GB2083036A - Aminothiol derivatives, their preparation and use, and compositions containing them - Google Patents

Aminothiol derivatives, their preparation and use, and compositions containing them Download PDF

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Publication number
GB2083036A
GB2083036A GB8126304A GB8126304A GB2083036A GB 2083036 A GB2083036 A GB 2083036A GB 8126304 A GB8126304 A GB 8126304A GB 8126304 A GB8126304 A GB 8126304A GB 2083036 A GB2083036 A GB 2083036A
Authority
GB
United Kingdom
Prior art keywords
branched
linear
group
derivative
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB8126304A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Continental Pharma Inc
Original Assignee
Continental Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma Inc filed Critical Continental Pharma Inc
Publication of GB2083036A publication Critical patent/GB2083036A/en
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB8126304A 1980-08-29 1981-08-28 Aminothiol derivatives, their preparation and use, and compositions containing them Withdrawn GB2083036A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU82738A LU82738A1 (fr) 1980-08-29 1980-08-29 Derives d'aminothiols,leur preparation et utilisation ainsi que compositions contenant ces derives

Publications (1)

Publication Number Publication Date
GB2083036A true GB2083036A (en) 1982-03-17

Family

ID=19729472

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8126304A Withdrawn GB2083036A (en) 1980-08-29 1981-08-28 Aminothiol derivatives, their preparation and use, and compositions containing them

Country Status (18)

Country Link
JP (1) JPS5798255A (fi)
AU (1) AU7465481A (fi)
BE (1) BE890116A (fi)
DE (1) DE3133293A1 (fi)
DK (1) DK382281A (fi)
ES (1) ES505037A0 (fi)
FI (1) FI812640L (fi)
FR (1) FR2489325A1 (fi)
GB (1) GB2083036A (fi)
GR (1) GR74348B (fi)
IL (1) IL63664A0 (fi)
IT (1) IT1137642B (fi)
LU (1) LU82738A1 (fi)
NL (1) NL8103993A (fi)
NO (1) NO812944L (fi)
PT (1) PT73593B (fi)
SE (1) SE8104958L (fi)
ZA (1) ZA815912B (fi)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154296A2 (en) * 1984-03-07 1985-09-11 Sandoz Ag Hair growth stimulating agents and their use
EP0163119A2 (en) * 1984-04-30 1985-12-04 The Johns Hopkins University Brain imaging radiopharmaceuticals

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2505870A (en) * 1947-05-09 1950-05-02 Phillips Petroleum Co Secondary and tertiary alkylthiol amines and their production
US3337625A (en) * 1961-09-18 1967-08-22 Lilly Co Eli Amino-acetylenic compounds
US3312732A (en) * 1962-02-28 1967-04-04 Monsanto Res Corp Aminoalkyl aminoalkanethiols
US3356730A (en) * 1964-11-25 1967-12-05 Monsanto Res Corp Mercaptoalkyl oxyalkyl amines
GB1138738A (en) * 1966-12-01 1969-01-01 Eastman Kodak Co Aziridine derivatives
US3622676A (en) * 1968-11-20 1971-11-23 Constance Anthony D Alonzo Smoking suppression
CA992105A (en) * 1970-03-26 1976-06-29 Exxon Research And Engineering Company Polythioethers formed by anionic ring opening of episulfides
BE789629A (fr) * 1971-10-05 1973-04-03 Sandoz Sa Nouveaux derives de la pleuromutiline, leur preparation et leurapplication en therapeutique
CH632906A5 (en) * 1976-08-09 1982-11-15 Givaudan & Cie Sa Use of bifunctional N,S-compounds as flavourings

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154296A2 (en) * 1984-03-07 1985-09-11 Sandoz Ag Hair growth stimulating agents and their use
EP0154296A3 (en) * 1984-03-07 1987-01-21 Sandoz Ag Hair growth stimulating agents and their use
EP0163119A2 (en) * 1984-04-30 1985-12-04 The Johns Hopkins University Brain imaging radiopharmaceuticals
EP0163119A3 (en) * 1984-04-30 1986-10-08 The Johns Hopkins University Brain imaging radiopharmaceuticals

Also Published As

Publication number Publication date
NL8103993A (nl) 1982-03-16
PT73593A (fr) 1981-09-01
BE890116A (fr) 1982-03-01
GR74348B (fi) 1984-06-26
NO812944L (no) 1982-03-01
IT1137642B (it) 1986-09-10
LU82738A1 (fr) 1982-05-10
PT73593B (fr) 1982-11-10
SE8104958L (sv) 1982-03-01
DK382281A (da) 1982-03-01
AU7465481A (en) 1982-03-04
ES8307735A1 (es) 1983-08-16
DE3133293A1 (de) 1982-04-08
IL63664A0 (en) 1981-11-30
ES505037A0 (es) 1983-08-16
FR2489325A1 (fr) 1982-03-05
ZA815912B (en) 1982-08-25
FI812640L (fi) 1982-03-01
JPS5798255A (en) 1982-06-18
IT8123611A0 (it) 1981-08-24

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)