GB1142575A - 1-[m-hydroxyphenyl]-2-[1-methyl-3-phenylpropyl-(1)-amino]-ethanol-(1) p-amino benzoate and methods for its preparation - Google Patents
1-[m-hydroxyphenyl]-2-[1-methyl-3-phenylpropyl-(1)-amino]-ethanol-(1) p-amino benzoate and methods for its preparationInfo
- Publication number
- GB1142575A GB1142575A GB3725/67A GB372567A GB1142575A GB 1142575 A GB1142575 A GB 1142575A GB 3725/67 A GB3725/67 A GB 3725/67A GB 372567 A GB372567 A GB 372567A GB 1142575 A GB1142575 A GB 1142575A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- salt
- phenylpropyl
- hydroxyphenyl
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,142,575. Basic alcohol and salt. TROPON G.m.b.H., [trading as TROPONWERKE DINKLAGE & CO.]. 25 Jan., 1967 [28 Jan., 1966], No. 3725/67. Heading C2C. 1 - [m - Hydroxyphenyl] - 2 - [1 - methyl - 3 - phenylpropyl - (1) - amino]ethanol - (1) p - aminobenzoate is prepared by synthesising the base by standard methods and converting it to the salt; the salt may be reconverted to the base. Fractional crystallization of the salt yields a higher melting and a lower melting form. The base and salt increase the flow rate in the coronary sinus with only a slight increase in the flow rate in the peripheral vascular region; they may be administered in the form of pharmaceutical preparations.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DET0030347 | 1966-01-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1142575A true GB1142575A (en) | 1969-02-12 |
Family
ID=7555523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3725/67A Expired GB1142575A (en) | 1966-01-28 | 1967-01-25 | 1-[m-hydroxyphenyl]-2-[1-methyl-3-phenylpropyl-(1)-amino]-ethanol-(1) p-amino benzoate and methods for its preparation |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE693120A (en) |
| DE (1) | DE1543918A1 (en) |
| DK (1) | DK113502B (en) |
| ES (1) | ES336093A1 (en) |
| FR (1) | FR6255M (en) |
| GB (1) | GB1142575A (en) |
| NL (1) | NL6701248A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK269079A (en) * | 1978-07-03 | 1980-02-01 | Lilly Co Eli | PROCEDURE FOR THE PREPARATION OF PHENETHANOLAMINES |
| DE3473439D1 (en) * | 1983-01-31 | 1988-09-22 | Lilly Co Eli | Improvements in or relating to phenethanolamines |
-
1966
- 1966-01-28 DE DE19661543918 patent/DE1543918A1/en active Pending
-
1967
- 1967-01-19 DK DK32767A patent/DK113502B/en unknown
- 1967-01-24 BE BE693120D patent/BE693120A/xx unknown
- 1967-01-25 GB GB3725/67A patent/GB1142575A/en not_active Expired
- 1967-01-25 FR FR92516A patent/FR6255M/fr not_active Expired
- 1967-01-26 ES ES0336093A patent/ES336093A1/en not_active Expired
- 1967-01-26 NL NL6701248A patent/NL6701248A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK113502B (en) | 1969-03-31 |
| DE1543918A1 (en) | 1970-01-08 |
| FR6255M (en) | 1968-08-19 |
| BE693120A (en) | 1967-07-24 |
| NL6701248A (en) | 1967-07-31 |
| ES336093A1 (en) | 1967-12-16 |
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