GB2006752B - Imidazole derivatives and salts thereof their synthesis and intermediates and pharmaceutical formulations - Google Patents

Imidazole derivatives and salts thereof their synthesis and intermediates and pharmaceutical formulations

Info

Publication number
GB2006752B
GB2006752B GB7834106A GB7834106A GB2006752B GB 2006752 B GB2006752 B GB 2006752B GB 7834106 A GB7834106 A GB 7834106A GB 7834106 A GB7834106 A GB 7834106A GB 2006752 B GB2006752 B GB 2006752B
Authority
GB
United Kingdom
Prior art keywords
intermediates
synthesis
salts
pharmaceutical formulations
imidazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7834106A
Other versions
GB2006752A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to US05/936,406 priority Critical patent/US4284641A/en
Priority to JP10374878A priority patent/JPS5455568A/en
Priority to DE7878100754T priority patent/DE2862409D1/en
Priority to EP78100754A priority patent/EP0000951B1/en
Publication of GB2006752A publication Critical patent/GB2006752A/en
Application granted granted Critical
Publication of GB2006752B publication Critical patent/GB2006752B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB7834106A 1977-08-26 1978-08-22 Imidazole derivatives and salts thereof their synthesis and intermediates and pharmaceutical formulations Expired GB2006752B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US05/936,406 US4284641A (en) 1977-08-26 1978-08-24 Pharmaceutically active imidazole derivatives
JP10374878A JPS5455568A (en) 1977-08-26 1978-08-25 11substituted imidazoles and pharmaceutical composition
DE7878100754T DE2862409D1 (en) 1977-08-26 1978-08-25 Pharmaceutical formulations comprising 1-substituted imidazoles, 1-substituted imidazoles and 1-substituted imidazoles for use in the treatment or prophylaxis of thrombo-embolic disorders
EP78100754A EP0000951B1 (en) 1977-08-26 1978-08-25 Pharmaceutical formulations comprising 1-substituted imidazoles, 1-substituted imidazoles and 1-substituted imidazoles for use in the treatment or prophylaxis of thrombo-embolic disorders

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB3591377 1977-08-26
GB3591277 1977-08-26
GB398478 1978-02-01
GB398378 1978-02-01
GB7832526 1978-08-08
GB7832536 1978-08-08

Publications (2)

Publication Number Publication Date
GB2006752A GB2006752A (en) 1979-05-10
GB2006752B true GB2006752B (en) 1982-07-21

Family

ID=27546483

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7834106A Expired GB2006752B (en) 1977-08-26 1978-08-22 Imidazole derivatives and salts thereof their synthesis and intermediates and pharmaceutical formulations

Country Status (3)

Country Link
DK (1) DK375878A (en)
GB (1) GB2006752B (en)
IL (1) IL55439A (en)

Also Published As

Publication number Publication date
IL55439A0 (en) 1978-10-31
IL55439A (en) 1982-07-30
DK375878A (en) 1979-02-27
GB2006752A (en) 1979-05-10

Similar Documents

Publication Publication Date Title
GB2018136B (en) Imidazole derivatives and salts thereof their synthesis and intermediates and pharmaceutical formulations
DE2861237D1 (en) Imidazole derivatives their synthesis and their pharmaceutical formulations
EP0002259A3 (en) Hydantoin derivatives and salts thereof, their synthesis and intermediates, and pharmaceutical formulations
HK54382A (en) Novel substituted phenoxybenzyloxycarbonyl derivatives andtheir use as insecticides and acaricides
NZ188140A (en) Nitroimidazole derivatives and pharmaceutical compositions
ZA783869B (en) Novel substituted phenoxybenzyloxycarbonyl derivatives and their use as insecticides and acaricides
NZ187849A (en) Prostaglandin i derivatives and pharmaceutical compositions
EP0001647A3 (en) Imidazoline derivatives and salts thereof, their synthesis, and intermediates, and pesticidal formulations
NZ188976A (en) Prostacyclin derivatives and pharmaceutical compositions
GB2044259B (en) Imidazole derivatives and salts thereof synthesis and pharmaceutical formulations
DE2862107D1 (en) Glucosamine-peptide derivatives and their pharmaceutical compositions
EP0013315A3 (en) Eburnane derivatives, including intermediates, their synthesis and pharmaceutical compositions containing them
DE2861638D1 (en) Hydantoin derivatives and salts thereof, their synthesis and intermediates, and pharmaceutical formulations
GB2010813B (en) Imidazole derivatives and salts thereof their synthesis and intermediates and pharmaceutical formulations
DE2862371D1 (en) Imidazole derivatives and salts thereof and their synthesis
NZ193557A (en) 4-phenylchroman derivatives intermediates and pharmaceutical compositions
NZ188101A (en) N-substituted-2-aminobenzoic acid derivatives and pharmaceutical compositions
NZ186410A (en) Imidazole derivatives and pharmaceutical compositions
GB2008089B (en) Imidazole derivatives and salts thereof their synthesis and intermediates and pharmaceutical formulations
GB2006752B (en) Imidazole derivatives and salts thereof their synthesis and intermediates and pharmaceutical formulations
IL61826A0 (en) Pharmaceutical compositions containing pyranoquinolinone derivatives
IL55208A0 (en) Novel pharmaceutical compositions comprising certain imidazole derivatives
NZ192520A (en) Hydantoin derivatives pharmaceutical compositions
DE2862424D1 (en) Hydantoin derivatives, their synthesis, pharmaceutical formulations and intermediates in their preparation
NZ186735A (en) 9-flouroprednisolone derivatives and pharmaceutical compositions

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee