GB1246315A - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
GB1246315A
GB1246315A GB49497/68A GB4949768A GB1246315A GB 1246315 A GB1246315 A GB 1246315A GB 49497/68 A GB49497/68 A GB 49497/68A GB 4949768 A GB4949768 A GB 4949768A GB 1246315 A GB1246315 A GB 1246315A
Authority
GB
United Kingdom
Prior art keywords
preparation
component
cytostatic
plasmakinin
oct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB49497/68A
Inventor
Egon Stuermer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1246315A publication Critical patent/GB1246315A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/043Kallidins; Bradykinins; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

1,246,315. Cytostatic preparations. SANDOZ Ltd. 18 Oct., 1968 [20 Oct., 1967; 28 Feb., 1968], No. 49497/68. Heading A5B. Cytostatic preparations for the treatment of malignant tumours comprise a cytostatic component comprising a hydrazide derivative of podophyllinic acid (especially the ethyl hydrazide) and a plasmakinin component comprising kallidin, methionyl hallidin or bradykinin. The preparation may comprise from 400 to 1600 mg. of the hydrazide derivative of podophyllinic acid and from 5 to 200γ of the plasmakinin component. The preparation may be administered intra-arterially e.g. by infusion of aqueous solutions containing NaCl or glucose. The preparation may be in the form of a pack comprising the two components, preferably contained in separate ampoules so that the components may either be separately administered simultaneously or may first be admixed and administered.
GB49497/68A 1967-10-20 1968-10-18 Pharmaceutical compositions Expired GB1246315A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1472767 1967-10-20
CH289468 1968-02-28

Publications (1)

Publication Number Publication Date
GB1246315A true GB1246315A (en) 1971-09-15

Family

ID=25691663

Family Applications (1)

Application Number Title Priority Date Filing Date
GB49497/68A Expired GB1246315A (en) 1967-10-20 1968-10-18 Pharmaceutical compositions

Country Status (5)

Country Link
BE (1) BE722587A (en)
DE (1) DE1803492A1 (en)
FR (1) FR7979M (en)
GB (1) GB1246315A (en)
SE (1) SE352533B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4152425A (en) * 1976-12-17 1979-05-01 Thera Gesellschaft Fur Patentverwertung Mbh Glucose containing infusion solution

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268164A (en) * 1990-04-23 1993-12-07 Alkermes, Inc. Increasing blood-brain barrier permeability with permeabilizer peptides
US5112596A (en) * 1990-04-23 1992-05-12 Alkermes, Inc. Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4152425A (en) * 1976-12-17 1979-05-01 Thera Gesellschaft Fur Patentverwertung Mbh Glucose containing infusion solution

Also Published As

Publication number Publication date
BE722587A (en) 1969-04-18
DE1803492A1 (en) 1969-06-26
SE352533B (en) 1973-01-08
FR7979M (en) 1970-06-08

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