GB1269852A - 6-trifluoromethyl-tryptophane and process for producing the same - Google Patents

6-trifluoromethyl-tryptophane and process for producing the same

Info

Publication number
GB1269852A
GB1269852A GB9658/71A GB965871A GB1269852A GB 1269852 A GB1269852 A GB 1269852A GB 9658/71 A GB9658/71 A GB 9658/71A GB 965871 A GB965871 A GB 965871A GB 1269852 A GB1269852 A GB 1269852A
Authority
GB
United Kingdom
Prior art keywords
trifluoromethyl
tryptophane
producing
same
april
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB9658/71A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Priority claimed from GB07639/69A external-priority patent/GB1269851A/en
Publication of GB1269852A publication Critical patent/GB1269852A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/205—Heterocyclic compounds
    • A23L27/2054—Heterocyclic compounds having nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Indole Compounds (AREA)

Abstract

1,269,852. 6-Trifluoromethyl-tryptophane. ELI LILLY & CO. 3 April, 1969 [8 April, 1968 (2)], No. 9658/71. Divided out of 1,269,851. Heading C2C. 6 - Trifluoromethyl - tryptophane is prepared by reaction of 6-trifluoromethyl-indole with formaldehyde and diethylamine to give 3-diethylaminoethyl - 6 - trifluoromethyl indole and reacting this with diethyl formamidomalonate to give diethyl (6-trifluoromethyl-3-indolylmethyl)- formamidomalonate, followed by hydrolysis and decarboxylation. The product is a sweetening agent.
GB9658/71A 1968-04-08 1969-04-03 6-trifluoromethyl-tryptophane and process for producing the same Expired GB1269852A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71966668A 1968-04-08 1968-04-08
US71973068A 1968-04-08 1968-04-08
GB07639/69A GB1269851A (en) 1968-04-08 1969-04-03 Sweetened compositions

Publications (1)

Publication Number Publication Date
GB1269852A true GB1269852A (en) 1972-04-06

Family

ID=27257528

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9658/71A Expired GB1269852A (en) 1968-04-08 1969-04-03 6-trifluoromethyl-tryptophane and process for producing the same

Country Status (1)

Country Link
GB (1) GB1269852A (en)

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