GB1170798A - 00,11-Dihydro-5H-Dibenzo[a,d]Cycloheptene Derivatives - Google Patents

00,11-Dihydro-5H-Dibenzo[a,d]Cycloheptene Derivatives

Info

Publication number
GB1170798A
GB1170798A GB20979/67A GB2097967A GB1170798A GB 1170798 A GB1170798 A GB 1170798A GB 20979/67 A GB20979/67 A GB 20979/67A GB 2097967 A GB2097967 A GB 2097967A GB 1170798 A GB1170798 A GB 1170798A
Authority
GB
United Kingdom
Prior art keywords
alkyl
formula
dibenzo
dihydro
subjected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20979/67A
Inventor
Jeff Hamish Russel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wander AG
Original Assignee
Wander AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wander AG filed Critical Wander AG
Publication of GB1170798A publication Critical patent/GB1170798A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/38Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1,170,798. 5 - Aminomethyl - 10,11 - dihydro - 5H - dibenzo - [a,d] - cycloheptene derivatives. DR. A. WANDER S.A. 5 May, 1967 [10 May, 1966], No. 20979/67. Heading C2C. Novel compounds of general formula wherein R 1 is H or C 1-3 alkyl, R 2 is a C 1-3 alkyl, alkenyl or alkynyl group, R 3 is C 1-3 alkyl and one of R 4 and R 5 is H and the other is H, halogen or C 1-3 alkyl, and acid addition salts thereof are prepared by one of the following methods (a) a reactive ester of an alcohol of formula is reacted with an amine of formula H.N.R 2 R 3 ; (b) a compound of formula wherein R<SP>1</SP> is H or a C 1-3 alkyl alkenyl or alkynyl group is subjected to alkylation, alkenylation or alkynylation; or (c) a quaternary salt of formula wherein X is an acid radical is subjected to reductive cleavage, all of which may be followed by salt formation. Pharmaceutical compositions in conventional forms for enteral or parenteral administration and having anticonvulsant activity comprise an above novel compound and a carrier therefor. Reference has been directed by the Comptroller to Specification 1,115,327.
GB20979/67A 1966-05-10 1967-05-05 00,11-Dihydro-5H-Dibenzo[a,d]Cycloheptene Derivatives Expired GB1170798A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH678166A CH473759A (en) 1966-05-10 1966-05-10 Process for the preparation of 10,11-dihydro-5H-dibenzo (a, d) -cycloheptene derivatives

Publications (1)

Publication Number Publication Date
GB1170798A true GB1170798A (en) 1969-11-19

Family

ID=4314928

Family Applications (1)

Application Number Title Priority Date Filing Date
GB20979/67A Expired GB1170798A (en) 1966-05-10 1967-05-05 00,11-Dihydro-5H-Dibenzo[a,d]Cycloheptene Derivatives

Country Status (12)

Country Link
AT (3) AT283303B (en)
BE (1) BE698198A (en)
CH (3) CH481055A (en)
CS (4) CS154228B2 (en)
DE (1) DE1643212A1 (en)
ES (1) ES340257A1 (en)
FI (1) FI47348C (en)
FR (1) FR6502M (en)
GB (1) GB1170798A (en)
GR (1) GR36291B (en)
NL (1) NL6706480A (en)
NO (1) NO122246B (en)

Also Published As

Publication number Publication date
BE698198A (en) 1967-11-09
GR36291B (en) 1969-01-20
NO122246B (en) 1971-06-07
DE1643212A1 (en) 1971-03-11
AT283311B (en) 1970-08-10
FR6502M (en) 1968-12-02
CS154230B2 (en) 1974-03-29
AT283312B (en) 1970-08-10
CS154228B2 (en) 1974-03-29
CH473759A (en) 1969-06-15
AT283303B (en) 1970-08-10
FI47348B (en) 1973-07-31
CH481055A (en) 1969-11-15
CS154229B2 (en) 1974-03-29
FI47348C (en) 1973-11-12
NL6706480A (en) 1967-11-13
ES340257A1 (en) 1968-09-01
CS154231B2 (en) 1974-03-29
CH481869A (en) 1969-11-30

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