GB201315196D0 - Apparatus and method for determining the mechanical properties of cells - Google Patents
Apparatus and method for determining the mechanical properties of cellsInfo
- Publication number
- GB201315196D0 GB201315196D0 GB201315196A GB201315196A GB201315196D0 GB 201315196 D0 GB201315196 D0 GB 201315196D0 GB 201315196 A GB201315196 A GB 201315196A GB 201315196 A GB201315196 A GB 201315196A GB 201315196 D0 GB201315196 D0 GB 201315196D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- cells
- determining
- mechanical properties
- properties
- mechanical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1023—Microstructural devices for non-optical measurement
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/10—Segmentation; Edge detection
- G06T7/11—Region-based segmentation
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/40—Extraction of image or video features
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
- G06V20/693—Acquisition
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V40/00—Recognition of biometric, human-related or animal-related patterns in image or video data
- G06V40/10—Human or animal bodies, e.g. vehicle occupants or pedestrians; Body parts, e.g. hands
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Theoretical Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Multimedia (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Molecular Biology (AREA)
- Human Computer Interaction (AREA)
- Medical Informatics (AREA)
- Quality & Reliability (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Signal Processing (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB201315196A GB201315196D0 (en) | 2013-08-23 | 2013-08-23 | Apparatus and method for determining the mechanical properties of cells |
PCT/EP2014/063532 WO2015024690A1 (en) | 2013-08-23 | 2014-06-26 | Apparatus and method for determining the mechanical properties of cells |
US14/913,699 US10571387B2 (en) | 2013-08-23 | 2014-06-26 | Apparatus and method for determining the mechanical properties of cells |
EP14732901.5A EP3036520B1 (en) | 2013-08-23 | 2014-06-26 | Apparatus and method for determining the mechanical properties of cells |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB201315196A GB201315196D0 (en) | 2013-08-23 | 2013-08-23 | Apparatus and method for determining the mechanical properties of cells |
Publications (1)
Publication Number | Publication Date |
---|---|
GB201315196D0 true GB201315196D0 (en) | 2013-10-09 |
Family
ID=49355915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB201315196A Ceased GB201315196D0 (en) | 2013-08-23 | 2013-08-23 | Apparatus and method for determining the mechanical properties of cells |
Country Status (4)
Country | Link |
---|---|
US (1) | US10571387B2 (en) |
EP (1) | EP3036520B1 (en) |
GB (1) | GB201315196D0 (en) |
WO (1) | WO2015024690A1 (en) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2906928A4 (en) | 2012-10-15 | 2016-11-09 | Nanocellect Biomedical Inc | Systems, apparatus, and methods for sorting particles |
US20150338248A1 (en) * | 2013-01-11 | 2015-11-26 | Council Of Scientific & Industrial Research | An optical fiber-based force transducer for microscale samples |
EP2990742A1 (en) * | 2014-08-28 | 2016-03-02 | ABB Technology AG | Method and apparatus for solidifying a polar substance |
US10409704B1 (en) * | 2015-10-05 | 2019-09-10 | Quest Software Inc. | Systems and methods for resource utilization reporting and analysis |
GB2567788B (en) | 2016-11-06 | 2022-04-20 | Halliburton Energy Services Inc | Automated inversion workflow for defect detection tools |
DE102017201252A1 (en) | 2017-01-26 | 2018-07-26 | Universität Ulm | Method and device for the examination of cells |
DE102017008946A1 (en) * | 2017-09-23 | 2019-03-28 | Universität Greifswald | Method of deforming deformable bodies and devices therefor |
DE102017219565A1 (en) | 2017-11-03 | 2019-05-09 | Ernst-Moritz-Arndt-Universität Greifswald | Method for quality control of cellular blood products |
GB2575494A (en) * | 2018-07-12 | 2020-01-15 | Zellmechanik Dresden Gmbh | Method of obtaining an indicator of patient sepsis and apparatus for such a method |
CN109136081A (en) * | 2018-07-30 | 2019-01-04 | 上海大学 | Cancer cell separator and control system based on cells deformation amount and surface acoustic wave |
DE102018221232A1 (en) | 2018-12-07 | 2020-07-02 | Universität Greifswald | Diagnostic support method and apparatus therefor |
CN111474106A (en) * | 2019-01-23 | 2020-07-31 | 香港科技大学 | Method and system for determining mechanical properties of biological cells or biological cell-like particles |
EP3796212A1 (en) | 2019-09-23 | 2021-03-24 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Device for image-based cell classification, method therefor and use thereof |
JP7316912B2 (en) * | 2019-11-12 | 2023-07-28 | 株式会社日立製作所 | Cell sheet evaluation method |
CN111744565B (en) * | 2020-05-26 | 2022-03-08 | 东南大学 | Microfluidic device and system for multi-channel parallel detection of cell deformability |
CN112764596B (en) * | 2021-01-18 | 2023-04-21 | 四川中微芯成科技有限公司 | Capacitive touch anti-interference detection device, system and method |
CN113008766B (en) * | 2021-03-03 | 2022-08-23 | 北京理工大学 | Cancer cell dynamic behavior detection system based on microfluidic multi-extrusion |
CN113008765B (en) * | 2021-03-03 | 2022-08-23 | 北京理工大学 | Cancer cell dynamic behavior detection system adopting deformable micro-channel |
EP4083607A1 (en) | 2021-04-26 | 2022-11-02 | ETH Zurich | Method and microfluidic device for studying cell deformations |
CN113533171A (en) * | 2021-07-01 | 2021-10-22 | 芯峰科技(广州)有限公司 | Cell deformation detection method and system based on deep learning and microfluidic chip |
EP4122598B1 (en) | 2021-07-20 | 2024-04-10 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | A system for dissociation of solid biopsy and a method for inspection |
CN114199835B (en) * | 2021-11-05 | 2023-10-24 | 华南师范大学 | Detection method of circulating tumor cells and application thereof |
EP4209775A1 (en) | 2022-01-05 | 2023-07-12 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Method for determining a number of viscoelastic properties of a number of particles in a suspension, device for such a method and computer program or computer program product |
US20230241611A1 (en) * | 2022-01-31 | 2023-08-03 | Tdk Corporation | Devices and Methods for Sensing and Sorting Particles |
EP4242658A1 (en) | 2022-03-10 | 2023-09-13 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | A system and method for biomolecule detection |
CN114778422B (en) * | 2022-04-19 | 2023-09-08 | 北京理工大学 | Automatic cell sorting system and method based on micro-droplet control technology |
EP4296645A1 (en) * | 2022-06-24 | 2023-12-27 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Method and apparatus for determining rheological properties of deformable bodies |
FR3140171A1 (en) | 2022-09-23 | 2024-03-29 | Centre National De La Recherche Scientifique | DEVICE AND METHOD FOR THE CHARACTERIZATION OF CELLS SUBJECTED TO PHYSICAL STRAIN |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1815352C3 (en) | 1968-12-18 | 1975-03-20 | Wolfgang Prof. Dr. Dittrich | Automatic measuring and counting device for the particles of a dispersion |
FR2484077B1 (en) | 1980-06-06 | 1984-07-06 | Inst Nat Sante Rech Med | METHOD AND DEVICE FOR MEASURING THE DEFORMABILITY OF LIVING CELLS, ESPECIALLY RED BLOOD CELLS |
US5798827A (en) * | 1996-11-26 | 1998-08-25 | Coulter International Corp. | Apparatus and method for determination of individual red blood cell shape |
EP1059871B1 (en) | 1998-03-04 | 2005-07-13 | Guck Jochen | Optical stretcher |
JP3871456B2 (en) | 1998-12-10 | 2007-01-24 | シスメックス株式会社 | Particle image analyzer |
US7542131B2 (en) | 2003-06-23 | 2009-06-02 | Sewon Meditech, Inc. | Apparatus for measuring blood cell deformability |
US20070008528A1 (en) | 2005-07-07 | 2007-01-11 | Chi-Hung Lin | Device and method for simultaneous optical trapping, stretching, and real-time detection and measurement for morphological deformation of micro-particles |
EP2619545B1 (en) * | 2010-09-22 | 2019-01-30 | The Regents of The University of California | System for high throughput cell deformability measurements |
US9090865B2 (en) | 2010-10-29 | 2015-07-28 | The Regents Of The University Of California | Systems and methods for particle classification and sorting |
-
2013
- 2013-08-23 GB GB201315196A patent/GB201315196D0/en not_active Ceased
-
2014
- 2014-06-26 US US14/913,699 patent/US10571387B2/en active Active
- 2014-06-26 WO PCT/EP2014/063532 patent/WO2015024690A1/en active Application Filing
- 2014-06-26 EP EP14732901.5A patent/EP3036520B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
US10571387B2 (en) | 2020-02-25 |
US20160202172A1 (en) | 2016-07-14 |
WO2015024690A1 (en) | 2015-02-26 |
EP3036520B1 (en) | 2017-07-26 |
EP3036520A1 (en) | 2016-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |