GB1408198A - Antiviral compositions - Google Patents

Antiviral compositions

Info

Publication number
GB1408198A
GB1408198A GB3933572A GB3933572A GB1408198A GB 1408198 A GB1408198 A GB 1408198A GB 3933572 A GB3933572 A GB 3933572A GB 3933572 A GB3933572 A GB 3933572A GB 1408198 A GB1408198 A GB 1408198A
Authority
GB
United Kingdom
Prior art keywords
phenylthioureido
groups
aug
cycloalkyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3933572A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medizinska Akademia
Original Assignee
Medizinska Akademia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medizinska Akademia filed Critical Medizinska Akademia
Publication of GB1408198A publication Critical patent/GB1408198A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1408198 Antiviral compostions containing thiourea derivatives MEDIZINSKA AKADEMIA 23 Aug 1972 [23 Aug 1971] 39335/72 Heading A5B A pharmaceutical composition comprises a thiourea derivative having activity against picornaviruses and having the general formula wherein R is H or a methyl group and R<SP>1</SP> is an alkyl, cycloalkyl or alkenyl group, or an aralkyl or aryl hydrocarbon group, an alkyl, cycloalkyl or alkenyl group substituted by one or more amino, hydroxy, carboxyl or phenylthioureido groups, an aryl or aralkyl hydrocarbon group substituted by one or more substituents which may be the same or different and are selected from amino, acylamino, nitro, halo, hydroxy, carboxy, acyl, alkoxy and phenylthioureido groups, or a pyridyl, aminopyridyl, quinolyl or furfuryl group optionally substituted by one or more phenylthioureido groups, in association with a solid non-toxic pharmaceutically acceptable carrier therefor or in the form of a sterile injectable solution or suspension.
GB3933572A 1971-08-23 1972-08-23 Antiviral compositions Expired GB1408198A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG1729471 1971-08-23

Publications (1)

Publication Number Publication Date
GB1408198A true GB1408198A (en) 1975-10-01

Family

ID=3897739

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3933572A Expired GB1408198A (en) 1971-08-23 1972-08-23 Antiviral compositions

Country Status (4)

Country Link
JP (1) JPS4828609A (en)
DE (1) DE2241470A1 (en)
FR (1) FR2150834B1 (en)
GB (1) GB1408198A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005007601A3 (en) * 2003-07-10 2005-06-23 Achillion Pharmaceuticals Inc Substituted arylthiourea derivatives useful as inhibitors of viral replication
WO2005067900A2 (en) * 2004-01-06 2005-07-28 Achillion Pharmaceuticals, Inc. Azabenzofuran substituted thioureas as inhibitors of viral replication

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780483A (en) * 1995-02-17 1998-07-14 Smithkline Beecham Corporation IL-8 receptor antagonists
WO1996025157A1 (en) 1995-02-17 1996-08-22 Smithkline Beecham Corporation Il-8 receptor antagonists
US6005008A (en) * 1996-02-16 1999-12-21 Smithkline Beecham Corporation IL-8 receptor antagonists
US6211373B1 (en) 1996-03-20 2001-04-03 Smithkline Beecham Corporation Phenyl urea antagonists of the IL-8 receptor
US6262113B1 (en) 1996-03-20 2001-07-17 Smithkline Beecham Corporation IL-8 receptor antagonists
AU3499497A (en) 1996-06-27 1998-01-14 Smithkline Beecham Corporation Il-8 receptor antagonists
TR199802694T2 (en) * 1996-06-27 1999-03-22 Smithkline Beecham Corporation IL-8 resept�r kar��tlar�

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005007601A3 (en) * 2003-07-10 2005-06-23 Achillion Pharmaceuticals Inc Substituted arylthiourea derivatives useful as inhibitors of viral replication
EA010017B1 (en) * 2003-07-10 2008-06-30 Ачиллион Фармасьютикалз, Инк. Substituted arylthiourea derivatives useful as inhibitors of viral replication
US7718671B2 (en) 2003-07-10 2010-05-18 Achillion Pharmaceuticals, Inc. Substituted arylthiourea derivatives useful as inhibitors of viral replication
WO2005067900A2 (en) * 2004-01-06 2005-07-28 Achillion Pharmaceuticals, Inc. Azabenzofuran substituted thioureas as inhibitors of viral replication
WO2005067900A3 (en) * 2004-01-06 2005-09-29 Achillion Pharmaceuticals Inc Azabenzofuran substituted thioureas as inhibitors of viral replication
US7439374B2 (en) 2004-01-06 2008-10-21 Achillion Pharmaceuticals, Inc. Azabenzofuran substituted thioureas; inhibitors of viral replication

Also Published As

Publication number Publication date
DE2241470A1 (en) 1973-03-22
FR2150834B1 (en) 1975-10-17
FR2150834A1 (en) 1973-04-13
JPS4828609A (en) 1973-04-16

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee