GB1481808A - Cepham derivatives and preparation thereof - Google Patents
Cepham derivatives and preparation thereofInfo
- Publication number
- GB1481808A GB1481808A GB22871/76A GB2287176A GB1481808A GB 1481808 A GB1481808 A GB 1481808A GB 22871/76 A GB22871/76 A GB 22871/76A GB 2287176 A GB2287176 A GB 2287176A GB 1481808 A GB1481808 A GB 1481808A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenyl
- preparation
- alkanoyloxy
- tetrazolyl
- benzyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
1481808 Cephem derivatives PFIZER Inc 14 Oct 1974 [17 Oct 1973] 22871/76 Divided out of 1481807 Heading C2C The invention comprises compounds of the formula and salts thereof, wherein T is a tetrazolyl precursor -CONHR 2 wherein R is H, 2,2,2-trichloro- or tribromoethoxycarbonyl, benzyloxycarbonyl or wherein R 3 , R 4 and R 5 are each selected from H, Cl, Br, F, CH 3 , CH 3 O and phenyl; A is H, CH 3 COO, 1 - methyl - tetrazolyl - 5 - thio or 2- methyl - 1,3,4 - thiadiazolyl - 5 - thio; and R 2 is selected from groups of the formulµ and wherein R 6 is (C 1 -C 3 )alkyl or phenyl, R 7 is OH, CH 3 O, (C 2 -C 4 )alkanoyloxy or benzyloxy, R 8 is H, OH, F, Cl, Br, I, CH 3 , CH 3 0, (C 2 -C 4 )- alkanoyloxy, phenyl or benzyloxy, R 9 and R 10 are each selected from H and CH 3 , and X is 0 or S. They may be obtained by reacting the corresponding free carboxylic compound with an appropriate amine, R 2 NH 2 . The products are intermediates useful in the preparation of antibacterial agents.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40709773A | 1973-10-17 | 1973-10-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1481808A true GB1481808A (en) | 1977-08-03 |
Family
ID=23610572
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB22873/76A Expired GB1481810A (en) | 1973-10-17 | 1974-10-14 | Cepham derivatives and preparation thereof |
| GB22872/76A Expired GB1481809A (en) | 1973-10-17 | 1974-10-14 | Cepham derivatives and preparation thereof |
| GB22871/76A Expired GB1481808A (en) | 1973-10-17 | 1974-10-14 | Cepham derivatives and preparation thereof |
| GB44350/74A Expired GB1481807A (en) | 1973-10-17 | 1974-10-14 | Cepham-derivatives and preparation thereof |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB22873/76A Expired GB1481810A (en) | 1973-10-17 | 1974-10-14 | Cepham derivatives and preparation thereof |
| GB22872/76A Expired GB1481809A (en) | 1973-10-17 | 1974-10-14 | Cepham derivatives and preparation thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB44350/74A Expired GB1481807A (en) | 1973-10-17 | 1974-10-14 | Cepham-derivatives and preparation thereof |
Country Status (22)
| Country | Link |
|---|---|
| JP (3) | JPS50121293A (en) |
| AR (2) | AR209283A1 (en) |
| BE (1) | BE821164A (en) |
| CA (1) | CA1064019A (en) |
| DD (1) | DD114266A5 (en) |
| DE (1) | DE2449834A1 (en) |
| DK (1) | DK542174A (en) |
| ES (4) | ES431069A1 (en) |
| FR (1) | FR2257298B1 (en) |
| GB (4) | GB1481810A (en) |
| IE (1) | IE40745B1 (en) |
| IL (1) | IL45849A0 (en) |
| LU (1) | LU71128A1 (en) |
| MW (2) | MW4074A1 (en) |
| NL (1) | NL7413643A (en) |
| NO (1) | NO743667L (en) |
| OA (1) | OA04935A (en) |
| PL (1) | PL95747B1 (en) |
| SE (2) | SE429342B (en) |
| SU (1) | SU974936A3 (en) |
| ZA (1) | ZA746544B (en) |
| ZM (1) | ZM16174A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140039202A (en) * | 2011-04-28 | 2014-04-01 | 시오노기세야쿠 가부시키가이샤 | Novel cephem compound having catechol or pseudo-catechol structure |
| JPWO2013002215A1 (en) * | 2011-06-27 | 2015-02-23 | 塩野義製薬株式会社 | Cephem compound having pyridinium group |
-
1974
- 1974-10-07 SE SE7412602A patent/SE429342B/en unknown
- 1974-10-11 NO NO743667A patent/NO743667L/no unknown
- 1974-10-14 GB GB22873/76A patent/GB1481810A/en not_active Expired
- 1974-10-14 GB GB22872/76A patent/GB1481809A/en not_active Expired
- 1974-10-14 GB GB22871/76A patent/GB1481808A/en not_active Expired
- 1974-10-14 GB GB44350/74A patent/GB1481807A/en not_active Expired
- 1974-10-14 IL IL45849A patent/IL45849A0/en unknown
- 1974-10-14 IE IE2113/74A patent/IE40745B1/en unknown
- 1974-10-15 MW MW40/74A patent/MW4074A1/en unknown
- 1974-10-15 MW MW41/74A patent/MW4174A1/en unknown
- 1974-10-15 ZA ZA00746544A patent/ZA746544B/en unknown
- 1974-10-16 AR AR256116A patent/AR209283A1/en active
- 1974-10-16 DK DK542174A patent/DK542174A/da not_active Application Discontinuation
- 1974-10-16 DD DD181737A patent/DD114266A5/xx unknown
- 1974-10-16 ES ES431069A patent/ES431069A1/en not_active Expired
- 1974-10-16 DE DE19742449834 patent/DE2449834A1/en not_active Ceased
- 1974-10-16 CA CA211,504A patent/CA1064019A/en not_active Expired
- 1974-10-17 PL PL1974174893A patent/PL95747B1/en unknown
- 1974-10-17 LU LU71128A patent/LU71128A1/xx unknown
- 1974-10-17 NL NL7413643A patent/NL7413643A/en not_active Application Discontinuation
- 1974-10-17 JP JP49118743A patent/JPS50121293A/ja active Pending
- 1974-10-17 FR FR7435015A patent/FR2257298B1/fr not_active Expired
- 1974-10-17 BE BE1006235A patent/BE821164A/en unknown
- 1974-10-18 OA OA55326A patent/OA04935A/en unknown
- 1974-11-04 ZM ZM161/74A patent/ZM16174A1/en unknown
-
1975
- 1975-08-18 AR AR260031A patent/AR213726A1/en active
-
1976
- 1976-08-02 ES ES450399A patent/ES450399A1/en not_active Expired
- 1976-08-02 ES ES450397A patent/ES450397A1/en not_active Expired
- 1976-08-02 ES ES450398A patent/ES450398A1/en not_active Expired
-
1977
- 1977-09-23 SE SE7710697A patent/SE7710697L/en not_active Application Discontinuation
-
1978
- 1978-06-28 SU SU782377452A patent/SU974936A3/en active
-
1982
- 1982-01-20 JP JP57007361A patent/JPS5822480B2/en not_active Expired
-
1983
- 1983-01-17 JP JP58005766A patent/JPS58131988A/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8104233A1 (en) | Quinoline carboxylic acid derivatives | |
| ES8101596A1 (en) | Antibacterial beta-lactams, pharmaceuticals thereof and methods of using them | |
| DK0416410T3 (en) | Piperaziniocephalosporins | |
| GB1428793A (en) | Cephalosporins | |
| IE40511B1 (en) | N-(1-(-phenylalkyl)-piperidyl-j)-(-(-pyridyl)-carbonic acid amides | |
| GB1344976A (en) | Aminoalkanol compounds and methods for their production | |
| GB1262965A (en) | Butyrophenones | |
| GB1456627A (en) | Pyridobenzodiazepinones | |
| GB1481808A (en) | Cepham derivatives and preparation thereof | |
| GB1435475A (en) | Beta-lactam antibiotic compounds their production and their medicinal use | |
| GB1381320A (en) | Benzoxazole derivatives | |
| ES8302021A1 (en) | 3-0-Demethyl derivatives of istamycin B series compounds and their preparation. | |
| GB1482532A (en) | Method for producing cephem derivatives | |
| ES449142A1 (en) | Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins | |
| EP0304858A3 (en) | Cephem compounds, their production and use | |
| GB1456767A (en) | Preparation of 7alpha-methoxy-cephalosporins and 6alpha-methoxy- penicillins | |
| GB1398564A (en) | 1-amino substituted-1-cycloalkane derivatives of 6-amino penicillanic acid | |
| GB1339010A (en) | Tetrazolyl-anthraquinone derivatives | |
| GB1452692A (en) | Amino substituted acylthio cephalosporins | |
| GB1420728A (en) | Cephalosporins | |
| ES8307819A1 (en) | Cephalosporin derivatives, pharmaceutical compositions containing the same and production thereof. | |
| GB1410852A (en) | Substituted 4-biphenylyl-butenoic acids esters and amides and pharmaceutical compositions containing them | |
| GB8519264D0 (en) | Chemical compounds | |
| ATE48138T1 (en) | CEPHALOSPORIN COMPOUNDS. | |
| GB1435847A (en) | Esters of alpha-alkylidene-aminobenzyl penicillins |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |