GB1212459A - Naphthacene derivatives - Google Patents

Naphthacene derivatives

Info

Publication number
GB1212459A
GB1212459A GB49280/68A GB4928068A GB1212459A GB 1212459 A GB1212459 A GB 1212459A GB 49280/68 A GB49280/68 A GB 49280/68A GB 4928068 A GB4928068 A GB 4928068A GB 1212459 A GB1212459 A GB 1212459A
Authority
GB
United Kingdom
Prior art keywords
formula
group
naphthacene
oct
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB49280/68A
Inventor
Georges Jolles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Publication of GB1212459A publication Critical patent/GB1212459A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,212,459. Naphthacene derivatives. RHONEPOULENC S.A. 17 Oct., 1968 [18 Oct., 1967], No. 49280/68. Heading C2A. Novel naphthacene derivatives of the general formula wherein R 1 and R 2 are the same or different and each represents an oxygen atom or a group of the formula =N-NR 3 R 4 , and R 3 represents H or an alkyl, alkanoyl, thioalkanoyl, aryl, aroyl, carbamoyl, thiocarbamoyl, or amidino group, these groups being optionally substituted and R 4 represents H, or R 3 and R 4 together with the nitrogen atom to which they are attached represent a piperazin-1-yl group which carries on the second nitrogen atom an optionally substituted alkyl group, and salts thereof, are prepared by reacting a compound of the formula or an acid addition salt thereof with a compound of formula Pharmaceutical compositions comprise as active ingredient a naphthacene derivative of the first general formula above, or a non-toxic salt thereof and a pharmaceutically acceptable carrier or coating.
GB49280/68A 1967-10-18 1968-10-17 Naphthacene derivatives Expired GB1212459A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR124943 1967-10-18

Publications (1)

Publication Number Publication Date
GB1212459A true GB1212459A (en) 1970-11-18

Family

ID=8640288

Family Applications (1)

Application Number Title Priority Date Filing Date
GB49280/68A Expired GB1212459A (en) 1967-10-18 1968-10-17 Naphthacene derivatives

Country Status (16)

Country Link
AT (1) AT282823B (en)
BE (1) BE722460A (en)
BR (1) BR6803181D0 (en)
CH (1) CH492697A (en)
DE (1) DE1803892A1 (en)
DK (1) DK128113B (en)
ES (1) ES359293A1 (en)
FI (1) FI49984C (en)
FR (2) FR1578722A (en)
GB (1) GB1212459A (en)
IE (1) IE32420B1 (en)
IL (1) IL30899A (en)
NL (1) NL147151B (en)
NO (1) NO123574B (en)
SE (1) SE340449B (en)
YU (1) YU33665B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1920198A1 (en) * 1968-04-24 1969-11-27 Farmaceutici Italia Daunomycin derivatives with anti-cancer activity

Also Published As

Publication number Publication date
BE722460A (en) 1969-04-17
YU243668A (en) 1977-06-30
DE1803892A1 (en) 1969-05-29
SE340449B (en) 1971-11-22
BR6803181D0 (en) 1973-02-22
NL6814582A (en) 1969-04-22
IL30899A (en) 1972-11-28
FR1578722A (en) 1969-08-22
FI49984B (en) 1975-07-31
NO123574B (en) 1971-12-13
IE32420L (en) 1969-04-18
FR7123M (en) 1969-07-21
IL30899A0 (en) 1968-12-26
IE32420B1 (en) 1973-07-25
ES359293A1 (en) 1970-06-01
NL147151B (en) 1975-09-15
CH492697A (en) 1970-06-30
FI49984C (en) 1975-11-10
AT282823B (en) 1970-07-10
YU33665B (en) 1977-12-31
DK128113B (en) 1974-03-04

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee