GB1413449A - Carbanilides and process for the preparation thereof - Google Patents
Carbanilides and process for the preparation thereofInfo
- Publication number
- GB1413449A GB1413449A GB2289374A GB2289374A GB1413449A GB 1413449 A GB1413449 A GB 1413449A GB 2289374 A GB2289374 A GB 2289374A GB 2289374 A GB2289374 A GB 2289374A GB 1413449 A GB1413449 A GB 1413449A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- group
- urea group
- carbanilides
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 abstract 3
- 239000000344 soap Substances 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N urea group Chemical group NC(=O)N XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
- XFKLCOFARDPKCT-UHFFFAOYSA-N 3,4-dibromo-2-hydroxy-n-phenylbenzamide Chemical compound OC1=C(Br)C(Br)=CC=C1C(=O)NC1=CC=CC=C1 XFKLCOFARDPKCT-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 239000003899 bactericide agent Substances 0.000 abstract 1
- 235000013877 carbamide Nutrition 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 abstract 1
- 229960004068 hexachlorophene Drugs 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- KVSKGMLNBAPGKH-UHFFFAOYSA-N tribromosalicylanilide Chemical compound OC1=C(Br)C=C(Br)C=C1C(=O)NC1=CC=C(Br)C=C1 KVSKGMLNBAPGKH-UHFFFAOYSA-N 0.000 abstract 1
- ICUTUKXCWQYESQ-UHFFFAOYSA-N triclocarban Chemical compound C1=CC(Cl)=CC=C1NC(=O)NC1=CC=C(Cl)C(Cl)=C1 ICUTUKXCWQYESQ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
Abstract
1413449 Antimicrobial application of substituted ureas L GIVAUDAN & CIE SA 22 May 1974 [23 May 1973] 22893/74 Heading A5E [Also in Divisions C2 and C5] Antibacterial compositions such as soaps and cosmetic compositions comprise a compound of formula I wherein R<SP>1</SP> and R<SP>2</SP>, which may be the same or different and which are attached in positions o- or mrelative to the urea group, are hydrogen or chlorine and R<SP>3</SP>, which is in an m or p position relative to the urea group, is a group of formula in which m is 1, 2 or 3, y is 2 to 7 and x+y is 2m + 1 together with known soap constituents, optionally other bacteriocides e.g. 3, 4, 4'-trichlorocarbanilide, hexachlorophene dibromosalicylanilide, tribromosalicylanilide or a mixture of the latter two.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US363206A US3860645A (en) | 1973-05-23 | 1973-05-23 | Bacteriostatic substituted carbanilides |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1413449A true GB1413449A (en) | 1975-11-12 |
Family
ID=23429270
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2289374A Expired GB1413449A (en) | 1973-05-23 | 1974-05-22 | Carbanilides and process for the preparation thereof |
Country Status (13)
Country | Link |
---|---|
US (1) | US3860645A (en) |
JP (1) | JPS5047941A (en) |
AT (1) | AT336631B (en) |
AU (1) | AU476065B2 (en) |
BE (1) | BE815418A (en) |
CA (1) | CA1026769A (en) |
CH (1) | CH586194A5 (en) |
DE (1) | DE2422243A1 (en) |
FR (1) | FR2230627B1 (en) |
GB (1) | GB1413449A (en) |
IL (1) | IL44410A (en) |
NL (1) | NL7405417A (en) |
ZA (1) | ZA741631B (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2928485A1 (en) * | 1979-07-14 | 1981-01-29 | Bayer Ag | USE OF UREA DERIVATIVES AS A MEDICINAL PRODUCT IN THE TREATMENT OF FATTY METABOLISM DISORDERS |
JPH0395153A (en) * | 1989-06-15 | 1991-04-19 | Mitsubishi Kasei Corp | Diphenyl urea derivative |
US6344476B1 (en) * | 1997-05-23 | 2002-02-05 | Bayer Corporation | Inhibition of p38 kinase activity by aryl ureas |
US7329670B1 (en) * | 1997-12-22 | 2008-02-12 | Bayer Pharmaceuticals Corporation | Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas |
US7517880B2 (en) | 1997-12-22 | 2009-04-14 | Bayer Pharmaceuticals Corporation | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas |
US20080300281A1 (en) * | 1997-12-22 | 2008-12-04 | Jacques Dumas | Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas |
US20080269265A1 (en) * | 1998-12-22 | 2008-10-30 | Scott Miller | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas |
US8124630B2 (en) * | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
US7351834B1 (en) | 1999-01-13 | 2008-04-01 | Bayer Pharmaceuticals Corporation | ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
US7928239B2 (en) | 1999-01-13 | 2011-04-19 | Bayer Healthcare Llc | Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas |
EP2298311B1 (en) * | 1999-01-13 | 2012-05-09 | Bayer HealthCare LLC | w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors |
WO2000042012A1 (en) | 1999-01-13 | 2000-07-20 | Bayer Corporation | φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS |
US7235576B1 (en) | 2001-01-12 | 2007-06-26 | Bayer Pharmaceuticals Corporation | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
US7371763B2 (en) * | 2001-04-20 | 2008-05-13 | Bayer Pharmaceuticals Corporation | Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas |
SI1450799T1 (en) * | 2001-12-03 | 2007-02-28 | Bayer Pharmaceuticals Corp | Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers |
US20080108672A1 (en) * | 2002-01-11 | 2008-05-08 | Bernd Riedl | Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors |
AU2003210969A1 (en) * | 2002-02-11 | 2003-09-04 | Bayer Corporation | Aryl ureas with raf kinase and angiogenesis inhibiting activity |
US20030216396A1 (en) * | 2002-02-11 | 2003-11-20 | Bayer Corporation | Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors |
WO2003068746A1 (en) * | 2002-02-11 | 2003-08-21 | Bayer Pharmaceuticals Corporation | Aryl ureas as kinase inhibitors |
MXPA04007832A (en) * | 2002-02-11 | 2005-09-08 | Bayer Pharmaceuticals Corp | Aryl ureas with angiogenesis inhibiting activity. |
US7557129B2 (en) | 2003-02-28 | 2009-07-07 | Bayer Healthcare Llc | Cyanopyridine derivatives useful in the treatment of cancer and other disorders |
CA2526617C (en) * | 2003-05-20 | 2015-04-28 | Bayer Pharmaceuticals Corporation | Diaryl ureas with kinase inhibiting activity |
UA84156C2 (en) * | 2003-07-23 | 2008-09-25 | Байер Фармасьютикалс Корпорейшн | Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2818930A (en) * | 1948-08-07 | 1958-01-07 | Joseph B Kucera | Three-wheeled vehicle having a high arched front frame |
US2745874A (en) * | 1953-06-18 | 1956-05-15 | Geigy Ag J R | Insecticidal derivatives of diphenyl urea |
US2846398A (en) * | 1955-12-27 | 1958-08-05 | Monsanto Chemicals | Antiseptic detergent composition |
-
1973
- 1973-05-23 US US363206A patent/US3860645A/en not_active Expired - Lifetime
-
1974
- 1974-03-12 ZA ZA00741631A patent/ZA741631B/en unknown
- 1974-03-12 IL IL44410A patent/IL44410A/en unknown
- 1974-03-14 AU AU66650/74A patent/AU476065B2/en not_active Expired
- 1974-03-21 CH CH393074A patent/CH586194A5/xx not_active IP Right Cessation
- 1974-04-22 NL NL7405417A patent/NL7405417A/xx unknown
- 1974-05-08 DE DE2422243A patent/DE2422243A1/en active Pending
- 1974-05-13 JP JP49053157A patent/JPS5047941A/ja active Pending
- 1974-05-21 FR FR7417631A patent/FR2230627B1/fr not_active Expired
- 1974-05-22 BE BE144645A patent/BE815418A/en unknown
- 1974-05-22 AT AT426874A patent/AT336631B/en not_active IP Right Cessation
- 1974-05-22 GB GB2289374A patent/GB1413449A/en not_active Expired
- 1974-05-22 CA CA200,572A patent/CA1026769A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2230627B1 (en) | 1977-09-30 |
IL44410A (en) | 1977-10-31 |
JPS5047941A (en) | 1975-04-28 |
FR2230627A1 (en) | 1974-12-20 |
AU6665074A (en) | 1975-09-18 |
AU476065B2 (en) | 1976-09-09 |
CH586194A5 (en) | 1977-03-31 |
BE815418A (en) | 1974-11-22 |
US3860645A (en) | 1975-01-14 |
NL7405417A (en) | 1974-11-26 |
ATA426874A (en) | 1976-09-15 |
ZA741631B (en) | 1975-01-29 |
CA1026769A (en) | 1978-02-21 |
AT336631B (en) | 1977-05-10 |
DE2422243A1 (en) | 1974-12-12 |
IL44410A0 (en) | 1974-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |