GB1290593A - - Google Patents

Info

Publication number
GB1290593A
GB1290593A GB1290593DA GB1290593A GB 1290593 A GB1290593 A GB 1290593A GB 1290593D A GB1290593D A GB 1290593DA GB 1290593 A GB1290593 A GB 1290593A
Authority
GB
United Kingdom
Prior art keywords
hydrocarbon radical
april
optionally substituted
alk
cardiac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH519069A external-priority patent/CH529721A/en
Application filed filed Critical
Publication of GB1290593A publication Critical patent/GB1290593A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1290593 Cardiac and circulatory medicines CIBA GEIGY AG 3 April 1970 [3 April 1969 9 April 1969 17 Feb 1970] 15918/70 Heading A5B [Also in Division C2] Pharmaceutical compositions comprise a compound of the formula: R-alk-OPhOCH 2 CH(OH)CH 2 NHR 1 (alk=alkylene; R=unsaturated aliphatic hydrocarbon radical; R 1 =C 1-15 aliphatic hydrocarbon radical optionally interrupted by O, S, NH and/or substituted by one or more OH groups, optionally substituted C 3-15 cycloaliphatic hydrocarbon radical or optionally substituted araliphatic-hydrocarbon radical containing up to 15 carbon atoms; Ph=optionally substituted pphenylene) or condensation product thereof with an aldehyde or ketone, or salt thereof, with or without other active ingredients (e.g. cardiac or circulatory drugs and/or psychotropic agents), in association with a carrier. The primary active ingredients are #-blockers and anti-hypertensives.
GB1290593D 1969-04-03 1970-04-03 Expired GB1290593A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH519069A CH529721A (en) 1969-04-03 1969-04-03 Unsatd. amine(s), tranquillisers and vasodilators
CH545069 1969-04-09
CH228070 1970-02-17

Publications (1)

Publication Number Publication Date
GB1290593A true GB1290593A (en) 1972-09-27

Family

ID=27173592

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1290593D Expired GB1290593A (en) 1969-04-03 1970-04-03

Country Status (7)

Country Link
AU (1) AU1320070A (en)
DE (1) DE2014346A1 (en)
ES (1) ES378163A1 (en)
FR (1) FR2038200A1 (en)
GB (1) GB1290593A (en)
NL (1) NL7004728A (en)
OA (1) OA03248A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3205457A1 (en) * 1982-02-16 1983-08-25 Merck Patent Gmbh, 6100 Darmstadt OXAZOLIDIN-2-ONE

Also Published As

Publication number Publication date
FR2038200A1 (en) 1971-01-08
ES378163A1 (en) 1973-08-01
AU1320070A (en) 1971-10-07
NL7004728A (en) 1970-10-06
DE2014346A1 (en) 1970-10-08
OA03248A (en) 1970-12-15

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees