GB2236185B - Process,specimen and device for making an analyte available for an investigation - Google Patents

Process,specimen and device for making an analyte available for an investigation

Info

Publication number
GB2236185B
GB2236185B GB9018334A GB9018334A GB2236185B GB 2236185 B GB2236185 B GB 2236185B GB 9018334 A GB9018334 A GB 9018334A GB 9018334 A GB9018334 A GB 9018334A GB 2236185 B GB2236185 B GB 2236185B
Authority
GB
United Kingdom
Prior art keywords
investigation
specimen
making
analyte available
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB9018334A
Other versions
GB9018334D0 (en
GB2236185A (en
Inventor
Franz Hillenkamp
Michael Karas
Ulrich Giessmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Finnigan MAT GmbH
Original Assignee
Finnigan MAT GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4017805A external-priority patent/DE4017805C2/en
Application filed by Finnigan MAT GmbH filed Critical Finnigan MAT GmbH
Publication of GB9018334D0 publication Critical patent/GB9018334D0/en
Publication of GB2236185A publication Critical patent/GB2236185A/en
Application granted granted Critical
Publication of GB2236185B publication Critical patent/GB2236185B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/22Devices for withdrawing samples in the gaseous state
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/04Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N2001/045Laser ablation; Microwave vaporisation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/74Optical detectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/95Detectors specially adapted therefor; Signal analysis

Landscapes

  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • Electrochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
GB9018334A 1989-08-22 1990-08-21 Process,specimen and device for making an analyte available for an investigation Expired - Lifetime GB2236185B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3927602 1989-08-22
DE3937165 1989-11-08
DE4017805A DE4017805C2 (en) 1989-08-22 1990-06-01 Method, preparation and device for providing an analyte for an examination

Publications (3)

Publication Number Publication Date
GB9018334D0 GB9018334D0 (en) 1990-10-03
GB2236185A GB2236185A (en) 1991-03-27
GB2236185B true GB2236185B (en) 1994-03-23

Family

ID=27200055

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9018334A Expired - Lifetime GB2236185B (en) 1989-08-22 1990-08-21 Process,specimen and device for making an analyte available for an investigation

Country Status (1)

Country Link
GB (1) GB2236185B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071003B2 (en) 1993-05-28 2006-07-04 Baylor College Of Medicine Surface-enhanced laser desorption/Ionization for desorption and detection of analytes
US7074619B2 (en) 1993-05-28 2006-07-11 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071610A (en) 1993-11-12 2000-06-06 Waters Investments Limited Enhanced resolution matrix-laser desorption and ionization TOF-MS sample surface
CA2205040C (en) * 1993-11-12 2006-10-17 Joseph A. Jarrell Enhanced resolution maldi tof-ms sample surface
GB9518429D0 (en) * 1995-09-08 1995-11-08 Pharmacia Biosensor A rapid method for providing kinetic and structural data in molecular interaction analysis
DE19618032C2 (en) * 1996-05-04 2000-04-13 Bruker Daltonik Gmbh Prepared Maldi sample carriers that can be stored
EP1173878B1 (en) 1999-04-27 2011-04-06 Bio-Rad Laboratories, Inc. Probes for a gas phase ion spectrometer
DE10018788B4 (en) 2000-04-15 2004-02-26 Bruker Daltonik Gmbh Processing proteins from gels for mass spectrometric analysis
US20060051741A1 (en) 2002-10-04 2006-03-09 Protosera Inc. Plate for mass spectrometry, process for preparing the same and use thereof
DE10112386B4 (en) * 2001-03-15 2007-08-02 Bruker Daltonik Gmbh Time-of-flight mass spectrometer with multiplex operation
GB0809768D0 (en) * 2008-05-29 2008-07-09 Univ Sheffield Hallam Improvements to mass spectrometry
WO2018092271A1 (en) 2016-11-18 2018-05-24 株式会社島津製作所 Ion analyzer

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Anal. Chem. 1984, 56, 2-7 *
Anal. Chem. 1985, 57, 353-358 *
Anal. Chem. 1989, 61, 1906-1910 *
Anal. Chem. 1989, 61, 1911-1915 *
J. Chromatogr. Biomed. Appl. 1986, 383(1), 51-60 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071003B2 (en) 1993-05-28 2006-07-04 Baylor College Of Medicine Surface-enhanced laser desorption/Ionization for desorption and detection of analytes
US7074619B2 (en) 1993-05-28 2006-07-11 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US7294515B2 (en) 1993-05-28 2007-11-13 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US7413909B2 (en) * 1993-05-28 2008-08-19 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US7491549B2 (en) 1993-05-28 2009-02-17 Baylor College Of Medicine Apparatus for desorption and ionization of analytes
US8748193B2 (en) 1993-05-28 2014-06-10 Baylor College Of Medicine Apparatus for desorption and ionization of analytes

Also Published As

Publication number Publication date
GB9018334D0 (en) 1990-10-03
GB2236185A (en) 1991-03-27

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Expiry date: 20100820