GB1178982A - Anthelmintic Compositions - Google Patents

Anthelmintic Compositions

Info

Publication number
GB1178982A
GB1178982A GB08881/66A GB1888166A GB1178982A GB 1178982 A GB1178982 A GB 1178982A GB 08881/66 A GB08881/66 A GB 08881/66A GB 1888166 A GB1888166 A GB 1888166A GB 1178982 A GB1178982 A GB 1178982A
Authority
GB
United Kingdom
Prior art keywords
anthelmintic compositions
thienyl
phenyl
alkyl
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08881/66A
Inventor
John Burnett Davidson
Ian Hutchinson Sutherland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Priority to GB08881/66A priority Critical patent/GB1178982A/en
Publication of GB1178982A publication Critical patent/GB1178982A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,178,982. Anthelmintic compositions. MERCK & CO. Inc. 21 June, 1967 [29 April, 1966], No. 18881/66. Heading A5B. Anthelmintic compositions comprise piperazine carbodithioic acid (the complex resulting from the reaction of equimolar amounts of piperazine and CS 2 ), and a benzimidazole of the general formula: wherein R is a mono- or bi-cyclic carbocyclic aryl radical, e.g. phenyl or naphthyl, an orthohaloaryl radical, a heteroaromatic radical containing 1 to 3 heteroatoms which are N, S or O, (e.g. furyl, thienyl, pyrryl, pyridyl, coumarinyl, thiacoumarinyl, thiazolyl, isothiazolyl and thiadiazolyl), R 5 and R 6 are H, C 1-5 alkyl, C 1-5 alkoxy, C 1-5 alkylthio, phenoxy, phenylthio, halo, phenyl, halophenyl or thienyl, only one of R 5 and R 6 being other than H, and R 2 is H, C 1-5 alkyl, C 1-5 alkanoyl or benzoyl. They may be in conventional solid and liquid forms for oral administration to animals, including enteric preparations and mixed with animal feeds.
GB08881/66A 1966-04-29 1966-04-29 Anthelmintic Compositions Expired GB1178982A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB08881/66A GB1178982A (en) 1966-04-29 1966-04-29 Anthelmintic Compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08881/66A GB1178982A (en) 1966-04-29 1966-04-29 Anthelmintic Compositions

Publications (1)

Publication Number Publication Date
GB1178982A true GB1178982A (en) 1970-01-28

Family

ID=10120035

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08881/66A Expired GB1178982A (en) 1966-04-29 1966-04-29 Anthelmintic Compositions

Country Status (1)

Country Link
GB (1) GB1178982A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055171A1 (en) * 1998-04-24 1999-11-04 Künzle Farma Ag Licking stone
EP1303309A1 (en) * 2000-05-23 2003-04-23 Commonwealth Scientific And Industrial Research Organisation Rapidly-disintegrating tablets for animals

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055171A1 (en) * 1998-04-24 1999-11-04 Künzle Farma Ag Licking stone
EP1303309A1 (en) * 2000-05-23 2003-04-23 Commonwealth Scientific And Industrial Research Organisation Rapidly-disintegrating tablets for animals
EP1303309A4 (en) * 2000-05-23 2004-01-28 Commw Scient Ind Res Org Rapidly-disintegrating tablets for animals

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