GB202007577D0 - Hdr enhancers - Google Patents
Hdr enhancersInfo
- Publication number
- GB202007577D0 GB202007577D0 GBGB2007577.6A GB202007577A GB202007577D0 GB 202007577 D0 GB202007577 D0 GB 202007577D0 GB 202007577 A GB202007577 A GB 202007577A GB 202007577 D0 GB202007577 D0 GB 202007577D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- hdr
- enhancers
- hdr enhancers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB2007577.6A GB202007577D0 (en) | 2020-05-21 | 2020-05-21 | Hdr enhancers |
PCT/GB2021/051215 WO2021234388A1 (en) | 2020-05-21 | 2021-05-20 | Hdr enhancers |
EP21728104.7A EP4153739A1 (en) | 2020-05-21 | 2021-05-20 | Hdr enhancers |
US17/999,307 US20230183750A1 (en) | 2020-05-21 | 2021-05-20 | Hdr enhancers |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB2007577.6A GB202007577D0 (en) | 2020-05-21 | 2020-05-21 | Hdr enhancers |
Publications (1)
Publication Number | Publication Date |
---|---|
GB202007577D0 true GB202007577D0 (en) | 2020-07-08 |
Family
ID=71170676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB2007577.6A Ceased GB202007577D0 (en) | 2020-05-21 | 2020-05-21 | Hdr enhancers |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB202007577D0 (en) |
Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090203140A1 (en) | 2007-09-27 | 2009-08-13 | Sangamo Biosciences, Inc. | Genomic editing in zebrafish using zinc finger nucleases |
US20100218264A1 (en) | 2008-12-04 | 2010-08-26 | Sangamo Biosciences, Inc. | Genome editing in rats using zinc-finger nucleases |
US20100291048A1 (en) | 2009-03-20 | 2010-11-18 | Sangamo Biosciences, Inc. | Modification of CXCR4 using engineered zinc finger proteins |
US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
US20110041195A1 (en) | 2009-08-11 | 2011-02-17 | Sangamo Biosciences, Inc. | Organisms homozygous for targeted modification |
US7919313B2 (en) | 2007-07-12 | 2011-04-05 | Sangamo Biosciences, Inc. | Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression |
US7951925B2 (en) | 2006-05-25 | 2011-05-31 | Sangamo Biosciences, Inc. | Methods and compositions for gene inactivation |
US8110379B2 (en) | 2007-04-26 | 2012-02-07 | Sangamo Biosciences, Inc. | Targeted integration into the PPP1R12C locus |
US8153399B2 (en) | 2008-10-29 | 2012-04-10 | Sangamo Biosciences, Inc. | Methods and compositions for inactivating glutamine synthetase gene expression |
US8399218B2 (en) | 2007-09-27 | 2013-03-19 | Dow Agrosciences, Llc | Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes |
US8409861B2 (en) | 2003-08-08 | 2013-04-02 | Sangamo Biosciences, Inc. | Targeted deletion of cellular DNA sequences |
US8586526B2 (en) | 2010-05-17 | 2013-11-19 | Sangamo Biosciences, Inc. | DNA-binding proteins and uses thereof |
US8597912B2 (en) | 2008-06-10 | 2013-12-03 | Sangamo Biosciences, Inc. | Methods and compositions for generation of Bax-and Bak-deficient cell lines |
-
2020
- 2020-05-21 GB GBGB2007577.6A patent/GB202007577D0/en not_active Ceased
Patent Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
US8409861B2 (en) | 2003-08-08 | 2013-04-02 | Sangamo Biosciences, Inc. | Targeted deletion of cellular DNA sequences |
US7951925B2 (en) | 2006-05-25 | 2011-05-31 | Sangamo Biosciences, Inc. | Methods and compositions for gene inactivation |
US8110379B2 (en) | 2007-04-26 | 2012-02-07 | Sangamo Biosciences, Inc. | Targeted integration into the PPP1R12C locus |
US7919313B2 (en) | 2007-07-12 | 2011-04-05 | Sangamo Biosciences, Inc. | Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression |
US20090203140A1 (en) | 2007-09-27 | 2009-08-13 | Sangamo Biosciences, Inc. | Genomic editing in zebrafish using zinc finger nucleases |
US8399218B2 (en) | 2007-09-27 | 2013-03-19 | Dow Agrosciences, Llc | Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes |
US8597912B2 (en) | 2008-06-10 | 2013-12-03 | Sangamo Biosciences, Inc. | Methods and compositions for generation of Bax-and Bak-deficient cell lines |
US8153399B2 (en) | 2008-10-29 | 2012-04-10 | Sangamo Biosciences, Inc. | Methods and compositions for inactivating glutamine synthetase gene expression |
US20100218264A1 (en) | 2008-12-04 | 2010-08-26 | Sangamo Biosciences, Inc. | Genome editing in rats using zinc-finger nucleases |
US20100291048A1 (en) | 2009-03-20 | 2010-11-18 | Sangamo Biosciences, Inc. | Modification of CXCR4 using engineered zinc finger proteins |
US20110041195A1 (en) | 2009-08-11 | 2011-02-17 | Sangamo Biosciences, Inc. | Organisms homozygous for targeted modification |
US8586526B2 (en) | 2010-05-17 | 2013-11-19 | Sangamo Biosciences, Inc. | DNA-binding proteins and uses thereof |
Non-Patent Citations (14)
Title |
---|
BRINER, A. E. ET AL.: "Guide RNA functional modules direct cas9 activity and orthogonality", MOLECULAR CELL, vol. 56, no. 2, 2014, pages 333 - 339, XP055376599, DOI: 10.1016/j.molcel.2014.09.019 |
BUNTING ET AL.: "53BP1 Inhibits Homologous Recombination in Brca1-deficient Cells by Blocking Resection of DNA Breaks", CELL, vol. 141, no. 2, 2010, pages 243 - 54, XP055430025, DOI: 10.1016/j.cell.2010.03.012 |
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 1627607-88-8 |
ESCRIBANO-DIAZ ET AL.: "DNA repair pathway choice-a PTIP of the hat to 53BP1", EMBO REPORTS, vol. 14, no. 8, 2013, pages 665 - 666 |
FRADET-TURCOTTE ET AL.: "53BP1 Is a Reader of the DNA-damage-induced H2A Lys 15 Ubiquitin Mark", NATURE, vol. 499, no. 7456, 2013, pages 50 - 4, XP055404671, DOI: 10.1038/nature12318 |
GREEN, MRSAMBROOK, J.: "Molecular Cloning: A Laboratory Manual", 2014 |
JINEK, M. ET AL.: "A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity", SCIENCE, vol. 337, 2012, pages 816 - 821, XP055549487, DOI: 10.1126/science.1225829 |
JINEK, M. ET AL.: "A Programmable dual-RNA-guided DNA Endonuclease in Adaptive Bacterial Immunity", SCIENCE, vol. 337, no. 6096, 2012, pages 816 - 21, XP055549487, DOI: 10.1126/science.1225829 |
PROC. NATL. ACAD. SCI. USA., vol. 92, no. 16, 1 August 1995 (1995-08-01), pages 7297 - 301 |
SARTORI ET AL.: "Human CtIP Promotes DNA End Resection", NATURE, vol. 450, no. 7169, 2007, pages 509 - 14 |
SYMINGTON ET AL.: "Double-strand Break End Resection and Repair Pathway Choice", ANNU REV GENET, vol. 45, 2011, pages 247 - 71 |
SYMINGTON ET AL.: "Mechanism and Regulation of DNA End Resection in Eukaryotes", CRIT REV BIOCHEM MOL BIOL., vol. 51, no. 3, 2016, pages 195 - 212 |
ZAKHARYEVICH ET AL.: "Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand-break resection and resolution of double-Holliday Junctions", MOL CELL, vol. 40, no. 6, 2010, pages 1001 - 1015 |
ZIMMERMANN ET AL.: "53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection", SCIENCE, vol. 339, no. 6120, 2013, pages 700 - 4, XP055446395, DOI: 10.1126/science.1231573 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |