GB1297476A - - Google Patents

Info

Publication number
GB1297476A
GB1297476A GB1297476DA GB1297476A GB 1297476 A GB1297476 A GB 1297476A GB 1297476D A GB1297476D A GB 1297476DA GB 1297476 A GB1297476 A GB 1297476A
Authority
GB
United Kingdom
Prior art keywords
acetate
active
propionate
water
glycol ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1297476A publication Critical patent/GB1297476A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

1297476 Microgranulate FARBENFABRIKEN BAYER AG 19 April 1971 [4 March 1970] 22308/71 Heading A5B [Also in Division B8] Solid, free-flowing, substantially spherical particles (microgranulates) are prepared by dispersing or dissolving an "active" material in a solution of a cellulose ester in a glycol ether and introducing discrete droplets of the resultant into water whereby the glycol ether is given up to the water and the droplets become solidified and may be separated. Suitable cellulose esters are: cellulose acetate, propionate, propionate acetate and butyrate acetate preferably having 2.2 to 2.6 acyl radicals per anhydroglucose unit. Suitable glycol ethers are mono- and di-alkyl ethers of aliphatic glycols having 1 to 6 carbon atoms in the alkyl group. Examples relate to processes in which the "active" material is: aspirin, paraffin oil, TiO 2 and the compound (CH 3 O) 2 PO (CHOH-CCl 3 ).
GB1297476D 1970-03-04 1971-04-19 Expired GB1297476A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702010116 DE2010116A1 (en) 1970-03-04 1970-03-04 Process for the production of micro-granules

Publications (1)

Publication Number Publication Date
GB1297476A true GB1297476A (en) 1972-11-22

Family

ID=5764038

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1297476D Expired GB1297476A (en) 1970-03-04 1971-04-19

Country Status (13)

Country Link
JP (1) JPS5344424B1 (en)
AT (1) AT310127B (en)
BE (1) BE763791A (en)
CA (1) CA922588A (en)
CH (1) CH549408A (en)
CS (1) CS158290B2 (en)
DE (1) DE2010116A1 (en)
ES (1) ES388917A1 (en)
FR (1) FR2084200A5 (en)
GB (1) GB1297476A (en)
IL (1) IL36222A (en)
TR (1) TR16847A (en)
ZA (1) ZA711052B (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4609542A (en) * 1978-12-22 1986-09-02 Elan Corporation, P.L.C. New pharmaceutical forms for administration of medicaments by oral route, with programmed release
WO1999055774A1 (en) * 1998-04-24 1999-11-04 Eastman Chemical Company Coprecipitation of cellulose esters with functional additives and compositions thus obtainable
EP1044683A1 (en) * 1999-04-15 2000-10-18 Debio Recherche Pharmaceutique S.A. One-step dispersion method for the microencapsulation of water soluble substances
EP1151741A1 (en) * 2000-05-05 2001-11-07 L'oreal Microcapsules with an aqueous core containing at least an active water-soluble cosmetic or dermatologic ingredient and cosmetic or dermatologic compositions containing these microcapsules
WO2005061095A1 (en) * 2003-12-24 2005-07-07 Mg Pharmacy Inc. Process for producing microsphere and apparatus for producing the same
US9156016B2 (en) 2010-09-30 2015-10-13 Midatech Pharma (Wales) Limited Apparatus and method for making solid beads
US9259701B2 (en) 2010-09-30 2016-02-16 Q Chip Ltd. Method for making solid beads
WO2019238892A1 (en) * 2018-06-15 2019-12-19 Taminco Bvba Treatment of poultry or pigs for reducing the feed conversion ratio or increasing their bodyweight gain

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
DD160393A3 (en) * 1980-11-14 1983-07-27 Horst Dautzenberg MICRO CAPSULES AND METHOD FOR THE PRODUCTION THEREOF
JP2534691B2 (en) * 1986-12-26 1996-09-18 トツパン・ム−ア株式会社 Method for producing high-density microcapsules

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4609542A (en) * 1978-12-22 1986-09-02 Elan Corporation, P.L.C. New pharmaceutical forms for administration of medicaments by oral route, with programmed release
WO1999055774A1 (en) * 1998-04-24 1999-11-04 Eastman Chemical Company Coprecipitation of cellulose esters with functional additives and compositions thus obtainable
US6777002B1 (en) 1999-04-15 2004-08-17 Debio Recherche Pharmaceutique S.A. Process for microencapsulation of water soluble substances
WO2000062761A1 (en) * 1999-04-15 2000-10-26 Debio Recherche Pharmaceutique S.A. Process for microencapsulation of water soluble substances
EP1044683A1 (en) * 1999-04-15 2000-10-18 Debio Recherche Pharmaceutique S.A. One-step dispersion method for the microencapsulation of water soluble substances
EP1151741A1 (en) * 2000-05-05 2001-11-07 L'oreal Microcapsules with an aqueous core containing at least an active water-soluble cosmetic or dermatologic ingredient and cosmetic or dermatologic compositions containing these microcapsules
US6531160B2 (en) 2000-05-05 2003-03-11 L′Oreal Microcapsules with an aqueous core containing at least one water-soluble cosmetic or dermatological active principle and cosmetic or dermatological compositions containing them
WO2005061095A1 (en) * 2003-12-24 2005-07-07 Mg Pharmacy Inc. Process for producing microsphere and apparatus for producing the same
US9156016B2 (en) 2010-09-30 2015-10-13 Midatech Pharma (Wales) Limited Apparatus and method for making solid beads
US9259701B2 (en) 2010-09-30 2016-02-16 Q Chip Ltd. Method for making solid beads
WO2019238892A1 (en) * 2018-06-15 2019-12-19 Taminco Bvba Treatment of poultry or pigs for reducing the feed conversion ratio or increasing their bodyweight gain
CN112334011A (en) * 2018-06-15 2021-02-05 塔明克公司 Treatment of poultry or pigs for reducing feed conversion ratio or increasing weight gain
CN112334011B (en) * 2018-06-15 2024-03-29 塔明克私人有限公司 Treatment of poultry or pigs to reduce feed conversion or increase weight gain

Also Published As

Publication number Publication date
CS158290B2 (en) 1974-10-15
CH549408A (en) 1974-05-31
SU379074A3 (en) 1973-04-18
JPS5344424B1 (en) 1978-11-29
IL36222A (en) 1973-08-29
TR16847A (en) 1973-07-01
DE2010116A1 (en) 1971-09-16
ES388917A1 (en) 1974-02-16
ZA711052B (en) 1971-10-27
CA922588A (en) 1973-03-13
AT310127B (en) 1973-09-25
BE763791A (en) 1971-08-02
IL36222A0 (en) 1971-04-28
FR2084200A5 (en) 1971-12-17

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees