-18 GB GB1005968A patent/GB2466737B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4908202A (en) * | 1988-02-02 | 1990-03-13 | Cassella Aktiengesellschaft | Use of 2-oxo-1-pyrrolidineacetamide for the determination of the glomerular filtration rate in humans |
WO2004064637A1 (en) * | 2003-01-23 | 2004-08-05 | Epsom & St Helier University Hospitals Nhs Trust | A lancet holding device |
Non-Patent Citations (5)
Title |
---|
Acta Paediatrica (2005), Vol 94, pp 19-23, "Measurement of renal function in patients...", Kleinert et al * |
Clinical Chemistry (1987), Vol 33, pp 1643-1644, "Capillary blood, dried on filter paper,...", Lampe et al * |
Diabetic Medicine (2001), Vol 18, pp 116-120, "Iohexol as a marker of glomerular...", Pucci et al * |
Kidney International (2006), Vol 69, pp 1272-1275, "Development of an outpatient...", Niculescu-Duvaz et al * |
Renal Failure (1998), Vol 20, pp 277-284, "Iohexol plasma clearance in determining...", Pucci et al * |
Also Published As
Publication number | Publication date |
---|---|
GB2466737B (en) | 2010-10-13 |
GB2466737A (en) | 2010-07-07 |
WO2006111741A1 (en) | 2006-10-26 |
GB0507838D0 (en) | 2005-05-25 |
GB201005968D0 (en) | 2010-05-26 |
GB2440081B (en) | 2010-08-25 |
GB0721595D0 (en) | 2007-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20170418 |
|
S28 | Restoration of ceased patents (sect. 28/pat. act 1977) |
Free format text: APPLICATION FILED |
|
S28 | Restoration of ceased patents (sect. 28/pat. act 1977) |
Free format text: RESTORATION ALLOWED Effective date: 20180511 |