GB1321368A - Organo-phosphorus compounds useful for the control of helminths in warm-blooded animals - Google Patents
Organo-phosphorus compounds useful for the control of helminths in warm-blooded animalsInfo
- Publication number
- GB1321368A GB1321368A GB3199271A GB3199271A GB1321368A GB 1321368 A GB1321368 A GB 1321368A GB 3199271 A GB3199271 A GB 3199271A GB 3199271 A GB3199271 A GB 3199271A GB 1321368 A GB1321368 A GB 1321368A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- alkyl
- compound
- helminths
- warm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241001465754 Metazoa Species 0.000 title abstract 4
- 244000000013 helminth Species 0.000 title abstract 2
- 150000002903 organophosphorus compounds Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 229940124339 anthelmintic agent Drugs 0.000 abstract 1
- 239000000921 anthelmintic agent Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000006277 halobenzyl group Chemical group 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- -1 oxydimethylene Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/44—Amides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2479—Compounds containing the structure P(=X)n-N-acyl, P(=X)n-N-heteroatom, P(=X)n-N-CN (X = O, S, Se; n = 0, 1)
- C07F9/2487—Compounds containing the structure P(=X)n-N-acyl, P(=X)n-N-heteroatom, P(=X)n-N-CN (X = O, S, Se; n = 0, 1) containing the structure P(=X)n-N-C(=X) (X = O, S, Se; n = 0, 1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/36—Amides thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1321368 Anthelmintics AMERICAN CYANAMID CO 7 July 1971 [27 July 1970 (2) 15 April 1971 (2)] 31992/71 Heading A5B [Also in Division C2] A pharmaceutical composition useful for the control of helminths in warm-blooded animals comprises as active ingredient a compound of formula I: where R and R 1 are C 1-4 alkyl or alkoxy, or phenyl, Y is -NH-CS-S- or -N=C (SR 3 )-S- where R 3 is C 1-4 alkyl or alkenyl, benzyl or halobenzyl, and R 2 is C 1-4 alkylene, C 1-4 alkyl-substituted C 1-4 alkylene, or oxydimethylene, together with a pharmaceutically acceptable carrier, with the proviso that except for those compounds of formula I which are novel (see Division C2), compositions consisting only of a compound of formula I and water or a pharmaceutically acceptable common organic solvent are excluded. The active ingredient is preferably present in the composition as a single oral dose of 1.25 to 30 mg per kg of animal body weight. The composition may be an animal feed composition comprising a nutritionally balanced feed and 0.001 to 1.0% by weight of a compound of formula I.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5867670A | 1970-07-27 | 1970-07-27 | |
| US5867770A | 1970-07-27 | 1970-07-27 | |
| US13445471A | 1971-04-15 | 1971-04-15 | |
| US13445371A | 1971-04-15 | 1971-04-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1321368A true GB1321368A (en) | 1973-06-27 |
Family
ID=27490006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3199271A Expired GB1321368A (en) | 1970-07-27 | 1971-07-07 | Organo-phosphorus compounds useful for the control of helminths in warm-blooded animals |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE770496A (en) |
| DE (1) | DE2137593A1 (en) |
| FR (1) | FR2100956B1 (en) |
| GB (1) | GB1321368A (en) |
| IL (1) | IL37126A (en) |
| NL (1) | NL7109104A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2975480A (en) * | 1958-03-19 | 1961-03-21 | Yanush Konstant | Apparatus for making felt boots |
| EP3235815A1 (en) | 2016-04-19 | 2017-10-25 | Philipps-Universität Marburg | Agents against parasitic helminths |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1580929A (en) * | 1967-05-24 | 1969-09-12 |
-
1971
- 1971-06-23 IL IL37126A patent/IL37126A/en unknown
- 1971-07-01 NL NL7109104A patent/NL7109104A/xx unknown
- 1971-07-07 GB GB3199271A patent/GB1321368A/en not_active Expired
- 1971-07-26 BE BE770496A patent/BE770496A/en unknown
- 1971-07-27 FR FR7127505A patent/FR2100956B1/fr not_active Expired
- 1971-07-27 DE DE19712137593 patent/DE2137593A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NL7109104A (en) | 1972-01-31 |
| IL37126A0 (en) | 1971-08-25 |
| BE770496A (en) | 1972-01-26 |
| DE2137593A1 (en) | 1972-02-03 |
| FR2100956A1 (en) | 1972-03-24 |
| IL37126A (en) | 1974-09-10 |
| FR2100956B1 (en) | 1974-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |