GB1312205A - Method and composition for lowering blood pressure - Google Patents
Method and composition for lowering blood pressureInfo
- Publication number
- GB1312205A GB1312205A GB1832071A GB1832071A GB1312205A GB 1312205 A GB1312205 A GB 1312205A GB 1832071 A GB1832071 A GB 1832071A GB 1832071 A GB1832071 A GB 1832071A GB 1312205 A GB1312205 A GB 1312205A
- Authority
- GB
- United Kingdom
- Prior art keywords
- composition
- alkyl
- blood pressure
- lowering blood
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1312205 Hypertensive compositions MARION LABORATORIES Inc 1 June 1971 [9 Sept 1970] 18320/71 Heading A5B Pharmaceutical compositions, in unit dosage form and suitable for oral or parenteral administration, comprise 0.02 to 300 mg of tetrahydroisoquinoline derivatives of the formula: wherein R is a phenyl group substituted by 1 to 3 halogen atoms, or OH, NO 2 , alkyl or alkoxy groups and R 1 is H or alkyl, or non- toxic acid addition salts thereof in admixture with pharmaceutical carriers. The compounds possess hypotensive activity.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7090070A | 1970-09-09 | 1970-09-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1312205A true GB1312205A (en) | 1973-04-04 |
Family
ID=22098044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1832071A Expired GB1312205A (en) | 1970-09-09 | 1971-06-01 | Method and composition for lowering blood pressure |
Country Status (6)
Country | Link |
---|---|
JP (1) | JPS4824396B1 (en) |
BE (1) | BE763149R (en) |
CH (1) | CH550797A (en) |
DE (1) | DE2101691A1 (en) |
FR (1) | FR2106399B2 (en) |
GB (1) | GB1312205A (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50123994U (en) * | 1974-03-26 | 1975-10-09 | ||
US20010016657A1 (en) * | 1997-03-18 | 2001-08-23 | Smithkline Beecham P.L.C. | Substituted isoquinoline derivatives and their use as anticonvulsants |
WO1999021836A1 (en) * | 1997-10-24 | 1999-05-06 | Smithkline Beecham Plc | Substituted isoquinoline derivatives and their use as anticonvulsants |
JP2005526723A (en) * | 2002-02-15 | 2005-09-08 | グラクソ グループ リミテッド | Vanilloid receptor modulator |
SI2046787T1 (en) | 2006-08-01 | 2011-07-29 | Glaxo Group Ltd | PYRAZOLO?á3,4-B?åPYRIDINE COMPOUNDS, AND THEIR USE AS PDE4 INHIBITORS |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3674791A (en) * | 1968-03-26 | 1972-07-04 | Marion Laboratories Inc | Benzamido 2 lower alkyl decahydroisoquinolines |
-
1970
- 1970-12-28 JP JP11953270A patent/JPS4824396B1/ja active Pending
-
1971
- 1971-01-15 DE DE19712101691 patent/DE2101691A1/en active Pending
- 1971-02-18 BE BE763149A patent/BE763149R/en active
- 1971-05-17 CH CH732371A patent/CH550797A/en not_active IP Right Cessation
- 1971-06-01 GB GB1832071A patent/GB1312205A/en not_active Expired
- 1971-09-08 FR FR7132410A patent/FR2106399B2/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CH550797A (en) | 1974-06-28 |
FR2106399A2 (en) | 1972-05-05 |
BE763149R (en) | 1971-07-16 |
FR2106399B2 (en) | 1974-10-18 |
JPS4824396B1 (en) | 1973-07-20 |
DE2101691A1 (en) | 1972-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |