GB1330160A - Particle analyzer - Google Patents
Particle analyzerInfo
- Publication number
- GB1330160A GB1330160A GB6208170A GB6208170A GB1330160A GB 1330160 A GB1330160 A GB 1330160A GB 6208170 A GB6208170 A GB 6208170A GB 6208170 A GB6208170 A GB 6208170A GB 1330160 A GB1330160 A GB 1330160A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pore
- membrane
- particles
- constriction
- naoh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002245 particle Substances 0.000 title abstract 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 6
- 239000012528 membrane Substances 0.000 abstract 4
- 239000011148 porous material Substances 0.000 abstract 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 239000011521 glass Substances 0.000 abstract 2
- 229920001817 Agar Polymers 0.000 abstract 1
- 239000000020 Nitrocellulose Substances 0.000 abstract 1
- FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 abstract 1
- 239000008272 agar Substances 0.000 abstract 1
- 238000005054 agglomeration Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 239000000919 ceramic Substances 0.000 abstract 1
- 239000000084 colloidal system Substances 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 239000003792 electrolyte Substances 0.000 abstract 1
- 229920006333 epoxy cement Polymers 0.000 abstract 1
- 230000004992 fission Effects 0.000 abstract 1
- 239000006194 liquid suspension Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000010445 mica Substances 0.000 abstract 1
- 229910052618 mica group Inorganic materials 0.000 abstract 1
- 239000012229 microporous material Substances 0.000 abstract 1
- 229920001220 nitrocellulos Polymers 0.000 abstract 1
- 238000005192 partition Methods 0.000 abstract 1
- 238000000053 physical method Methods 0.000 abstract 1
- 239000004033 plastic Substances 0.000 abstract 1
- 229920000515 polycarbonate Polymers 0.000 abstract 1
- 239000004417 polycarbonate Substances 0.000 abstract 1
- 229920001225 polyester resin Polymers 0.000 abstract 1
- 239000004645 polyester resin Substances 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- 238000004513 sizing Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
- G01N15/13—Details pertaining to apertures
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
1330160 Electro-physical measurement particle analysis GENERAL ELECTRIC CO 31 Dec 1970 [20 Feb 1970] 62081/70 Heading G1N In apparatus for analyzing particles especially colloids in a liquid suspension they are ELECTROPHORETICALLY DRIVEN through a constriction and the resulting impedance changes and time-of passage through the constriction is used to determine the number, size and mobility of the particles. The application may be to sizing and counting blood cells. As described a container is provided with a removable partition of ceramic, plastic or glass, having an aperture covered by a membrane having a pore therein of e.g. 1..50 microns diameter. MEMBRANE CONSTRUCTION preferably a sheet of polycarbonate less than 20 microns thick is subjected to particle radiation to cause fission tracking and then etched e.g. in NaOH. A small segment having the required sized hole is chosen and using a steromicroscope any other pores are coated with epoxy cement and layers stripped off the membrane to produce the required thickness. The preferred pore-size-ratio is an L/D of 5:1 Alternative materials are glass, mica polyester resins, or cellulostic, or a pair of membranes may be used separated by a microporous material (agar, cellulose nitrate etc) to reduce electroosmatic effects, Fig.4 (not shown). The particles are added to the electrolyte which may be NaCl; KCl, HCl, NaOH, with a surfactant to reduce agglomeration and clogging of the pore. This may be unlocked by ultrasonic agitation. The signals may be monitored by a C.R.T, peak voltmeter, or counter.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1311570A | 1970-02-20 | 1970-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1330160A true GB1330160A (en) | 1973-09-12 |
Family
ID=21758383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6208170A Expired GB1330160A (en) | 1970-02-20 | 1970-12-31 | Particle analyzer |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5038358B1 (en) |
| DE (1) | DE2107214A1 (en) |
| FR (1) | FR2078439A5 (en) |
| GB (1) | GB1330160A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105728069A (en) * | 2016-01-30 | 2016-07-06 | 深圳市贝沃德克生物技术研究院有限公司 | Multi-channel micro-fluidic chip for rapid blood self-inspection |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60192926A (en) * | 1984-03-14 | 1985-10-01 | Yokogawa Hokushin Electric Corp | Optical fiber network |
-
1970
- 1970-12-17 JP JP45112528A patent/JPS5038358B1/ja active Pending
- 1970-12-31 GB GB6208170A patent/GB1330160A/en not_active Expired
-
1971
- 1971-02-10 FR FR7104471A patent/FR2078439A5/fr not_active Expired
- 1971-02-16 DE DE19712107214 patent/DE2107214A1/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105728069A (en) * | 2016-01-30 | 2016-07-06 | 深圳市贝沃德克生物技术研究院有限公司 | Multi-channel micro-fluidic chip for rapid blood self-inspection |
| CN105728069B (en) * | 2016-01-30 | 2021-01-19 | 深圳市安测健康信息技术有限公司 | Multi-channel micro-fluidic chip for rapidly self-checking blood |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5038358B1 (en) | 1975-12-09 |
| FR2078439A5 (en) | 1971-11-05 |
| DE2107214A1 (en) | 1971-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |