GB2281036A - Topical compositions containing polybutenes - Google Patents

Topical compositions containing polybutenes Download PDF

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Publication number
GB2281036A
GB2281036A GB9316107A GB9316107A GB2281036A GB 2281036 A GB2281036 A GB 2281036A GB 9316107 A GB9316107 A GB 9316107A GB 9316107 A GB9316107 A GB 9316107A GB 2281036 A GB2281036 A GB 2281036A
Authority
GB
United Kingdom
Prior art keywords
skin
polybutenes
homologues
tissues
volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB9316107A
Other versions
GB9316107D0 (en
Inventor
Michael David Townsend
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agri Tech Inc
Agri Technology
Original Assignee
Agri Tech Inc
Agri Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agri Tech Inc, Agri Technology filed Critical Agri Tech Inc
Priority to GB9316107A priority Critical patent/GB2281036A/en
Publication of GB9316107D0 publication Critical patent/GB9316107D0/en
Publication of GB2281036A publication Critical patent/GB2281036A/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/24—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients to enhance the sticking of the active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Dentistry (AREA)
  • Toxicology (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)

Abstract

Adhesion of active ingredients to the skin is enhanced by including polybutene (or its homologues) in the preparation. Udder grease, insect repelling gel and a composition for treating bruising, cuts etc. are exemplified.

Description

A SYSTEM FOR THE ENHANCEMENT OF THE ADHESION (F ACTIVE ( AND OTHER ) CHEMICAL COMPOUNDS/ELLEMENTS TO THE SKIN AND/OR TISSUES OF ANIMALS.
This invention relates to @ system for the enhancement of the adhesion of active ( and other ) chemical compounds/elements to the skin and/or tissues or animals for the purposes of treatment end/or prevention of veterinery ( medical ) conditions, illnesses, diseases, deficiencies or depletion., and for protective, general veterinary treatment and nutritional purposes.
Many problems arise in the care of domestic livestock and pets, and wild animals ( where appropriate - iea- zoological gardens, wildlife parks and game parks etc. ), where it is important to the maintainence of the good health of the animal that one or more chemical componds and/or elements should be applied to the skin nd/or tiouec of the animal. A prime of example of such is the necessity to apply fly repellant (s) to the udders of dairy ( and suckler ) cows during their dry ( non-lactating ) periods in order to prevent the spread of the udder disease(s) commonly known as HASTITIS, which are spread from cow to cow by means of flying insects.
MASTITIS infections cc-only ceuse loss ( by the cows infected ) of the ability to produce milk and ( frequently ) the death of the cow eo infected - which, in c.rtsin circumstances, can ontail a lose of 10 30 per cent of the potential productivity (milk production) of a deiry herd in any one year.
It is, therefore, of economic fnporturcs to those business interests which incur the care of animals/livestock that any chemical compound and/or element used for such protective/treatment/maintainance of good health of the animals should adhere in an officacecus manner to the skin and/or tissues of the particular animal (s) to which it is applied, and, at the site where it is applied for such Z period of time as to successfully achieve its purpose and to be economically viable in general usage.
According to the prevent invention there is provided a method whereby preparations of active and/or other chemical compounds and/or elements can be made to adhere successfcully to animal skin and/or ti@sues at those paticular sites to which they are so applied; and to so remain for such periods of time that the purpose of use of such comical compounds and/or elements may be successfully achieved within the parameters of economic viability.
According to the present invention the organic-chemical, hydrocarbonbased chemical group - PDLYBUTENES and/or their homologues - may be used to enhance and increase the adhesive properties of active ( and other ) chemical compounds and/or elements by means of inclusion into the formulation of, and mixing with, the preparation to be used; either alone or in conjunction and combination with other chemical compounds and/or elements which may be either of organic or inorganic classification.
The advantages to the use of polybutenes and/or their homologues for such purposes is that: 1. A@hesion of the chemical compounds and/or elements is improved.
2. Compatibility with most chemical compounds/elements is readily and easily achieved.
3. Polybutanes and/or their homologues possess very low toxicity to mammals end/or other animels; and by safely be used in the presence of unprotected living tissue, body fluids end/or food substences with minimal problems in respect to toxicity or irritability.
EXAMPLES.
EXAMPLE No. 1.
An insect-repellant gel made by mixing together 85 % volume/volume of POL VBUTENE plus 15 % volume/volume of N,N-DIETHYL-META-TOLUAMIDE plus colouring agent, and sold as en adhering insect repellent for application to the udders of dry ( non-lactatsting ) cows to help to prevent the spread of mastitis infections, which are normally vectored by flying insects.
EXAMPLE NO. 2.
An udder gresse, for application to the udders of cows, made by mixing 25 % volume/volume of POLYBUTENE into a suitable udder grease formulation ( yellow or white soft paraffin plus active ingredients ); end demonstrating ennanced adhesion in respect to udder greases made only of paraffins plus active ingredients - particularly in respect to adhesion in warm/hot/wet weather conditions.
EXAMPLE No. 3.
A synthetic skin spray/spray bandage for covering and protecting cuts, bruises and abrssions in animal skin ( and to enhance healing and to help to limit the development of infections ), made by mixing 25 % volume/volume of POLYBUTENE with 70 % volume/volume of synthetic scrylate resin solution ( in a auitable organic solvent ) or collodion, plus 5 % volume/volume of anti-bacterial agents plus colouring agents.
It is emphasized that the invention includes, but is not limited to, the examples enumerated above.
The invention includes all all sohesive formulations including and involving the use and/or utilisation of polybutenes and polybutens homologues for application to animel skin and/or tissues.

Claims (4)

  1. CLAIMS.
    What we claim i@:- 1. An adhesive system for the enhancement of the adhesion of active ( or other ) chemical compounds and/or elements to the skin and/or tissues of animals ( either domestic or other ) for whatever purpose is, or might be, roquired.
  2. 2. The utilisation of the orgenic hydrocerbon chemical group - polybutenes and/or their homologues for the purposes described and cleimed in CLAIM No. 1.
  3. 3. An adhesive system for the application of chemical compounds and/or el@ments to the skin and/or tissues of animale in which polybutenes and/or polybutene homologues are included in the finished product formulation and/or specification.
  4. 4. An achesive syatem for use on, and application to, the skin and/or tissues of animals, in which polybutenes and/or polybutene homologues are included in the finished product formulation and/or specific@tion.
GB9316107A 1993-08-02 1993-08-02 Topical compositions containing polybutenes Withdrawn GB2281036A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB9316107A GB2281036A (en) 1993-08-02 1993-08-02 Topical compositions containing polybutenes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9316107A GB2281036A (en) 1993-08-02 1993-08-02 Topical compositions containing polybutenes

Publications (2)

Publication Number Publication Date
GB9316107D0 GB9316107D0 (en) 1993-09-15
GB2281036A true GB2281036A (en) 1995-02-22

Family

ID=10739918

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9316107A Withdrawn GB2281036A (en) 1993-08-02 1993-08-02 Topical compositions containing polybutenes

Country Status (1)

Country Link
GB (1) GB2281036A (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1586258A (en) * 1976-12-24 1981-03-18 Bayer Ag Agents having a residual action for combating animal ectoparasites
EP0055023A2 (en) * 1980-12-18 1982-06-30 E.R. Squibb & Sons, Inc. Antiseptic containing adhesive composition
GB2140019A (en) * 1983-05-04 1984-11-21 Alza Corp Matrix composition for transdermal drug delivery systems
JPS6051109A (en) * 1983-08-31 1985-03-22 Nitto Electric Ind Co Ltd Rubber pressure-sensitive adhesive plaster
JPS6277314A (en) * 1985-09-30 1987-04-09 Nitto Electric Ind Co Ltd Medicinal pharmaceutical
JPH03120213A (en) * 1989-10-03 1991-05-22 Nitto Denko Corp Percutaneous absorption preparation
WO1991016085A1 (en) * 1990-04-16 1991-10-31 Alza Corporation Polyisobutylene adhesives for transdermal devices

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1586258A (en) * 1976-12-24 1981-03-18 Bayer Ag Agents having a residual action for combating animal ectoparasites
EP0055023A2 (en) * 1980-12-18 1982-06-30 E.R. Squibb & Sons, Inc. Antiseptic containing adhesive composition
GB2140019A (en) * 1983-05-04 1984-11-21 Alza Corp Matrix composition for transdermal drug delivery systems
JPS6051109A (en) * 1983-08-31 1985-03-22 Nitto Electric Ind Co Ltd Rubber pressure-sensitive adhesive plaster
JPS6277314A (en) * 1985-09-30 1987-04-09 Nitto Electric Ind Co Ltd Medicinal pharmaceutical
JPH03120213A (en) * 1989-10-03 1991-05-22 Nitto Denko Corp Percutaneous absorption preparation
WO1991016085A1 (en) * 1990-04-16 1991-10-31 Alza Corporation Polyisobutylene adhesives for transdermal devices

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
WPI Accession No. 85-107360/18 & JP 60051109 A *
WPI Accession No. 87-139139/20 & JP 62077314 A *
WPI Accession No. 91-196393/27 & JP 03120213 A *

Also Published As

Publication number Publication date
GB9316107D0 (en) 1993-09-15

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WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)