GB2001956A - 5,6,7-Trimethoxy naphthalene-(2)- carboxylic acid and hydronaphthalene-(2)- carboxylic acid derivatives - Google Patents

5,6,7-Trimethoxy naphthalene-(2)- carboxylic acid and hydronaphthalene-(2)- carboxylic acid derivatives

Info

Publication number
GB2001956A
GB2001956A GB7826797A GB7826797A GB2001956A GB 2001956 A GB2001956 A GB 2001956A GB 7826797 A GB7826797 A GB 7826797A GB 7826797 A GB7826797 A GB 7826797A GB 2001956 A GB2001956 A GB 2001956A
Authority
GB
United Kingdom
Prior art keywords
group
carboxylic acid
hydronaphthalene
contain
alkyl radicals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB7826797A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH filed Critical Degussa GmbH
Publication of GB2001956A publication Critical patent/GB2001956A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds corresponding to the general formula <IMAGE> in which the hydrogenated 6-ring may also contain one or two double bonds and in which R<1> is a hydroxy group, a C1-C6alkoxy group, a halogen atom, a C2-C6-alkanoyloxy group, an amino group, a C1-C6-alkylamino group or a dialkylamino group with alkyl radicals of 1 to 6 carbon atoms, the alkyl radicals of the dialkylamino group also being capable of forming with the nitrogen atom a saturated heterocyclic 5- to 7-membered ring which may also contain an oxygen atom or another nitrogen atom, and the salts of these compounds show lipid-reducing properties and in particular produce a distinct reduction in the cholesterol level of hypercholesterolaemic mice. Some of the compounds show psychopharmacological activity and some are vasodilators.
GB7826797A 1977-06-13 1978-06-13 5,6,7-Trimethoxy naphthalene-(2)- carboxylic acid and hydronaphthalene-(2)- carboxylic acid derivatives Withdrawn GB2001956A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2453577 1977-06-13

Publications (1)

Publication Number Publication Date
GB2001956A true GB2001956A (en) 1979-02-14

Family

ID=10213176

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7826797A Withdrawn GB2001956A (en) 1977-06-13 1978-06-13 5,6,7-Trimethoxy naphthalene-(2)- carboxylic acid and hydronaphthalene-(2)- carboxylic acid derivatives

Country Status (4)

Country Link
BE (1) BE868023A (en)
DE (1) DE2824409A1 (en)
FR (1) FR2405236A1 (en)
GB (1) GB2001956A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705782A (en) * 1985-04-02 1987-11-10 Akzo N.V. Indene and naphthalene derivatives
US7115767B2 (en) * 2003-07-18 2006-10-03 Abbott Laboratories Tetraline derivatives as ghrelin receptor modulators

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705782A (en) * 1985-04-02 1987-11-10 Akzo N.V. Indene and naphthalene derivatives
US7115767B2 (en) * 2003-07-18 2006-10-03 Abbott Laboratories Tetraline derivatives as ghrelin receptor modulators

Also Published As

Publication number Publication date
BE868023A (en) 1978-12-11
DE2824409A1 (en) 1978-12-21
FR2405236A1 (en) 1979-05-04

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)