GB1539053A - Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins - Google Patents

Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins

Info

Publication number
GB1539053A
GB1539053A GB25845/76A GB2584576A GB1539053A GB 1539053 A GB1539053 A GB 1539053A GB 25845/76 A GB25845/76 A GB 25845/76A GB 2584576 A GB2584576 A GB 2584576A GB 1539053 A GB1539053 A GB 1539053A
Authority
GB
United Kingdom
Prior art keywords
oxoimidazolidinyl
carbonylamino
alpha
preparation
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB25845/76A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB1539053A publication Critical patent/GB1539053A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

beta -Lactam antibiotics of the formula <IMAGE> in which the substituents are defined in Claim 1, are prepared. These compounds are obtained by reacting corresponding cephem compounds which have the ester grouping CH2OCOCH3 in position 3 with a compound providing the radical T. The resulting compounds can be used as antibacterial agents.
GB25845/76A 1975-06-24 1976-06-22 Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins Expired GB1539053A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752528077 DE2528077A1 (en) 1975-06-24 1975-06-24 BETA-LACTAMANTIBIOTICS, THE METHOD OF MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT

Publications (1)

Publication Number Publication Date
GB1539053A true GB1539053A (en) 1979-01-24

Family

ID=5949818

Family Applications (1)

Application Number Title Priority Date Filing Date
GB25845/76A Expired GB1539053A (en) 1975-06-24 1976-06-22 Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins

Country Status (17)

Country Link
JP (1) JPS523094A (en)
AT (1) AT348118B (en)
AU (1) AU498095B2 (en)
BE (1) BE843343A (en)
CH (1) CH628056A5 (en)
DD (1) DD132344A5 (en)
DE (1) DE2528077A1 (en)
DK (1) DK281176A (en)
ES (1) ES449142A1 (en)
FI (1) FI761806A (en)
FR (1) FR2317302A1 (en)
GB (1) GB1539053A (en)
GR (1) GR60559B (en)
IL (1) IL49848A0 (en)
LU (1) LU75216A1 (en)
NL (1) NL7606788A (en)
SE (1) SE7607217L (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5331690A (en) * 1976-09-01 1978-03-25 Shionogi & Co Ltd Oxadithiacephalosporins
JPS61246187A (en) * 1985-09-05 1986-11-01 Shionogi & Co Ltd 1-oxadethiacepham compound
JPH02117677A (en) * 1989-09-22 1990-05-02 Shionogi & Co Ltd 1-oxadithiacepham compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2233067A1 (en) * 1973-06-12 1975-01-10 Beecham Group Ltd N-(thio)acyl carbamoyl-glycylamino-cephalosporin ic acids - as antibiotics esp. active against pseudomonas and gram neg. organisms producing cephalosporinase
DE2407715C2 (en) * 1974-02-18 1982-12-02 Bayer Ag, 5090 Leverkusen Cephalosporins, processes for their production, as well as pharmaceuticals

Also Published As

Publication number Publication date
ES449142A1 (en) 1977-07-16
FR2317302B1 (en) 1980-07-11
BE843343A (en) 1976-12-24
FR2317302A1 (en) 1977-02-04
GR60559B (en) 1978-06-22
AU1522276A (en) 1978-01-05
AT348118B (en) 1979-01-25
DE2528077A1 (en) 1977-01-20
FI761806A (en) 1976-12-25
NL7606788A (en) 1976-12-28
LU75216A1 (en) 1977-03-15
ATA461376A (en) 1978-06-15
DD132344A5 (en) 1978-09-20
JPS523094A (en) 1977-01-11
DK281176A (en) 1976-12-25
SE7607217L (en) 1976-12-25
IL49848A0 (en) 1976-08-31
AU498095B2 (en) 1979-02-08
CH628056A5 (en) 1982-02-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee