GB1382965A - Morpholine derivatives - Google Patents
Morpholine derivativesInfo
- Publication number
- GB1382965A GB1382965A GB3391273A GB3391273A GB1382965A GB 1382965 A GB1382965 A GB 1382965A GB 3391273 A GB3391273 A GB 3391273A GB 3391273 A GB3391273 A GB 3391273A GB 1382965 A GB1382965 A GB 1382965A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- hydrogen
- carbon atoms
- morpholine derivatives
- morpholine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1382965 Morpholine derivatives IMPERIAL CHEMICAL INDUSTRIES Ltd 18 July 1973 [11 Aug 1972] 33912/73 Divided out of 1382526 Heading C2C [Also in Division A5] The invention comprises novel therapeutic compounds (I) (including salts thereof) wherein R<SP>1</SP> is hydrogen or an acyl radical of up to 4 carbon atoms; R<SP>2</SP> is hydrogen or an alkyl radical of 1 to 6 carbon atoms; R<SP>3</SP> is a halogen atom, an alkyl radical of 1 to 4 carbon atoms, a methoxy radical, a methylthio radical or a trifluoromethyl radical; and R<SP>4</SP> is hydrogen or a trifluormethyl radical. They are made by standard methods, e.g. by hydrolysis or by using compounds corresponding to (I) where the N-atom of the morpholine ring is benzylated.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3391273A GB1382965A (en) | 1972-08-11 | 1972-08-11 | Morpholine derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3391273A GB1382965A (en) | 1972-08-11 | 1972-08-11 | Morpholine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1382965A true GB1382965A (en) | 1975-02-05 |
Family
ID=10359027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3391273A Expired GB1382965A (en) | 1972-08-11 | 1972-08-11 | Morpholine derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1382965A (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993015052A1 (en) * | 1992-01-28 | 1993-08-05 | Smithkline Beecham Plc | Compounds as calcium channel antagonists |
WO2000071518A2 (en) * | 1999-05-25 | 2000-11-30 | Sepracor, Inc. | Heterocyclic analgesic compounds and their use |
WO2001092226A1 (en) * | 2000-05-25 | 2001-12-06 | Sepracor, Inc. | Heterocyclic analgesic compounds and method of use thereof |
US6635661B2 (en) | 2000-05-25 | 2003-10-21 | Sepracor Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US6677332B1 (en) | 1999-05-25 | 2004-01-13 | Sepracor, Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US7132551B2 (en) | 2000-09-11 | 2006-11-07 | Sepracor Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof |
US7294637B2 (en) | 2000-09-11 | 2007-11-13 | Sepracor, Inc. | Method of treating addiction or dependence using a ligand for a monamine receptor or transporter |
US7361666B2 (en) | 1999-05-25 | 2008-04-22 | Sepracor, Inc. | Heterocyclic analgesic compounds and methods of use thereof |
-
1972
- 1972-08-11 GB GB3391273A patent/GB1382965A/en not_active Expired
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993015052A1 (en) * | 1992-01-28 | 1993-08-05 | Smithkline Beecham Plc | Compounds as calcium channel antagonists |
AU777760B2 (en) * | 1999-05-25 | 2004-10-28 | Sepracor, Inc. | Heterocyclic analgesic compounds and methods of use thereof |
WO2000071518A2 (en) * | 1999-05-25 | 2000-11-30 | Sepracor, Inc. | Heterocyclic analgesic compounds and their use |
WO2000071518A3 (en) * | 1999-05-25 | 2001-10-18 | Sepracor Inc | Heterocyclic analgesic compounds and their use |
US7361666B2 (en) | 1999-05-25 | 2008-04-22 | Sepracor, Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US7129228B2 (en) | 1999-05-25 | 2006-10-31 | Sepracor Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US6677332B1 (en) | 1999-05-25 | 2004-01-13 | Sepracor, Inc. | Heterocyclic analgesic compounds and methods of use thereof |
WO2001092226A1 (en) * | 2000-05-25 | 2001-12-06 | Sepracor, Inc. | Heterocyclic analgesic compounds and method of use thereof |
US6645980B1 (en) | 2000-05-25 | 2003-11-11 | Sepracor Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US6635661B2 (en) | 2000-05-25 | 2003-10-21 | Sepracor Inc. | Heterocyclic analgesic compounds and methods of use thereof |
US7132551B2 (en) | 2000-09-11 | 2006-11-07 | Sepracor Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof |
US7294637B2 (en) | 2000-09-11 | 2007-11-13 | Sepracor, Inc. | Method of treating addiction or dependence using a ligand for a monamine receptor or transporter |
US7517892B2 (en) | 2000-09-11 | 2009-04-14 | Sepracor Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof |
US7816375B2 (en) | 2000-09-11 | 2010-10-19 | Sepracor Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |