GB2293604B - Dermal fibroblast cells containing muscle-specific DNA and the use of dermal fibroblast cells in the treatment of muscular disorders - Google Patents

Dermal fibroblast cells containing muscle-specific DNA and the use of dermal fibroblast cells in the treatment of muscular disorders

Info

Publication number
GB2293604B
GB2293604B GB9518887A GB9518887A GB2293604B GB 2293604 B GB2293604 B GB 2293604B GB 9518887 A GB9518887 A GB 9518887A GB 9518887 A GB9518887 A GB 9518887A GB 2293604 B GB2293604 B GB 2293604B
Authority
GB
United Kingdom
Prior art keywords
fibroblast cells
dermal fibroblast
treatment
specific dna
muscular disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9518887A
Other versions
GB2293604A (en
GB9518887D0 (en
Inventor
Diana Joan Watt
Joao Carlos Bettencourt Relvas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Publication of GB9518887D0 publication Critical patent/GB9518887D0/en
Publication of GB2293604A publication Critical patent/GB2293604A/en
Application granted granted Critical
Publication of GB2293604B publication Critical patent/GB2293604B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656—Adult fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB9518887A 1994-09-20 1995-09-15 Dermal fibroblast cells containing muscle-specific DNA and the use of dermal fibroblast cells in the treatment of muscular disorders Expired - Fee Related GB2293604B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9419048A GB9419048D0 (en) 1994-09-20 1994-09-20 Treatment of muscular disorders

Publications (3)

Publication Number Publication Date
GB9518887D0 GB9518887D0 (en) 1995-11-15
GB2293604A GB2293604A (en) 1996-04-03
GB2293604B true GB2293604B (en) 1996-09-11

Family

ID=10761695

Family Applications (2)

Application Number Title Priority Date Filing Date
GB9419048A Pending GB9419048D0 (en) 1994-09-20 1994-09-20 Treatment of muscular disorders
GB9518887A Expired - Fee Related GB2293604B (en) 1994-09-20 1995-09-15 Dermal fibroblast cells containing muscle-specific DNA and the use of dermal fibroblast cells in the treatment of muscular disorders

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB9419048A Pending GB9419048D0 (en) 1994-09-20 1994-09-20 Treatment of muscular disorders

Country Status (6)

Country Link
EP (1) EP0783568A1 (en)
JP (1) JPH10505756A (en)
AU (1) AU694957B2 (en)
CA (1) CA2198379A1 (en)
GB (2) GB9419048D0 (en)
WO (1) WO1996009373A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9715085D0 (en) * 1997-07-18 1997-09-24 Jahoda Amanda J Gene therapy vehicle
IT1296439B1 (en) * 1997-11-14 1999-06-25 San Raffaele Centro Fond GENETICALLY MODIFIED MYOGENIC PRECURSORS AND THEIR USE IN GENE AND CELL THERAPY
IT1299201B1 (en) * 1998-05-08 2000-02-29 San Raffaele Centro Fond GENETICALLY MODIFIED FIBROBLASTS AND THEIR USE
CN107920503A (en) * 2015-06-11 2018-04-17 伊利诺伊大学理事会 The method of muscular dystrophy chimeric cell and treatment muscular dystrophy
CN110291190B (en) 2016-12-28 2024-06-04 京都府公立大学法人 Skeletal muscle cells and methods of inducing same
AU2020282836A1 (en) * 2019-05-31 2022-01-06 Figene, Llc Fibroblast therapy for treatment of duchenne muscular dystrophy
US20230340416A1 (en) * 2020-07-14 2023-10-26 Figene, Llc Augmentation of fibroblast therapeutic activity by complement blockade and/or inhibition

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015863A1 (en) * 1989-06-13 1990-12-27 The Board Of Directors Of The Leland Stanford Junior University Isolation growth and differentiation of human muscle cells
WO1993003768A1 (en) * 1991-08-22 1993-03-04 The Board Of Trustees Of The Leland Stanford Junior University Isolation, growth, differentiation and genetic engineering of human muscle cells
WO1993009236A1 (en) * 1991-11-06 1993-05-13 Baylor College Of Medicine Myogenic vector systems
WO1993021347A1 (en) * 1992-04-10 1993-10-28 Fox Chase Cancer Center Transcription control element for increasing gene expression in myoblasts
WO1993024151A1 (en) * 1992-05-29 1993-12-09 The General Hospital Corporation Arterial introduction of myoblasts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219740A (en) * 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
EP0378576B1 (en) * 1987-09-11 1995-01-18 Whitehead Institute For Biomedical Research Transduced fibroblasts and uses therefor
AU7312891A (en) * 1990-02-12 1991-09-03 Board Of Regents, The University Of Texas System Satellite cell proliferation in adult skeletal muscle

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015863A1 (en) * 1989-06-13 1990-12-27 The Board Of Directors Of The Leland Stanford Junior University Isolation growth and differentiation of human muscle cells
WO1993003768A1 (en) * 1991-08-22 1993-03-04 The Board Of Trustees Of The Leland Stanford Junior University Isolation, growth, differentiation and genetic engineering of human muscle cells
WO1993009236A1 (en) * 1991-11-06 1993-05-13 Baylor College Of Medicine Myogenic vector systems
WO1993021347A1 (en) * 1992-04-10 1993-10-28 Fox Chase Cancer Center Transcription control element for increasing gene expression in myoblasts
WO1993024151A1 (en) * 1992-05-29 1993-12-09 The General Hospital Corporation Arterial introduction of myoblasts

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J.Cell Science 1995,108(1),207-218 *

Also Published As

Publication number Publication date
JPH10505756A (en) 1998-06-09
GB2293604A (en) 1996-04-03
EP0783568A1 (en) 1997-07-16
AU694957B2 (en) 1998-08-06
WO1996009373A1 (en) 1996-03-28
AU3481695A (en) 1996-04-09
CA2198379A1 (en) 1996-03-28
GB9419048D0 (en) 1994-11-09
GB9518887D0 (en) 1995-11-15

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20010915