GB202007577D0 - Hdr enhancers - Google Patents

Hdr enhancers

Info

Publication number
GB202007577D0
GB202007577D0 GBGB2007577.6A GB202007577A GB202007577D0 GB 202007577 D0 GB202007577 D0 GB 202007577D0 GB 202007577 A GB202007577 A GB 202007577A GB 202007577 D0 GB202007577 D0 GB 202007577D0
Authority
GB
United Kingdom
Prior art keywords
hdr
enhancers
hdr enhancers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB2007577.6A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Oxford Genetics Ltd
Original Assignee
Oxford University Innovation Ltd
Oxford Genetics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd, Oxford Genetics Ltd filed Critical Oxford University Innovation Ltd
Priority to GBGB2007577.6A priority Critical patent/GB202007577D0/en
Publication of GB202007577D0 publication Critical patent/GB202007577D0/en
Priority to PCT/GB2021/051215 priority patent/WO2021234388A1/en
Priority to EP21728104.7A priority patent/EP4153739A1/en
Priority to US17/999,307 priority patent/US20230183750A1/en
Ceased legal-status Critical Current

Links

GBGB2007577.6A 2020-05-21 2020-05-21 Hdr enhancers Ceased GB202007577D0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GBGB2007577.6A GB202007577D0 (en) 2020-05-21 2020-05-21 Hdr enhancers
PCT/GB2021/051215 WO2021234388A1 (en) 2020-05-21 2021-05-20 Hdr enhancers
EP21728104.7A EP4153739A1 (en) 2020-05-21 2021-05-20 Hdr enhancers
US17/999,307 US20230183750A1 (en) 2020-05-21 2021-05-20 Hdr enhancers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2007577.6A GB202007577D0 (en) 2020-05-21 2020-05-21 Hdr enhancers

Publications (1)

Publication Number Publication Date
GB202007577D0 true GB202007577D0 (en) 2020-07-08

Family

ID=71170676

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB2007577.6A Ceased GB202007577D0 (en) 2020-05-21 2020-05-21 Hdr enhancers

Country Status (1)

Country Link
GB (1) GB202007577D0 (en)

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090203140A1 (en) 2007-09-27 2009-08-13 Sangamo Biosciences, Inc. Genomic editing in zebrafish using zinc finger nucleases
US20100218264A1 (en) 2008-12-04 2010-08-26 Sangamo Biosciences, Inc. Genome editing in rats using zinc-finger nucleases
US20100291048A1 (en) 2009-03-20 2010-11-18 Sangamo Biosciences, Inc. Modification of CXCR4 using engineered zinc finger proteins
US7888121B2 (en) 2003-08-08 2011-02-15 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
US20110041195A1 (en) 2009-08-11 2011-02-17 Sangamo Biosciences, Inc. Organisms homozygous for targeted modification
US7919313B2 (en) 2007-07-12 2011-04-05 Sangamo Biosciences, Inc. Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
US7951925B2 (en) 2006-05-25 2011-05-31 Sangamo Biosciences, Inc. Methods and compositions for gene inactivation
US8110379B2 (en) 2007-04-26 2012-02-07 Sangamo Biosciences, Inc. Targeted integration into the PPP1R12C locus
US8153399B2 (en) 2008-10-29 2012-04-10 Sangamo Biosciences, Inc. Methods and compositions for inactivating glutamine synthetase gene expression
US8399218B2 (en) 2007-09-27 2013-03-19 Dow Agrosciences, Llc Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
US8409861B2 (en) 2003-08-08 2013-04-02 Sangamo Biosciences, Inc. Targeted deletion of cellular DNA sequences
US8586526B2 (en) 2010-05-17 2013-11-19 Sangamo Biosciences, Inc. DNA-binding proteins and uses thereof
US8597912B2 (en) 2008-06-10 2013-12-03 Sangamo Biosciences, Inc. Methods and compositions for generation of Bax-and Bak-deficient cell lines

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7888121B2 (en) 2003-08-08 2011-02-15 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
US8409861B2 (en) 2003-08-08 2013-04-02 Sangamo Biosciences, Inc. Targeted deletion of cellular DNA sequences
US7951925B2 (en) 2006-05-25 2011-05-31 Sangamo Biosciences, Inc. Methods and compositions for gene inactivation
US8110379B2 (en) 2007-04-26 2012-02-07 Sangamo Biosciences, Inc. Targeted integration into the PPP1R12C locus
US7919313B2 (en) 2007-07-12 2011-04-05 Sangamo Biosciences, Inc. Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
US20090203140A1 (en) 2007-09-27 2009-08-13 Sangamo Biosciences, Inc. Genomic editing in zebrafish using zinc finger nucleases
US8399218B2 (en) 2007-09-27 2013-03-19 Dow Agrosciences, Llc Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
US8597912B2 (en) 2008-06-10 2013-12-03 Sangamo Biosciences, Inc. Methods and compositions for generation of Bax-and Bak-deficient cell lines
US8153399B2 (en) 2008-10-29 2012-04-10 Sangamo Biosciences, Inc. Methods and compositions for inactivating glutamine synthetase gene expression
US20100218264A1 (en) 2008-12-04 2010-08-26 Sangamo Biosciences, Inc. Genome editing in rats using zinc-finger nucleases
US20100291048A1 (en) 2009-03-20 2010-11-18 Sangamo Biosciences, Inc. Modification of CXCR4 using engineered zinc finger proteins
US20110041195A1 (en) 2009-08-11 2011-02-17 Sangamo Biosciences, Inc. Organisms homozygous for targeted modification
US8586526B2 (en) 2010-05-17 2013-11-19 Sangamo Biosciences, Inc. DNA-binding proteins and uses thereof

Non-Patent Citations (14)

* Cited by examiner, † Cited by third party
Title
BRINER, A. E. ET AL.: "Guide RNA functional modules direct cas9 activity and orthogonality", MOLECULAR CELL, vol. 56, no. 2, 2014, pages 333 - 339, XP055376599, DOI: 10.1016/j.molcel.2014.09.019
BUNTING ET AL.: "53BP1 Inhibits Homologous Recombination in Brca1-deficient Cells by Blocking Resection of DNA Breaks", CELL, vol. 141, no. 2, 2010, pages 243 - 54, XP055430025, DOI: 10.1016/j.cell.2010.03.012
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 1627607-88-8
ESCRIBANO-DIAZ ET AL.: "DNA repair pathway choice-a PTIP of the hat to 53BP1", EMBO REPORTS, vol. 14, no. 8, 2013, pages 665 - 666
FRADET-TURCOTTE ET AL.: "53BP1 Is a Reader of the DNA-damage-induced H2A Lys 15 Ubiquitin Mark", NATURE, vol. 499, no. 7456, 2013, pages 50 - 4, XP055404671, DOI: 10.1038/nature12318
GREEN, MRSAMBROOK, J.: "Molecular Cloning: A Laboratory Manual", 2014
JINEK, M. ET AL.: "A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity", SCIENCE, vol. 337, 2012, pages 816 - 821, XP055549487, DOI: 10.1126/science.1225829
JINEK, M. ET AL.: "A Programmable dual-RNA-guided DNA Endonuclease in Adaptive Bacterial Immunity", SCIENCE, vol. 337, no. 6096, 2012, pages 816 - 21, XP055549487, DOI: 10.1126/science.1225829
PROC. NATL. ACAD. SCI. USA., vol. 92, no. 16, 1 August 1995 (1995-08-01), pages 7297 - 301
SARTORI ET AL.: "Human CtIP Promotes DNA End Resection", NATURE, vol. 450, no. 7169, 2007, pages 509 - 14
SYMINGTON ET AL.: "Double-strand Break End Resection and Repair Pathway Choice", ANNU REV GENET, vol. 45, 2011, pages 247 - 71
SYMINGTON ET AL.: "Mechanism and Regulation of DNA End Resection in Eukaryotes", CRIT REV BIOCHEM MOL BIOL., vol. 51, no. 3, 2016, pages 195 - 212
ZAKHARYEVICH ET AL.: "Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand-break resection and resolution of double-Holliday Junctions", MOL CELL, vol. 40, no. 6, 2010, pages 1001 - 1015
ZIMMERMANN ET AL.: "53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection", SCIENCE, vol. 339, no. 6120, 2013, pages 700 - 4, XP055446395, DOI: 10.1126/science.1231573

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)