GB1238894A - - Google Patents
Info
- Publication number
- GB1238894A GB1238894A GB1238894DA GB1238894A GB 1238894 A GB1238894 A GB 1238894A GB 1238894D A GB1238894D A GB 1238894DA GB 1238894 A GB1238894 A GB 1238894A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oct
- prepared
- acid esters
- esterification
- alkanoic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1,238,894. #-Guanidino alkanoic acid esters. S. FUJII. 23 Oct., 1968 [24 Oct., 1967 (2)], No. 50414/68. Heading C2C. #-Guanidino alkanoic acid esters of general formula H 2 NC(:NH)NH(CH 2 ) n COOR (in which R is a carboxylbenzyl group which may carry further groups and n is 3, 4 or 5) and their acid addition salts, may be prepared (a) by esterification of the corresponding free carboxylic acids with an alcohol ROH, or (b) by reacting a carboxybenzyl #-amino alkanoate (prepared by conventional esterification) with either S-methylthiourea or cyanamide. The compounds inhibit the hydrolysis of arginine ester by kallikrein and of casein by plasmin, and may be administered in conventional enteral or parenteral forms.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP42068693A JPS502494B1 (en) | 1967-10-24 | 1967-10-24 | |
JP6869267 | 1967-10-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1238894A true GB1238894A (en) | 1971-07-14 |
Family
ID=26409892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1238894D Expired GB1238894A (en) | 1967-10-24 | 1968-10-23 |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE1804999C3 (en) |
GB (1) | GB1238894A (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1167678B (en) * | 1960-12-09 | 1964-04-09 | Motobecane Ateliers | Power transmission for mopeds |
BE757496A (en) * | 1969-10-14 | 1971-03-16 | Ono Pharmaceutical Co | NEW PHENYL ESTERS OF GUANIDINOCAPROIC ACID AND THEIR PRODUCTION |
AT397247B (en) * | 1992-05-26 | 1994-02-25 | Chemie Linz Gmbh | GUANIDINOHYDROXYACETIC ACID, METHOD FOR THE PRODUCTION AND USE |
TW300883B (en) * | 1994-07-26 | 1997-03-21 | Kao Corp |
-
1968
- 1968-10-23 GB GB1238894D patent/GB1238894A/en not_active Expired
- 1968-10-24 DE DE19681804999 patent/DE1804999C3/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE1804999C3 (en) | 1980-11-06 |
DE1804999A1 (en) | 1969-05-22 |
DE1804999B2 (en) | 1976-09-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |