GB1356346A - Immunological reagents - Google Patents
Immunological reagentsInfo
- Publication number
- GB1356346A GB1356346A GB1711871A GB1711871A GB1356346A GB 1356346 A GB1356346 A GB 1356346A GB 1711871 A GB1711871 A GB 1711871A GB 1711871 A GB1711871 A GB 1711871A GB 1356346 A GB1356346 A GB 1356346A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sheep
- gamma globulin
- reagin
- labelled
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
1356346 Immunological testing PHARMACIA AB 26 May 1971 [27 May 1970] 17118/71 Heading G1B A reagent-combination for use in carrying out tests on samples of human origin utilizing an immunological reaction between an antigen (1) and an antibody (2), one of which is of ovine or bovine origin comprises either antigen (1) or antibody (2), and non-human animal gamma globulin (3) for reaction with heterophile antibodies present in the sample under test, the non-human animal gamma globulin (3) being contained separately from (1) or (2) or being mixed with (1) or (2). The antigen (1) or antibody (2) may be chemically or physically bound to carrier particles (for example co-polymers of dextran and epichlorhydrin, or to microcrystalline cellulose or cellulose in the form of a paper disc or to a tube of plastics material) and may be radio-actively labelled or labelled with colour producing atom or group, for example with fluorescein. The non-human gamma globulin (3) may be horse, sheep or bovine. Examples relate to determination of reagin-Ig directed against cow epithelium where the reagents are allergen bound to dextranepichlorhydrin co-polymer resin treated with cyanogen bromide or to microcrystalline cellulose, sheep anti-reagin epsilon fragments, I<125> labelled reagin, with bovine serum to provide component (3); determination of reagin-Ig directed against horse epithelium using allergen bound to cross-linked dextran substituted with isothiocyanotophenoxyhydroxypropyl groups and sheep anti-reagin Fc fragments labelled with I<125>, with horse or sheep gamma globulin as component (3); pregnancy tests using latex particles coated with sheep anti-HCG and bovine or sheep gamma globulin as component (3); determination of IgE using sheep-anti IgE bound to dextran-epichlorhydrin copolymer resin treated with cyanogen bromide, and IgE labelled with I<125>, with sheep gamma globulin as component (3).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE727070 | 1970-05-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1356346A true GB1356346A (en) | 1974-06-12 |
Family
ID=20270914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1711871A Expired GB1356346A (en) | 1970-05-27 | 1971-05-26 | Immunological reagents |
Country Status (6)
Country | Link |
---|---|
AU (1) | AU2919171A (en) |
CH (1) | CH538692A (en) |
DE (1) | DE2126128A1 (en) |
FR (1) | FR2093840A5 (en) |
GB (1) | GB1356346A (en) |
NL (1) | NL7107245A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4289748A (en) * | 1979-05-31 | 1981-09-15 | United States Of America | Ultrasensitive enzymatic radioimmunoassay method |
WO1990010226A1 (en) * | 1989-02-21 | 1990-09-07 | Pitman-Moore, Inc. | Preventing false-positive results in elisa-assay methods |
GB2496122A (en) * | 2011-10-31 | 2013-05-08 | Ge Healthcare Bio Sciences Ab | Biological sample preservation on paper |
US11266337B2 (en) | 2015-09-09 | 2022-03-08 | Drawbridge Health, Inc. | Systems, methods, and devices for sample collection, stabilization and preservation |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4170454A (en) * | 1978-03-30 | 1979-10-09 | Union Carbide Corporation | Process for the preparation of a solid-phase radioimmunoassay support and use thereof |
JPS60256057A (en) * | 1984-06-01 | 1985-12-17 | Dai Ichi Pure Chem Co Ltd | Immunological measurement |
DE3715333A1 (en) * | 1987-05-08 | 1988-11-24 | Behringwerke Ag | METHOD FOR THE QUANTITATIVE DETERMINATION OF SERUM PROTEINS IN BODY LIQUIDS, AND MEANS FOR IMPLEMENTING THE METHOD |
-
1971
- 1971-05-24 AU AU29191/71A patent/AU2919171A/en not_active Expired
- 1971-05-26 NL NL7107245A patent/NL7107245A/xx unknown
- 1971-05-26 GB GB1711871A patent/GB1356346A/en not_active Expired
- 1971-05-26 DE DE19712126128 patent/DE2126128A1/en active Pending
- 1971-05-26 CH CH769871A patent/CH538692A/en not_active IP Right Cessation
- 1971-05-27 FR FR7119363A patent/FR2093840A5/fr not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4289748A (en) * | 1979-05-31 | 1981-09-15 | United States Of America | Ultrasensitive enzymatic radioimmunoassay method |
WO1990010226A1 (en) * | 1989-02-21 | 1990-09-07 | Pitman-Moore, Inc. | Preventing false-positive results in elisa-assay methods |
GB2496122A (en) * | 2011-10-31 | 2013-05-08 | Ge Healthcare Bio Sciences Ab | Biological sample preservation on paper |
US10371608B2 (en) | 2011-10-31 | 2019-08-06 | Ge Healthcare Bio-Sciences Ab | Sample preservation method and sample preservation substrate |
US11266337B2 (en) | 2015-09-09 | 2022-03-08 | Drawbridge Health, Inc. | Systems, methods, and devices for sample collection, stabilization and preservation |
Also Published As
Publication number | Publication date |
---|---|
CH538692A (en) | 1973-06-30 |
AU2919171A (en) | 1972-11-30 |
FR2093840A5 (en) | 1972-01-28 |
DE2126128A1 (en) | 1971-12-09 |
NL7107245A (en) | 1971-11-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |