GB2342920A - In vivo modification of galactomannans in guar by expression of udp-galactose epimerase antisense rna - Google Patents

In vivo modification of galactomannans in guar by expression of udp-galactose epimerase antisense rna

Info

Publication number
GB2342920A
GB2342920A GB9927197A GB9927197A GB2342920A GB 2342920 A GB2342920 A GB 2342920A GB 9927197 A GB9927197 A GB 9927197A GB 9927197 A GB9927197 A GB 9927197A GB 2342920 A GB2342920 A GB 2342920A
Authority
GB
United Kingdom
Prior art keywords
galactose
mannose
udp
galactomannans
guar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB9927197A
Other versions
GB9927197D0 (en
GB2342920B (en
Inventor
Morten Joersboe
Janne Brunstedt
Steen Guldager Petersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DuPont Nutrition Biosciences ApS
Danisco US Inc
Original Assignee
Danisco AS
Danisco US Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco AS, Danisco US Inc filed Critical Danisco AS
Publication of GB9927197D0 publication Critical patent/GB9927197D0/en
Publication of GB2342920A publication Critical patent/GB2342920A/en
Application granted granted Critical
Publication of GB2342920B publication Critical patent/GB2342920B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)

Abstract

An <I>in vivo</I> modification process is described. The process affects the mannose-to-galactose ratio of either an organism (or part thereof) capable of producing a mannose/galactose containing compound or of a mannose/galactose containing compound thereof. The <I>in vivo</I> modification process comprises expressing a nucleotide sequence that has an effect on: (a) the mannose-to-galactose ratio of mannose and galactose components of a mannose/galactose containing compound; and/or (b) the mannose-to-galactose ratio of mannose and galactose precursors for a mannose/galactose containing compound; and wherein the nucleotide sequence is antisense to at least a part of the gene for a UDP-galactose epimerase enzyme.
GB9927197A 1997-05-28 1998-05-27 In vivo modification of galactomannans in guar by expression of udp-galactose epimerase antisense rna Expired - Fee Related GB2342920B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710990.4A GB9710990D0 (en) 1997-05-28 1997-05-28 Modification process
PCT/IB1998/000891 WO1998054335A1 (en) 1997-05-28 1998-05-27 In vivo modification of galactomannans in guar by expression of udp-galactose epimerase antisense rna

Publications (3)

Publication Number Publication Date
GB9927197D0 GB9927197D0 (en) 2000-01-12
GB2342920A true GB2342920A (en) 2000-04-26
GB2342920B GB2342920B (en) 2001-08-15

Family

ID=10813167

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB9710990.4A Pending GB9710990D0 (en) 1997-05-28 1997-05-28 Modification process
GB9927197A Expired - Fee Related GB2342920B (en) 1997-05-28 1998-05-27 In vivo modification of galactomannans in guar by expression of udp-galactose epimerase antisense rna

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB9710990.4A Pending GB9710990D0 (en) 1997-05-28 1997-05-28 Modification process

Country Status (10)

Country Link
EP (1) EP0983369A1 (en)
JP (1) JP2002500515A (en)
KR (1) KR20010012962A (en)
CN (1) CN1264428A (en)
AU (1) AU733483B2 (en)
BR (1) BR9809493A (en)
CA (1) CA2291449A1 (en)
GB (2) GB9710990D0 (en)
NZ (1) NZ500951A (en)
WO (1) WO1998054335A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9710990D0 (en) * 1997-05-28 1997-07-23 Danisco Modification process
ITPD980169A1 (en) * 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl AMIDES OF HYALURONIC ACID AND ITS DERIVATIVES AND PROCESS FOR THEIR PREPARATION.
US6992236B1 (en) 1999-02-10 2006-01-31 E. I. Du Pont De Nemours And Company Plant UDP-glucose epimerases
EP1151115A2 (en) * 1999-02-10 2001-11-07 E.I. Du Pont De Nemours And Company Plant udp-glucose epimerases
GB9914210D0 (en) 1999-06-17 1999-08-18 Danisco Promoter
US7265265B2 (en) 2002-11-14 2007-09-04 Pioneer Hi-Bred International, Inc. Genes for galactomannan production in plants and methods of use
ITPD20050056A1 (en) 2005-03-02 2006-09-03 Fidia Farmaceutici AMIDID DERIVATIVES OF HYALURONIC ACID IN OSTEOARTROSI
US7585818B2 (en) 2005-05-10 2009-09-08 Halliburton Energy Services, Inc. Nonnatural galactomannans and methods of use
JP2010520766A (en) 2007-03-09 2010-06-17 コーニング インコーポレイテッド Three-dimensional gum matrix for cell culture, production method and method of use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012876A1 (en) * 1989-04-24 1990-11-01 Aktieselskabet De Danske Spritfabrikker (Danisco A/S) POTATO α-AMYLASE GENES
WO1997020937A2 (en) * 1995-12-04 1997-06-12 Danisco A/S Modification process

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9710990D0 (en) * 1997-05-28 1997-07-23 Danisco Modification process

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012876A1 (en) * 1989-04-24 1990-11-01 Aktieselskabet De Danske Spritfabrikker (Danisco A/S) POTATO α-AMYLASE GENES
WO1997020937A2 (en) * 1995-12-04 1997-06-12 Danisco A/S Modification process

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Arch. Biochem. & Biophysic Vol. 327 (1) 1996. Dormann P et.al. *
Carbohydrate Polymers Vol. 12 (2) 1990. Bulpin P V et.al. pages 155-168 *
EMBL OSAD4300 Acc No. D21120 1993. Uchimiya H *
EMBL PS31544 Acc No. U31544 1996. Slocum R D et.al. *
Plant J. Vo. 13 (5) 1998. Dormann P et.al. 641-52 *
Planta No. 178 1989. Edwards et.al. page 41 et. seq. *

Also Published As

Publication number Publication date
NZ500951A (en) 2001-09-28
AU7446398A (en) 1998-12-30
CA2291449A1 (en) 1998-12-03
WO1998054335A1 (en) 1998-12-03
JP2002500515A (en) 2002-01-08
GB9710990D0 (en) 1997-07-23
EP0983369A1 (en) 2000-03-08
KR20010012962A (en) 2001-02-26
AU733483B2 (en) 2001-05-17
CN1264428A (en) 2000-08-23
GB9927197D0 (en) 2000-01-12
BR9809493A (en) 2000-06-20
GB2342920B (en) 2001-08-15

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20030527