GB1360536A - Pyridoxyl-l-aspartic acid salt - Google Patents

Pyridoxyl-l-aspartic acid salt

Info

Publication number
GB1360536A
GB1360536A GB1950072A GB1950072A GB1360536A GB 1360536 A GB1360536 A GB 1360536A GB 1950072 A GB1950072 A GB 1950072A GB 1950072 A GB1950072 A GB 1950072A GB 1360536 A GB1360536 A GB 1360536A
Authority
GB
United Kingdom
Prior art keywords
pyridoxyl
aspastate
monopotassium
acid salt
aspartic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1950072A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes de Produits Chimiques SA
Original Assignee
Societe dEtudes de Produits Chimiques SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes de Produits Chimiques SA filed Critical Societe dEtudes de Produits Chimiques SA
Priority to GB1950072A priority Critical patent/GB1360536A/en
Priority to FR7310228A priority patent/FR2181843B1/fr
Publication of GB1360536A publication Critical patent/GB1360536A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • C07D213/66One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal

Abstract

1360536 Pyridoxyl aspastate salt SOC E ETUDES DE PRODUITS CHIMIQUES 30 March 1973 [25 April 1972] 19500/72 Heading C2C Monopotassium pyridoxyl - l - aspastate of formula is prepared by reacting pyridoxal with dipotassium - l - aspastate and reducing in situ with HBH 4 the Schiffs base so formed followed by addition of mineral acid to yield the monopotassium slat. Pharmaceutical compositions in conventional forms having cardiac analeptic activity comprise the above compound and carriers or diluents.
GB1950072A 1972-04-25 1972-04-25 Pyridoxyl-l-aspartic acid salt Expired GB1360536A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB1950072A GB1360536A (en) 1972-04-25 1972-04-25 Pyridoxyl-l-aspartic acid salt
FR7310228A FR2181843B1 (en) 1972-04-25 1973-03-22

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1950072A GB1360536A (en) 1972-04-25 1972-04-25 Pyridoxyl-l-aspartic acid salt

Publications (1)

Publication Number Publication Date
GB1360536A true GB1360536A (en) 1974-07-17

Family

ID=10130402

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1950072A Expired GB1360536A (en) 1972-04-25 1972-04-25 Pyridoxyl-l-aspartic acid salt

Country Status (2)

Country Link
FR (1) FR2181843B1 (en)
GB (1) GB1360536A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288716A (en) * 1987-02-18 1994-02-22 Ulrich Speck Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
US6339085B1 (en) 1999-03-08 2002-01-15 The University Of Manitoba Therapeutics for cardiovascular and related diseases
US6417204B1 (en) 2000-07-07 2002-07-09 Medicure International Inc. Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics
US6489345B1 (en) 1999-07-13 2002-12-03 Medicure, Inc. Treatment of diabetes and related pathologies
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
US6605612B2 (en) 2000-02-29 2003-08-12 Medicure International Inc. Cardioprotective phosohonates and malonates
US6677356B1 (en) 1999-08-24 2004-01-13 Medicure International Inc. Treatment of cardiovascular and related pathologies
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US7812037B2 (en) 2004-10-28 2010-10-12 Medicure International, Inc. Dual antiplatelet/anticoagulant pyridoxine analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2542869A (en) * 1948-03-19 1951-02-20 Merck & Co Inc N-pyridoxyl-amino acids and process of preparing the same

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288716A (en) * 1987-02-18 1994-02-22 Ulrich Speck Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis
US6066659A (en) * 1987-02-18 2000-05-23 Steigerwald Arzneimittelwerk Gmbh Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
US7230009B2 (en) 1999-03-08 2007-06-12 Medicure, Inc. Pyridoxal analogues and methods of treatment
US6339085B1 (en) 1999-03-08 2002-01-15 The University Of Manitoba Therapeutics for cardiovascular and related diseases
US6890943B2 (en) 1999-03-08 2005-05-10 Medicure Inc. Pyridoxal analogues and methods of treatment
US6489345B1 (en) 1999-07-13 2002-12-03 Medicure, Inc. Treatment of diabetes and related pathologies
US6677356B1 (en) 1999-08-24 2004-01-13 Medicure International Inc. Treatment of cardiovascular and related pathologies
US7125889B2 (en) 1999-08-24 2006-10-24 Medicure International Inc. Treating of cardiovascular and related pathologies
US7144892B2 (en) 1999-08-24 2006-12-05 Merrill Lynch Capital Canada Inc. Treatment of cardiovascular and related pathologies
US7148233B2 (en) 1999-08-24 2006-12-12 Merrill Lynch Capital Canada Inc. Treatment of cardiovascular and related pathologies
US7132430B2 (en) 1999-08-24 2006-11-07 Medicure International Inc. Treatment of cardiovascular and related pathologies
US7115625B2 (en) 1999-08-24 2006-10-03 Medicure International Inc. Treatment of cardiovascular and related pathologies
US7115626B2 (en) 1999-08-24 2006-10-03 Medicure International Inc. Treatment of cardiovascular and related pathologies
US6605612B2 (en) 2000-02-29 2003-08-12 Medicure International Inc. Cardioprotective phosohonates and malonates
US6667315B2 (en) 2000-02-29 2003-12-23 Medicure International Inc. Cardioprotective phosphonates and malonates
US6780997B2 (en) 2000-02-29 2004-08-24 Medicure International Inc. Cardioprotective phosphonates and malonates
US6867215B2 (en) 2000-02-29 2005-03-15 Medicure International Inc. Cardioprotective phosphonates and malonates
US7105673B2 (en) 2000-02-29 2006-09-12 Medicure International Inc. Cardioprotective phosphonates and malonates
US6861439B2 (en) 2000-03-28 2005-03-01 Medicure International, Inc. Treatment of cerebrovascular disease
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US6417204B1 (en) 2000-07-07 2002-07-09 Medicure International Inc. Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US7812037B2 (en) 2004-10-28 2010-10-12 Medicure International, Inc. Dual antiplatelet/anticoagulant pyridoxine analogs

Also Published As

Publication number Publication date
FR2181843B1 (en) 1976-05-21
FR2181843A1 (en) 1973-12-07

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee