GB201306569D0 - Tannin extract of sanguisorba officinalis L. and preparation method and use thereof - Google Patents
Tannin extract of sanguisorba officinalis L. and preparation method and use thereofInfo
- Publication number
- GB201306569D0 GB201306569D0 GBGB1306569.3A GB201306569A GB201306569D0 GB 201306569 D0 GB201306569 D0 GB 201306569D0 GB 201306569 A GB201306569 A GB 201306569A GB 201306569 D0 GB201306569 D0 GB 201306569D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- sanguisorba officinalis
- preparation
- tannin extract
- extract
- tannin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000018553 tannin Nutrition 0.000 title abstract 3
- 229920001864 tannin Polymers 0.000 title abstract 3
- 239000001648 tannin Substances 0.000 title abstract 3
- 244000173853 Sanguisorba officinalis Species 0.000 title abstract 2
- 235000008282 Sanguisorba officinalis Nutrition 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 210000001185 bone marrow Anatomy 0.000 abstract 2
- 229930190125 Sanguisorbin Natural products 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 abstract 1
- 238000001959 radiotherapy Methods 0.000 abstract 1
- 229930182490 saponin Natural products 0.000 abstract 1
- 150000007949 saponins Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
A tannin extract of Sanguisorba officinalis L. contains tannin in a range of 35%-100% (w/w), wherein the content of total saponin is less than 10% (w/w), and the content of sanguisorbin I is less than 5% (w/w). The extract can protect bone marrow hematopoietic stem cells, relieve the inhibition of mouse bone marrow DNA caused by drugs for radiation therapy and chemotherapy, as well as increase numbers of leucocytes.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010280772 | 2010-09-14 | ||
CN201110186932 | 2011-07-05 | ||
PCT/CN2011/079633 WO2012034519A1 (en) | 2010-09-14 | 2011-09-14 | Tannin extract of sanguisorba officinalis l. and preparation method and use thereof |
Publications (3)
Publication Number | Publication Date |
---|---|
GB201306569D0 true GB201306569D0 (en) | 2013-05-22 |
GB2497899A GB2497899A (en) | 2013-06-26 |
GB2497899B GB2497899B (en) | 2018-05-30 |
Family
ID=45831012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1306569.3A Active GB2497899B (en) | 2010-09-14 | 2011-09-14 | Sanguiin for use in the prevention or treatment of bone marrow inhibition |
Country Status (5)
Country | Link |
---|---|
CN (3) | CN103784434A (en) |
GB (1) | GB2497899B (en) |
MY (1) | MY173437A (en) |
SG (2) | SG10201505752QA (en) |
WO (1) | WO2012034519A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103223036A (en) * | 2013-04-16 | 2013-07-31 | 阚兆云 | Traditional Chinese medicinal composition |
CN104435220B (en) * | 2013-09-22 | 2018-01-05 | 成都百草和济科技有限公司 | Treat the combination medicine of bone marrow suppression |
CN104623015A (en) * | 2013-11-08 | 2015-05-20 | 成都百草和济科技有限公司 | New application of garden burnet root and India madder root composition |
GB201413228D0 (en) | 2014-07-25 | 2014-09-10 | Nugerontix Ltd | Polyphenol compositions |
CN105147804B (en) * | 2015-08-28 | 2019-04-09 | 四川英路维特医药科技有限公司 | A kind of radix sanguisorbae total saponin extract and its preparation method and application |
US10155069B2 (en) | 2016-09-09 | 2018-12-18 | King Abdulaziz University | Bone graft with a tannin-hydroxyapatite scaffold and stem cells for bone engineering |
CN112876523B (en) * | 2021-03-30 | 2023-07-25 | 江西海富生物工程有限公司 | Method for recovering tannic acid from fructus momordicae, sweet tea or stevia rebaudiana floc residues |
CN114577970B (en) * | 2022-02-18 | 2023-05-12 | 江西普正制药股份有限公司 | Method for establishing blood level tablet fingerprint and fingerprint thereof |
CN115232516B (en) * | 2022-06-27 | 2023-06-06 | 中南林业科技大学 | Anti-adhesion coating with camellia saponin as main component, preparation method thereof and application thereof in inhibiting bacillus cereus |
CN115998703A (en) * | 2022-12-14 | 2023-04-25 | 迪沙药业集团有限公司 | Sanguisorba composition and preparation method thereof |
CN116688012B (en) * | 2023-07-05 | 2024-06-04 | 浙江工业大学 | Buccal tablet for preventing influenza |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58103383A (en) * | 1981-12-12 | 1983-06-20 | Nippon Shinyaku Co Ltd | New tannin |
JPS58154571A (en) * | 1982-03-08 | 1983-09-14 | Nippon Shinyaku Co Ltd | Novel tannin |
CN1824631A (en) * | 2005-12-29 | 2006-08-30 | 谢君 | Molecular modification method of active fat soluble plant polyphenol kind substance |
JP2010070540A (en) * | 2008-08-22 | 2010-04-02 | Kao Corp | Dgat inhibitor |
-
2011
- 2011-09-14 CN CN201410032553.5A patent/CN103784434A/en active Pending
- 2011-09-14 MY MYPI2013000864A patent/MY173437A/en unknown
- 2011-09-14 WO PCT/CN2011/079633 patent/WO2012034519A1/en active Application Filing
- 2011-09-14 CN CN201410032898.0A patent/CN103948710A/en active Pending
- 2011-09-14 CN CN2011800389315A patent/CN103079560A/en active Pending
- 2011-09-14 SG SG10201505752QA patent/SG10201505752QA/en unknown
- 2011-09-14 GB GB1306569.3A patent/GB2497899B/en active Active
- 2011-09-14 SG SG2013018692A patent/SG188529A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2012034519A1 (en) | 2012-03-22 |
CN103948710A (en) | 2014-07-30 |
CN103784434A (en) | 2014-05-14 |
GB2497899B (en) | 2018-05-30 |
SG188529A1 (en) | 2013-04-30 |
GB2497899A (en) | 2013-06-26 |
MY173437A (en) | 2020-01-24 |
SG10201505752QA (en) | 2015-09-29 |
CN103079560A (en) | 2013-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) |
Free format text: REGISTERED BETWEEN 20200227 AND 20200304 |