GB1320104A - Hepta-and octapeptides - Google Patents
Hepta-and octapeptidesInfo
- Publication number
- GB1320104A GB1320104A GB1320104DA GB1320104A GB 1320104 A GB1320104 A GB 1320104A GB 1320104D A GB1320104D A GB 1320104DA GB 1320104 A GB1320104 A GB 1320104A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hepta
- prepared
- peptides
- alanine
- carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1320104 Hepta- and octa-peptides NORWICH PHARMACAL CO 20 May 1971 16116/71 Heading C2C [Also in Division C3] Compounds (I) (which counteract hypertension due to angiotensin amide) (where R is H, succinyl, L-aspartyl, sarcosyl, L-seryl, succinamyl, L-protyl, glycyl, D- or L- asparaginyl; R 1 is an L-alanine, L- or D-leucine, glycine, L-isoleucine or beta-alanine residue and R 2 is L-valyl, L-isoleucyl or L-alanyl) are prepared in known manner for synthesizing peptides, especially by the Merrifield method using a chloromethylated styrene-divinyl copolymer as carrier. His(N<SP>im</SP>Bzl)-Pro-Ala OH 2HBr is prepared as an intermediate after removal of the polymer carrier.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1611671 | 1971-05-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1320104A true GB1320104A (en) | 1973-06-13 |
Family
ID=10071472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1320104D Expired GB1320104A (en) | 1971-05-20 | 1971-05-20 | Hepta-and octapeptides |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1320104A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2398050A1 (en) * | 1977-07-18 | 1979-02-16 | Richter Gedeon Vegyeszet | NEW ANTAGONIST ANALOGUES OF ANGIOTENSIN II CONTAINING A-AMINE OXACID AT POSITION 1 |
FR2398049A1 (en) * | 1977-07-18 | 1979-02-16 | Richter Gedeon Vegyeszet | NEW ANALOGUES OF ANGIOTENSIN II AND PROCESS FOR PREPARING THEM |
FR2407199A1 (en) * | 1977-10-25 | 1979-05-25 | Searle & Co | NEW DERIVATIVES OF SARCOSIN1 DEHYDROALANINE8 ANGIOTENSIN II, USEFUL IN PARTICULAR AS ANGIOTENSIN INHIBITORS, AND THEIR PREPARATION METHODS |
-
1971
- 1971-05-20 GB GB1320104D patent/GB1320104A/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2398050A1 (en) * | 1977-07-18 | 1979-02-16 | Richter Gedeon Vegyeszet | NEW ANTAGONIST ANALOGUES OF ANGIOTENSIN II CONTAINING A-AMINE OXACID AT POSITION 1 |
FR2398049A1 (en) * | 1977-07-18 | 1979-02-16 | Richter Gedeon Vegyeszet | NEW ANALOGUES OF ANGIOTENSIN II AND PROCESS FOR PREPARING THEM |
FR2407199A1 (en) * | 1977-10-25 | 1979-05-25 | Searle & Co | NEW DERIVATIVES OF SARCOSIN1 DEHYDROALANINE8 ANGIOTENSIN II, USEFUL IN PARTICULAR AS ANGIOTENSIN INHIBITORS, AND THEIR PREPARATION METHODS |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
PE20 | Patent expired after termination of 20 years |