GB2387844B - Separation of impurities from a crude mixture of citalopram - Google Patents

Separation of impurities from a crude mixture of citalopram

Info

Publication number
GB2387844B
GB2387844B GB0315852A GB0315852A GB2387844B GB 2387844 B GB2387844 B GB 2387844B GB 0315852 A GB0315852 A GB 0315852A GB 0315852 A GB0315852 A GB 0315852A GB 2387844 B GB2387844 B GB 2387844B
Authority
GB
United Kingdom
Prior art keywords
citalopram
impurities
separation
crude mixture
crude
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB0315852A
Other versions
GB0315852D0 (en
GB2387844A (en
Inventor
Chava Satyanarayana
Ramana Rao Chunchu Venkata
Basu Abbineni Jyothi
Babu Bobepudi Hari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mylan Laboratories Ltd
Original Assignee
Matrix Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0204607.6A external-priority patent/GB0204607D0/en
Application filed by Matrix Laboratories Ltd filed Critical Matrix Laboratories Ltd
Publication of GB0315852D0 publication Critical patent/GB0315852D0/en
Publication of GB2387844A publication Critical patent/GB2387844A/en
Application granted granted Critical
Publication of GB2387844B publication Critical patent/GB2387844B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB0315852A 2002-02-27 2002-05-03 Separation of impurities from a crude mixture of citalopram Expired - Fee Related GB2387844B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0204607.6A GB0204607D0 (en) 2002-02-27 2002-02-27 Process
GB0210225A GB2375763B (en) 2002-02-27 2002-05-03 Process

Publications (3)

Publication Number Publication Date
GB0315852D0 GB0315852D0 (en) 2003-08-13
GB2387844A GB2387844A (en) 2003-10-29
GB2387844B true GB2387844B (en) 2005-05-11

Family

ID=28676482

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0315853A Expired - Fee Related GB2387596B (en) 2002-02-27 2002-05-03 Process
GB0315852A Expired - Fee Related GB2387844B (en) 2002-02-27 2002-05-03 Separation of impurities from a crude mixture of citalopram

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB0315853A Expired - Fee Related GB2387596B (en) 2002-02-27 2002-05-03 Process

Country Status (1)

Country Link
GB (2) GB2387596B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003057132A2 (en) * 2002-01-07 2003-07-17 Sun Pharmaceutical Industries Limited Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136193A (en) * 1976-01-14 1979-01-23 Kefalas A/S Anti-depressive substituted 1-dimethylaminopropyl-1-phenyl phthalans
GB2357762A (en) * 2000-03-13 2001-07-04 Lundbeck & Co As H Preparation of Crystalline Base or Salts of Citalopram
GB2376945A (en) * 2001-06-27 2002-12-31 Cipla Ltd Citalopram preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1015416E (en) * 1997-07-08 2002-03-28 Lundbeck & Co As H METHOD FOR THE PRODUCTION OF CITALOPRAM
WO2003057132A2 (en) * 2002-01-07 2003-07-17 Sun Pharmaceutical Industries Limited Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136193A (en) * 1976-01-14 1979-01-23 Kefalas A/S Anti-depressive substituted 1-dimethylaminopropyl-1-phenyl phthalans
GB2357762A (en) * 2000-03-13 2001-07-04 Lundbeck & Co As H Preparation of Crystalline Base or Salts of Citalopram
GB2376945A (en) * 2001-06-27 2002-12-31 Cipla Ltd Citalopram preparation

Also Published As

Publication number Publication date
GB2387596B (en) 2004-02-11
GB0315852D0 (en) 2003-08-13
GB0315853D0 (en) 2003-08-13
GB2387596A (en) 2003-10-22
GB2387844A (en) 2003-10-29

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20100503