GB2060401A - Tube assembly for use in liquid dispensing apparatus - Google Patents

Abstract

A tube assembly for use in an infusion apparatus has a T-tube (9) of which the limb tube serves as a closed reservoir (8) for liquid and is closed at its free end to provide, in use, an air space above the liquid in the reservoir, a first tube 6 connected to one arm of the T-tube for conveying to the reservoir liquid to be infused and a second tube 13 for conveying liquid from the reservoir to the infusion needle; both tubes are of resiliently deformable material. <IMAGE>

Description

SPECIFICATION Tube assembly for use in liquid dispensing apparatus This invention relates to a tube assembly for use in liquid dispensing apparatus, in particular though not exclusively for use in medical or veterinary infusion apparatus.

Infusion apparatus for infusing liquids such as glucose, saline solution or drugs, into patients is widely used. In one method of controlling infusion, the rate of production of drips in a drip forming chamber which is connected between the liquid storage bottle of the drip set and an infusion needle inserted into the patient, is maintained at a constant value, using for example a roller clamp on the drip line. In controlling the infusion rate in this way, it is assumed that the volume of each drip is constant.

However, factors such as temperature variations, changes in viscosity of the liquid, hydrostatic pressure variations, and pressure variations during infusion can affect the volume of each drip. Whilst these effects in many cases are unimportant, such as when infusing glucose or saline solution, this drip volume variation can in certain circumstances prove unsatisfactory, especially where administering drugs which are particularly potent or expensive. Thus, in some instances it is necessary to effect volumetric control.

For this purpose, one standard piece of equipment comprises a storage reservoir administration set, and a cam-operated reciprocating syringe provided with non-return valves in the supply and outlet/delivery lines, the infusion rate on the delivery stroke of the syringe plunger being controlled by the gradual displacement of the plunger. The syringe with the non-return valves is made as a disposable injection-moulded cartridge. Over a period of use, the cost of the cartridges needed becomes quite considerable. Moreover, the infusion pressure is generally significantly higher than the minimum pressure required for infusion into the patent, and this can be undesirable. Additionally, it can be dif ficult to prime the syringe and this can result in air becoming trapped in the syringe.To avoid pumping air into the patient with possibly fatal consequences, an air bubble detector is used to monitor the liquid dispensed through the delivery line to the patient, the detector switching off the equipment in the event of an air bubble being detected in the delivery line.

This all adds to the cost and complexity of the equipment.

Our copending patent application No. 7937848 describes and claims apparatus for dispensing a predetermined quantity of liquid; in one aspect the apparatus comprises a reservoir for liquid, means including a positive displacement pump operative to admit liquid to the reservoir to a predetermined datum level, and dispensing means including a positive displacement peristaltic pump, operative to pump liquid out of the reservoir until the liquid level therein falls from said datum level to a predetermined lower level, wherein the two pumps are provided with a common drive arrangement which comprises a single, reversible-drive prime mover coupled to each pump via a respective gearbox and a respective clutch, the clutches being so arranged that for one of the two directions in which the prime mover can drive, one of the clutches transmits drive while the other is disengaged, and vice versa for the other direction of drive. The change in level corresponds to the said predetermined quantity of liquid.

This apparatus provides an especially convenient way of delivering a predetermined quantity of liquid.

Furthermore, when used as part of infusion equipment, because of the operating properties of peristaltic pumps, the pump pressure can easily be set just above the minimum infusion pressure necessary.

According to one aspect of the present invention, there is provided a tube assembly for use in infusion apparatus, comprising a T-tube of which the limb tube constitutes a reservoir for liquid and is closed at its free end to provide, in use, an air space above liquid in the reservoir, a first tube connected to one arm tube of the T-tube for conveying to the reservoir liquid to be infused, and a second tube connected at one end to the other arm of the T-tube and at the other end to a third tube for conveying liquid from the reservoir to an infusion needle, the first and second tubes each being made of material which can be resiliently deformed to close at least partially the passage within the tube.The first and second tubes are intended to be installed as the pumping tubes of respective peristaltic positive displacement pumps so that the operative movable parts (e.g. rollers or fingers) are arranged to exert a pumping action on liquid in the first and second tubes. Alternatively, however, if an adequate liquid supply pressure exists to the first tube, the first and second tubes can be provided with respective clamps so as to control selectively the flow through these tubes.

Such a tube assembly can be made extremely cheap to produce and therefore even over a lengthy period of time involving the use of a large number of fresh tube assemblies, the total outlay is relatively low.

The liquid tube can be closed with a filter serving as pressure relief means for relieving excess pressure from the air space while preventing entry of any contaminants into the reservoir.

According to another aspect of the present invention, there is provided apparatus for dispensing a predetermined quantity of liquid, comprising a T-tube of which the limb tube constitutes a reservoir for liquid and is closed at its free end to provide, in use, an air space above liquid in the reservoir, a first tube connected to one arm tube of the T-tube for conveying to the reservoir liquid to be infused and made of resiliently deformable material to enable the passage within the tube to be closed at least partially, a second tube made of a material having the same deformation property as the first tube and connected at one end to the other arm of the T-tube and at the other end to a third tube; leading to an infusion needle, for conveying liquid from the reservoir to the needle, a first peristaltic pump operative to exert a pumping action on said first tube, a first level detector arranged to render said first peristaltic pump inoperative once liquid has been pumped into the reservoir to a predetermined datum level, a second peristaltic pump operative to exert a pumping action on said second tube, a second level detector arranged to render the second pump inoperative when liquid in the reservoir has fallen from said datum level to a predetermined lower level, and a controller arranged to control operation of the two pumps cyclically so as to deliver a predetermined quantity of liquid from the infusion needle at regular intervals.

For a better understanding of the invention and to show how the same may be carried into effect, reference will now be made, by way of example, to the accompanying drawing which shows diagrammatically a tube assembly in accordance with this invention incorporated into one form of liquid dispensing apparatus supplied from an infusion drip set.

Liquid to be infused into a patient can pass through on outlet pipe 1 from a storage bottle 2 and be formed at the lower end of the pipe in an airtight drip forming chamber 3 into droplets. From this chamber, liquid can be pumped by a positive displacement pump A, which is preferably a peristaltic pump, via a pipe 4 of polyvinylchloride for example, a connector 5, a tube 6 and a connector 7, into a reservoir 8 provided by a closed ended limb tube of a Ttube 9 whose arm tubes are respectively connected to the connector 7 and a further connector 10.

The limb tube is closed-ended to prevent entry of any contaminants into the reservoir. The parts 1 to 5 constitute a standard drip set 11. It will of course be appreciated that any other suitable form of storage reservoir and administration set could be used in place of the drip set 11 which is illustrated merely by way of example. The reservoir 8 extends through a block 12 including liquid level sensing detectors, D, E, F, which can be optical detectors operating in the infrared region. The purpose of these detectors will be described below. Liquid can be pumped from the reservoir 8 by a positive displacement pump B, which is preferably a peristaltic pump, via a tube 13, a connector 14 and a tube 15, again of polyvinylchloride for example, to an infusion needle (not shown) inserted into the patient.

The tubes 6 and 13 are each made of material which can be resiliently deformed to close at least partially the passage within the tube. A particularly suitable material is silicone rubber tube. Where the pumps A, B are roller pumps, the tubes 6 and 13 are placed around the rollers so that when each pump rotor rotates, the rollers exert a pumping action on liquid in the tube. Alternatively, the pumps could be three- (or more) finger peristaltic pumps. The pumps can operate at the same or different pressures.

In use, the liquid system is primed and then the tubes 6, 13 placed around the pump rollers. With pump B at rest, pump A is started to pump liquid into the reservoir 8, compressing air in the reservoir above the liquid, until the liquid rises to the level of detector D. Pump A then stops and pump B starts to dispense liquid from the reservoir into the patient via the tube 15. When the liquid level has fallen to the level of detector E, pump B stops and pump A starts again. This operating cycle is then repeated continuously.

By way of example, for a dispensed flow rate of 60 ml./hr and if the difference in level between the detectors D and E represents a dispensed volume of 1 ml, the cycle operating time is 1 minute. Clearly, it would be desirable for the volume of liquid dispensed per unit time to be adjustable over a large range and the pumps may be unable to provide suf ficientvariation. For this purpose the detector F is used. As an example, for a flow operating range of 1 ml to 240 ml per hour, the time interval occupied by each cycle would range from 1 5-seconds to 1 hour.

The detector F could be provided at a level above detector E to represent a dispensed volume of 0.1 ml. Then, infusion rates of 10 mis and below could be infused at 0.1 volumes per time interval. Then, the longest time interval would be 6 minutes instead of 1 hour. A selector (not shown) is used to select detector E or F, depending on the range required.

It is pointed out in particular that the tube assem bly consisting of the parts 5, 6, 7, 9, 10, 13, 14 and 15 is intended to form a disposable unit which is replaced when required, for example each time a fresh bottle of liquid is to be infused. It will be appreciated that the tube assembly is extremely cheap to produce and this is most advantageous bearing in mind the number of bottles which any given piece of infusion equipment will be required to dispense over any particular period oftime.

Expediently, the drive to the two pumps can be provided by a single electric motor operatively coupled respectively by two one-way clutches and two gear boxes to the pumps. When the motor drives in one direction, one of the clutches slips while the other one transmits drive and vice versa for the opposite direction of motor drive.

A controller 16 can be used to control the entire operating sequence and can be arranged to operate an alarm 17 when certain monitored parameters indicate malfunction. For example, using a detector G, the controller can monitor the level in drip set for the level falling below a minimum value, and/or monitor the time for which detector D is uncovered to determine whether the normal cycle operating time is exceeded and/or monitor the current drawn by the motor per operating cycle and thereby detect the occurrence of the motor-on time exceeding a limit set to just above the time occupied by one complete operating cycle. Other safety factors include limiting the delivery pressure of each pump.

In a development, the controller can serve to operate the selector for the detectors D, F automatically, in dependence upon the magnitude of a desired delivery rate set in the controller.

In a modification, either or both pumps could be replaced by any suitable means, e.g. a flow control valve, but naturally this would only be possible where the quid supply pressure to the tube 6 is adequate. Although it is highly desirable to use peristaltic pumps, other forms of pump could alternatively be employed but then the cost of the disposable unit would be increased.

In addition to the cheapness of the disposable tube assembly, the described dispensing apparatus is especially advantageous in that when using peristaltic pump B, the infusion pressure into the patient can very easily be set to just above the minimum pressure required for infusion merely by adjusting the tube tension over the pump rollers. Furthermore, any air admitted to the reservoir 8 will rise to the air space but no air can possibly be pumped from the air space into the patient because the detector E switches off the pump B as soon as the liquid in the reservoir has fallen to the level of that detector.

It should also be noted that if too much air enters the air space, the pump A will be unable to raise the liquid level to that of the detector monitoring the upper level. This in turn prevents pump B from operating. The closed end of the limb tube of the T-tube can be provided with a filter serving as a pressure relief valve to relieve excess pressure from the air space while preventing entry of any contaminants into the reservoir. In one form, the filter can incorporate sintered metal as the filter material.

Claims (8)

1. A tube assembly for use in infusion apparatus, comprising a T-tube of which the limb constitutes a reservoir for liquid and is closed at its free end to provide, in use, an air space above liquid in the reservoir, a first tube connected to one arm tube of the T-tube for conveying to the reservoir liquid to be infused, and a second tube connected at one end to the other arm of the T-tube and at the other end to a third tube for conveying liquid from the reservoir to an infusion needle, the first and second tubes each being made of material which can be resiliently deformed to close at least partially the passage within the tube.

2. A tube assembly according to claim 1, wherein the first and second tubes are made of silicone rubber tubing.

3. A tube assembly according to claim 1 or 2, wherein the limb tube of the T-tube is closed at its free end with a filter serving as pressure relief means to relieve excess pressure in the air space while preventing entry of any contaminants into the reservoir.

4. A tube assembly according to claim 3, wherein the filter incorporates sintered metal as the filter material.

5. Apparatus for dispensing a predetermined quantity of liquid, comprising a T-tube of which the limb tube constitutes a reservoir for liquid and is closed at its free end to provide, in use, an air space above liquid in the reservoir, a first tube connected to one arm tube of the T-tube for conveying to the reservoir liquid to be infused and made of resiliently deformable material to enable the passage within the tube to be closed at least partially, a second tube made of a material having the same deformation property as the first tube and connected at one end to the other arm of the T-tube and at the other end to a third tube, leading to an infusion needle, for conveying liquid from the reservoir to the needle, a first peristaltic pump operative to exert a pumping action on said first tube, a first level detector arranged to render said first peristaltic pump inoperative once liquid has been pumped into the reservoir to a predetermined datum level, a second peristaltic pump operative to exert a pumping action on said second tube, a second level detector arranged to render the second pump inoperative when liquid in the reservoir has fallen from said datum level to a predetermined lower level, and a controller arranged to control operation of the two pumps cyclically so as to deliver a predetermined quantity of liquid from the infusion needle at regular intervals.

6. Apparatus according to claim 5, wherein the controller is responsive to the value of at least one parameter dependent upon the operation of the apparatus, and is arranged to provide an output indication in the event of the value of the parameter, or any one of the parameters, changing by a significant amount indicative of malfunction of the apparatus.

7. Apparatus according to claim 5 or 6, wherein a drip set, including a drip forming chamber, is connected to the inlet of said first tube, and the controller is responsive to the output value of a level detector, positioned to monitor the liquid level in said drip forming chamber, so asto provide an output indication in the event of the monitored level falling below a predetermined minimum level.

8. A tube assembly as claimed in claim 1, and substantially as hereinbefore described with reference to and as illustrated in the accompanying drawing.