GB1401518A - Anti-acne compositions - Google Patents
Anti-acne compositionsInfo
- Publication number
- GB1401518A GB1401518A GB5838472A GB5838472A GB1401518A GB 1401518 A GB1401518 A GB 1401518A GB 5838472 A GB5838472 A GB 5838472A GB 5838472 A GB5838472 A GB 5838472A GB 1401518 A GB1401518 A GB 1401518A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- group
- bis
- biguamide
- heptyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
- C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Abstract
1401518 Anti-acne preparations MERCK & CO INC 18 Dec 1972 [23 Dec 1971] 58384/72 Heading A5B An anti-acne gel, emulsion or unflavoured lotion comprises (a) an inert pharmaceutical diluent and (b) a compound of formula or a salt thereof wherein R is C 6-16 alkyl, alkoxyalkyl or alkylthioalkyl, R<SP>1</SP> is H or lower alkyl, x is 1 or 2 and A is one of (i) C 2-12 alkylene in which the two valencies connecting to the remainder of the molecule are not on the same carbon atom, (ii) a group of formula wherein m and n are 2-6 and Y is 0 or S (iii) a group of formula (iv) a group of formula wherein Z and Z' are C 1-3 alkylene or (v) a group of formula wherein Q is O, S, SO, SO 2 or a group of formula Compounds specified include 1, 1'-hexamethylene-bis[5-(n-hexyl)-biguamide], the corresponding n-heptyl, n-octyl, 2-ethylhexyl, nonyl, 3- hexyl, 3-octyl, and decyl compounds, 1, I'-hexamethylene-bis[5-(1, 1, 3, 3-tetramethylbutyl)- biguamide], and 1, 1'-(2-methyl-1, 4-butylene) bis[5-(heptyl)-biguanide].
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21169871A | 1971-12-23 | 1971-12-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1401518A true GB1401518A (en) | 1975-07-16 |
Family
ID=22787989
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5838472A Expired GB1401518A (en) | 1971-12-23 | 1972-12-18 | Anti-acne compositions |
Country Status (8)
Country | Link |
---|---|
AU (1) | AU463632B2 (en) |
BE (1) | BE793229A (en) |
CA (1) | CA991081A (en) |
DE (1) | DE2263130A1 (en) |
FR (1) | FR2164802B1 (en) |
GB (1) | GB1401518A (en) |
NL (1) | NL7216738A (en) |
ZA (1) | ZA729031B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7105573B2 (en) * | 2000-02-23 | 2006-09-12 | Orentreich Foundation For The Advancement Of Science, Inc. | Methods and compositions for the treatment of alopecia and other disorders of the pilosebaceous apparatus |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1525120A (en) * | 1974-12-19 | 1978-09-20 | Nelson Res & Dev | Topical antimicrobial compositions |
GB1538903A (en) * | 1975-04-11 | 1979-01-24 | Nelson Res & Dev | Carrier for a topically applied physiologically active agent or cosmetic agent |
CA1090253A (en) * | 1976-11-01 | 1980-11-25 | Edward D. Thompson | Anti-acne composition |
US4163800A (en) * | 1977-08-17 | 1979-08-07 | The Procter & Gamble Company | Topical composition and treatment of skin lesions therewith |
US4478821A (en) * | 1982-01-26 | 1984-10-23 | The Gillette Company | Inhibition of body odor |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR6568736D0 (en) * | 1964-04-09 | 1973-08-14 | Drug Inc Sterling | PROCESS TO PREPARE A BISGUANIDE |
US3468898A (en) * | 1966-05-26 | 1969-09-23 | Sterling Drug Inc | Bridged bis-biguanides and bis-guanidines |
-
0
- BE BE793229D patent/BE793229A/en not_active IP Right Cessation
-
1972
- 1972-12-08 NL NL7216738A patent/NL7216738A/xx not_active Application Discontinuation
- 1972-12-12 AU AU49962/72A patent/AU463632B2/en not_active Expired
- 1972-12-15 CA CA159,142A patent/CA991081A/en not_active Expired
- 1972-12-18 GB GB5838472A patent/GB1401518A/en not_active Expired
- 1972-12-21 ZA ZA729031A patent/ZA729031B/en unknown
- 1972-12-21 FR FR7245672A patent/FR2164802B1/fr not_active Expired
- 1972-12-22 DE DE2263130A patent/DE2263130A1/en not_active Ceased
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7105573B2 (en) * | 2000-02-23 | 2006-09-12 | Orentreich Foundation For The Advancement Of Science, Inc. | Methods and compositions for the treatment of alopecia and other disorders of the pilosebaceous apparatus |
Also Published As
Publication number | Publication date |
---|---|
NL7216738A (en) | 1973-06-26 |
ZA729031B (en) | 1974-08-28 |
DE2263130A1 (en) | 1973-06-28 |
AU4996272A (en) | 1974-06-13 |
CA991081A (en) | 1976-06-15 |
BE793229A (en) | 1973-06-22 |
FR2164802A1 (en) | 1973-08-03 |
AU463632B2 (en) | 1975-07-31 |
FR2164802B1 (en) | 1975-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |